Experimentell onkologi

Forskningsoutput

Forskningsoutput per år 2013 2018 2019 2020 2021 2022 2023

• 32 Artikel i vetenskaplig tidskrift
• 8 Doktorsavhandling (sammanläggning)
• 4 Översiktsartikel
• 2 Preprint (i preprint-arkiv)
• 1 Mer
  • 1 Debate/Note/Editorial

Forskningsoutput per år

Forskningsoutput per år

Sökresultat

• 2023

  Alterations to Cerebral Perfusion, Metabolite Profiles, and Neuronal Morphology in the Hippocampus and Cortex of Male and Female Mice during Chronic Exposure to a High-Salt Diet

  Meissner, A., Garcia-Serrano, A. M., Vanherle, L., Rafiee, Z., Don-Doncow, N., Skoug, C., Larsson, S., Gottschalk, M., Magnusson, M. & Duarte, J. MN., 2023, I: International Journal of Molecular Sciences. 24, 1, 300.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • diets 100%
  • hippocampus 93%
  • Metabolites 85%
  • metabolites 83%
  • Nutrition 79%

• Roadmap to the study of gene and protein phylogeny and evolution—A practical guide

  Jacques, F., Bolivar, P., Pietras, K. & Hammarlund, E. U., 2023, I: PLoS ONE. 18, 2, e0279597.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Phylogeny 100%
  • Biodiversity 76%
  • Molecular Evolution 71%
  • Computational Biology 52%
  • Databases 50%
• 2022

  Clinically relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance

  Mañas, A., Aaltonen, K., Andersson, N., Hansson, K., Adamska, A., Seger, A., Yasui, H., van den Bos, H., Radke, K., Esfandyari, J., Bhave, M. S., Karlsson, J., Spierings, D., Foijer, F., Gisselsson, D. & Bexell, D., 2022 okt. 28, I: Science Advances. 8, 43, eabq4617.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Neuroblastoma 100%
  • Heterografts 90%
  • Phenotype 34%
  • Adrenergic Agents 27%
  • Drug Therapy 25%

• DNA promoter hypermethylation of melanocyte lineage genes determines melanoma phenotype

  Sanna, A., Phung, B., Mitra, S., Lauss, M., Choi, J., Zhang, T., Njauw, C-N. J., Cordero, E., Harbst, K., Rosengren, F., Cabrita, R., Johansson, I., Isaksson, K., Ingvar, C., Carneiro, A., Brown, K., Tsao, H., Andersson, M., Pietras, K. & Jönsson, G., 2022 okt. 10, I: JCI Insight. 7, 19, e156577.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Melanocytes 100%
  • Melanoma 73%
  • Phenotype 53%
  • DNA 49%
  • Genes 35%

• Fibroblast subsets in non-small cell lung cancer: associations with survival, mutations, and immune features

  Pellinen, T., Paavolainen, L., Martín-Bernabé, A., Papatella Araujo, R., Strell, C., Mezheyeuski, A., Backman, M., La Fleur, L., Brück, O., Sjölund, J., Holmberg, E., Välimäki, K., Brunnström, H., Botling, J., Moreno-Ruiz, P., Kallioniemi, O., Micke, P. & Östman, A., 2022 sep. 9, (E-pub ahead of print) I: Journal of the National Cancer Institute.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Cancer-Associated Fibroblasts 100%
  • Non-Small Cell Lung Carcinoma 63%
  • Fibroblasts 53%
  • Mutation 40%
  • Survival 39%

• Regulatory networks and 5' partner usage of miRNA host gene fusions in breast cancer

  Hafstað, V., Søkilde, R., Häkkinen, J., Larsson, M., Vallon-Christersson, J., Rovira, C. & Persson, H., 2022, I: International Journal of Cancer. 151, 1, s. 95-106

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Gene Fusion 100%
  • MicroRNAs 74%
  • Breast Neoplasms 56%
  • Neoplasms 23%
  • Genes 19%

• Upregulated functional gene expression programmes in tumour pericytes mark progression in patients with low-grade glioma

  Oudenaarden, C., Sjölund, J. & Pietras, K., 2022, I: Molecular Oncology. 16, 2, s. 405-421

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Pericytes 100%
  • Glioma 75%
  • Glioblastoma 57%
  • Gene Expression 48%
  • Neoplasms 26%
• 2021

  Anti-tumor effects of rigosertib in high-risk neuroblastoma

  Radke, K., Hansson, K., Sjölund, J., Wolska, M., Karlsson, J., Esfandyari, J., Pietras, K., Aaltonen, K., Gisselsson, D. & Bexell, D., 2021 aug., I: Translational Oncology. 14, 8, 101149.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • ON 01910 100%
  • Neuroblastoma 50%
  • Organoids 19%
  • Neoplasms 16%
  • Vincristine 7%

• CCM3 is a gatekeeper in focal adhesions regulating mechanotransduction and YAP/TAZ signalling

  Wang, S., Englund, E., Kjellman, P., Li, Z., Ahnlide, J. K., Rodriguez-Cupello, C., Saggioro, M., Kanzaki, R., Pietras, K., Lindgren, D., Axelson, H., Prinz, C. N., Swaminathan, V. & Madsen, C. D., 2021, I: Nature Cell Biology. 23, 7, s. 758-770 13 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Cerebral Cavernous Malformations 3 100%
  • Focal Adhesions 58%
  • Cancer-Associated Fibroblasts 22%
  • Paxillin 22%
  • Focal Adhesion Protein-Tyrosine Kinases 20%

• Deciphering the temporal heterogeneity of cancer-associated fibroblast subpopulations in breast cancer

  Albjerg Venning, F., Zornhagen, K. W., Wullkopf, L., Sjölund, J., Rodriguez-Cupello, C., Kjellman, P., Morsing, M., Hajkarim, M. C., Won, K. J., Erler, J. T. & Madsen, C. D., 2021 maj 20, I: Journal of Experimental and Clinical Cancer Research. 40, 1, s. 1 21 s., 175.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Cancer-Associated Fibroblasts 100%
  • Breast Neoplasms 45%
  • fibroblast activation protein alpha 41%
  • Triple Negative Breast Neoplasms 28%
  • Neoplasms 23%

• Infection of brain pericytes underlying neuropathology of covid‐19 patients

  Bocci, M., Oudenaarden, C., Sàenz‐sardà, X., Simrén, J., Edén, A., Sjölund, J., Möller, C., Gisslén, M., Zetterberg, H., Englund, E. & Pietras, K., 2021 nov. 1, I: International Journal of Molecular Sciences. 22, 21, 11622.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Pericytes 100%
  • infectious diseases 55%
  • Neuropathology 49%
  • brain 41%
  • Marker 38%
• 2020

  Lysine-specific demethylase 1A (LSD1) restricts ex vivo propagation of human HSCs and is a target of UM171

  Subramaniam, A., Zemaitis, K., Safaee Talkhoncheh, M., Yudovich, D., Bäckström, A., Debnath, S., Chen, J., Jain, M. V., Galeev, R., Gaetani, M., Zubarev, R. A. & Larsson, J., 2020 nov. 5, I: Blood. 136, 19, s. 2151-2161 11 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Cord 100%
  • Histone 87%
  • Hematopoietic Stem Cells 80%
  • Lysine 79%
  • Histone Demethylases 23%

• Recruited fibroblasts reconstitute the peri-islet membrane: a longitudinal imaging study of human islet grafting and revascularisation

  Nilsson, J., Fardoos, R., Hansen, L., Lövkvist, H., Pietras, K., Holmberg, D. & Schmidt-Christensen, A., 2020, I: Diabetologia. 63, 1, s. 137-148

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Lycopersicon esculentum 100%
  • Longitudinal Studies 90%
  • Transplantation 83%
  • Fibroblasts 80%
  • Stromal Cells 72%

• Tertiary lymphoid structures improve immunotherapy and survival in melanoma

  Cabrita, R., Lauss, M., Sanna, A., Donia, M., Skaarup Larsen, M., Mitra, S., Johansson, I., Phung, B., Harbst, K., Vallon-Christersson, J., van Schoiack, A., Lövgren, K., Warren, S., Jirström, K., Olsson, H., Pietras, K., Ingvar, C., Isaksson, K., Schadendorf, D., Schmidt, H., & 5 andraBastholt, L., Carneiro, A., Wargo, J. A., Svane, I. M. & Jönsson, G., 2020, I: Nature. 577, 7791, s. 561-565 5 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Tertiary Lymphoid Structures 100%
  • Immunotherapy 52%
  • Melanoma 49%
  • Survival 32%
  • T-Lymphocytes 31%

• Therapeutic targeting of KSP in preclinical models of high-risk neuroblastoma

  Hansson, K., Radke, K., Aaltonen, K., Saarela, J., Mañas, A., Sjölund, J., Smith, E. M., Pietras, K., Påhlman, S., Wennerberg, K., Gisselsson, D. & Bexell, D., 2020, I: Science Translational Medicine. 12, 562, eaba4434.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Kinesin 100%
  • Neuroblastoma 77%
  • Proteins 28%
  • Heterografts 23%
  • Neoplasms 19%
• 2019

  A CD146 FACS Protocol Enriches for Luminal Keratin 14/19 Double Positive Human Breast Progenitors

  Gerdur Ísberg, Ó., Kim, J., Fridriksdottir, A. J., Morsing, M., Timmermans-Wielenga, V., Rønnov-Jessen, L., Petersen, O. W. & Villadsen, R., 2019, I: Scientific Reports. 9, 1, 14843.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Keratin-14 100%
  • Breast 50%
  • Breast Neoplasms 14%
  • Keratins 11%
  • Morphogenesis 11%

• Activin receptor-like kinase 1 is associated with immune cell infiltration and regulates CLEC14A transcription in cancer

  Bocci, M., Sjölund, J., Kurzejamska, E., Lindgren, D., Marzouka, N. A. D., Bartoschek, M., Höglund, M. & Pietras, K., 2019, I: Angiogenesis. 22, 1, s. 117-131

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Cell Marker 100%
  • Activin Receptors 91%
  • Nutrient 65%
  • Lectin 62%
  • Biological Marker 55%

• Cartilage Oligomeric Matrix Protein initiates cancer stem cells through activation of Jagged1-Notch3 signaling

  Papadakos, K. S., Bartoschek, M., Rodriguez, C., Gialeli, C., Jin, S. B., Lendahl, U., Pietras, K. & Blom, A. M., 2019, I: Matrix Biology. 81, s. 107-121

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Cartilage Oligomeric Matrix Protein 100%
  • Neoplastic Stem Cells 69%
  • Breast Neoplasms 12%
  • Ligands 9%
  • Notch Receptors 9%

• Impact of Epithelial-Stromal Interactions on Peritumoral Fibroblasts in Ductal Carcinoma in Situ

  Strell, C., Paulsson, J., Jin, S-B., Tobin, N. P., Mezheyeuski, A., Roswall, P., Mutgan, C., Mitsios, N., Johansson, H., Wickberg, S. M., Svedlund, J., Nilsson, M., Hall, P., Mulder, J., Radisky, D. C., Pietras, K., Bergh, J., Lendahl, U., Wärnberg, F. & Östman, A., 2019, I: Journal of the National Cancer Institute. 111, 9, s. 983-995

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Breast Carcinoma In Situ 100%
  • Carcinoma, Intraductal, Noninfiltrating 82%
  • Platelet-Derived Growth Factor Receptors 58%
  • Fibroblasts 51%
  • Recurrence 10%

• Noninvasive intravital high-resolution imaging of pancreatic neuroendocrine tumours

  Balan, M., Trusohamn, M., Ning, F. C., Jacob, S., Pietras, K., Eriksson, U., Berggren, P. O. & Nyqvist, D., 2019, I: Scientific Reports. 9, 1, s. 14636

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Neuroendocrine Tumors 100%
  • Neoplasms 28%
  • Anterior Chamber 15%
  • Growth 14%
  • Vascular Endothelial Growth Factor B 11%

• PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer

  Costa, T. D. F., Zhuang, T., Lorent, J., Turco, E., Olofsson, H., Masia-Balague, M., Zhao, M., Rabieifar, P., Robertson, N., Kuiper, R., Sjölund, J., Spiess, M., Hernández-Varas, P., Rabenhorst, U., Roswall, P., Ma, R., Gong, X., Hartman, J., Pietras, K., Adams, P. D., & 2 andraDefilippi, P. & Strömblad, S., 2019 aug. 9, I: Nature Communications. 10, 1, s. 1-18 3589.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • breast 100%
  • cancer 88%
  • Breast Neoplasms 60%
  • Growth 47%
  • oncogenes 28%

• Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease

  Prakash, V., Carson, B. B., Feenstra, J. M., Dass, R. A., Sekyrova, P., Hoshino, A., Petersen, J., Guo, Y., Parks, M. M., Kurylo, C. M., Batchelder, J. E., Haller, K., Hashimoto, A., Rundqivst, H., Condeelis, J. S., Allis, C. D., Drygin, D., Nieto, M. A., Andäng, M., Percipalle, P., & 8 andraBergh, J., Adameyko, I., Farrants, A. K. Ö., Hartman, J., Lyden, D., Pietras, K., Blanchard, S. C. & Vincent, C. T., 2019, I: Nature Communications. 10, 1, 2110.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • biological evolution 100%
  • ribosomes 94%
  • Plastic Property 76%
  • Estrogen 70%
  • Ribosomes 68%

• The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma

  Phung, B., Cieśla, M., Sanna, A., Guzzi, N., Beneventi, G., Cao Thi Ngoc, P., Lauss, M., Cabrita, R., Cordero, E., Bosch, A., Rosengren, F., Häkkinen, J., Griewank, K., Paschen, A., Harbst, K., Olsson, H., Ingvar, C., Carneiro, A., Tsao, H., Schadendorf, D., & 3 andraPietras, K., Bellodi, C. & Jönsson, G., 2019 juni 18, I: Cell Reports. 27, 12, s. 3573-3586.e7

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • RNA Helicases 100%
  • Melanoma 59%
  • Neoplasm Metastasis 44%
  • Microphthalmia-Associated Transcription Factor 35%
  • Protein 29%
• 2018

  Long-peptide vaccination with driver gene mutations in p53 and Kras induces cancer mutation-specific effector as well as regulatory T cell responses

  Quandt, J., Schlude, C., Bartoschek, M., Will, R., Cid-Arregui, A., Schölch, S., Reissfelder, C., Weitz, J., Schneider, M., Wiemann, S., Momburg, F. & Beckhove, P., 2018, I: OncoImmunology. 7, 12, e1500671.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Regulatory T-Lymphocytes 100%
  • Vaccination 80%
  • Peptides 64%
  • Mutation 56%
  • T-Lymphocytes 41%

• Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling

  Roswall, P., Bocci, M., Bartoschek, M., Li, H., Kristiansen, G., Jansson, S., Lehn, S., Sjölund, J., Reid, S., Larsson, C., Eriksson, P., Anderberg, C., Cortez, E., Saal, L. H., Orsmark-Pietras, C., Cordero, E., Haller, B. K., Häkkinen, J., Burvenich, I. J. G., Lim, E., & 7 andraOrimo, A., Höglund, M., Rydén, L., Moch, H., Scott, A. M., Eriksson, U. & Pietras, K., 2018 mars 12, I: Nature Medicine. 24, s. 463–473

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Platelet-Derived Growth Factor 100%
  • Hormone 86%
  • Cancer-Associated Fibroblasts 72%
  • Breast Neoplasms 55%
  • Hormones 24%

• Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing

  Bartoschek, M., Oskolkov, N., Bocci, M., Lövrot, J., Larsson, C., Sommarin, M., Madsen, C., Lindgren, D., Pekar, G., Karlsson, G., Ringnér, M., Bergh, J., Björklund, Å. K. & Pietras, K., 2018 dec. 4, I: Nature Communications. 9, 1, 5150.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • RNA Sequencing 100%
  • Cancer-Associated Fibroblasts 84%
  • sequencing 81%
  • fibroblasts 75%
  • RNA Sequence Analysis 67%
• 2017

  Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway

  Rippe, C., Zhu, B., Krawczyk, K. K., van Bavel, E., Albinsson, S., Sjölund, J., Bakker, E. N. T. P. & Swärd, K., 2017 maj 2, I: Scientific Reports. 7, 1, 1334.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Soluble Guanylyl Cyclase 100%
  • Aorta 67%
  • Hypertension 50%
  • Gene Expression 13%
  • RNA-Seq 12%
• 2016

  Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer

  Escudero-Esparza, A., Bartoschek, M., Gialeli, C., Okroj, M., Owen, S., Jirström, K., Orimo, A., Jiang, W. G., Pietras, K. & Blom, A. M., 2016, I: Oncotarget. 7, 47, s. 76920-76933 14 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Complement Inactivating Agents 100%
  • Breast Neoplasms 43%
  • Tumor Suppressor Genes 40%
  • Neoplasms 22%
  • Aldehyde Dehydrogenase 17%

• Functional malignant cell heterogeneity in pancreatic neuroendocrine tumors revealed by targeting of PDGF-DD.

  Cortez, E., Gladh, H., Braun, S., Bocci, M., Cordero, E., Björkström, N. K., Miyazaki, H., Michael, I. P., Eriksson, U., Folestad, E. & Pietras, K., 2016, I: Proceedings of the National Academy of Sciences. 113, 7, s. E864-E873

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Platelet-Derived Growth Factor 100%
  • Neuroendocrine Tumors 97%
  • Platelet-Derived Growth Factor beta Receptor 58%
  • Neoplasms 27%
  • Paracrine Communication 12%

• VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread

  Li, X., Padhan, N., Sjöström, E. O., Roche, F. P., Testini, C., Honkura, N., Sáinz-Jaspeado, M., Gordon, E., Bentley, K., Philippides, A., Tolmachev, V., Dejana, E., Stan, R. V., Vestweber, D., Ballmer-Hofer, K., Betsholtz, C., Pietras, K., Jansson, L. & Claesson-Welsh, L., 2016 mars 23, I: Nature Communications. 7, 11017.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Adherens Junctions 100%
  • Blood Pressure 97%
  • integrity 81%
  • mice 80%
  • edema 76%
• 2015

  Endothelial ALK1 Is a Therapeutic Target to Block Metastatic Dissemination of Breast Cancer.

  Cunha, S. I., Bocci, M., Lövrot, J., Eleftheriou, N., Roswall, P., Cordero, E., Lindström, L., Bartoschek, M., Haller, B. K., Pearsall, R. S., Mulivor, A. W., Kumar, R., Larsson, C., Bergh, J. & Pietras, K., 2015, I: Cancer Research. 75, 12, s. 2445-2456

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Breast Neoplasms 100%
  • Activin Receptors 47%
  • Neoplasm Metastasis 38%
  • Combination Drug Therapy 31%
  • Computational Biology 29%
• 2013

  Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination

  Anderberg, C., Cunha, S. I., Zhai, Z., Cortez, E., Pardali, E., Johnson, J. R., Franco, M., Paez-Ribes, M., Cordiner, R., Fuxe, J., Johansson, B. R., Goumans, M-J., Casanovas, O., ten Dijke, P., Arthur, H. M. & Pietras, K., 2013, I: Journal of Experimental Medicine. 210, 3, s. 563-579

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Endoglin 100%
  • Neoplasms 22%
  • Vascular Endothelial Growth Factor A 13%
  • Transforming Growth Factor beta Receptors 10%
  • Endothelial Cells 5%
  257 Nedladdningar (Pure)