Human immunodeficiency virus (HIV) is a major threat against health in many countries. Despite progress in treatments and more affordable drugs there is still a vast need for new findings which could further explain the mechanisms of HIV disease progression. Therefore, my research group explores the HIV genetic diversity, transmission dynamics and drug resistance. We combine a strong global health component (including projects in sub-Saharan Africa) with laboratory investigations and state-of-art computational approaches. With a similar approach we also investigate the hepatitis C virus (HCV).