Life Science Microfluidics

LSMF

The resource supports development of microfluidic, lab-on-a-chip, organs-on-chip and perfusion cell culture systems. By enabling access to expertise in microfluidic system design and microfabrication facilities, this platform supports researchers with custom development and characterization of microfluidic devices. Our engineers are highly experienced in microfluidics and bio-/neuro-microtechnology as well as precision micromilling and high resolution 3D printing of microfluidic system components. They are there to support your microfluidic system development. A network of modelling experts for physics, mechanics and fluidics is also available to provide expertise for life science applications.

The following equipment/resources are available for device manufacturing:

-Clean room facility for basic silicon and glass microfabrication as well as metal film deposition and patterning.
-SU-8 photolithography.
-High resolution direct laser exposure. Glass silicon anodic bonding.
-PDMS microfabrication.
-Precision CNC micromilling - Daltron neo series 2
-3D-printing
-- Fused Filament Fabrication
-- Stereolithography (SLA) printing) - Formlabs Form 2
-- High resolution (2um spot size, 5 um layer thickness, Build: 50*50*50 mm) Projection Micro Stereolithography - BMF microArch S230
- Fully equipped lab for microfluidic chip characterization:
-- particle imaging velocimetry
-- micro particle tracking
-- 3D microflow mapping - GDPT - General Defocusing Particle Tracking
-- Spinning disc fluorescence confocal microscopy
-- Laser vibrometry
-- Speed of sound measurement in fluids

LSMF provides engineering support in research specific development of microfluidic solutions. Support includes device design and manufacturing as well as advice in device assembly and interconnecting to commercial system components (Pumps, valves, flow control etc.) for full system functionality and training before hand-over.

Thomas Laurell (LTH) and Anja Meisner (Faculty of Medicine) are heading LSMF. The infrastructure is operated by a steering committee (6 members: Thomas Laurell, Johan Nilsson, Lars Wallman, Martin Bengtsson, Axel Tojo, Thierry Baasch) that convenes every month to follow up on new and on-going projects, instrument status, outreach. Lars Wallman oversees the running projects and provides input for our economist.  Martin Bengtsson and Axel Tojo are responsible the device design and manufacturing and service and maintenance of the instrumentation. The infrastructure also has a project assessment board, with representatives from the M, N, T faculties that screen incoming proposals.