Genetiska och epigenetiska studier av barnleukemi

Forskningsoutput

Forskningsoutput per år 1997 2014 2019 2020 2021 2023

• 23 Artikel i vetenskaplig tidskrift
• 5 Letter
• 1 Publicerat konferensabstract
• 1 Debate/Note/Editorial
• 1 Mer
  • 1 Översiktsartikel

Forskningsoutput per år

Forskningsoutput per år

Sökresultat

• 2023

  A cloud-based resource for genome coordinate-based exploration and large-scale analysis of chromosome aberrations and gene fusions in cancer

  Wang, J., Zheng, J., Lee, E. E., Aguilar, B., Phan, J., Abdilleh, K., Taylor, R. C., Longabaugh, W., Johansson, B., Mertens, F., Mitelman, F., Pot, D. & LaFramboise, T., 2023, (E-pub ahead of print) I: Genes Chromosomes and Cancer.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Gene Fusion 100%
  • Chromosome Aberrations 85%
  • Genome 59%
  • Neoplasms 28%
  • Datasets 23%
• 2021

  Evolution of P-wave indices during long-term follow-up as markers of atrial substrate progression in arrhythmogenic right ventricular cardiomyopathy

  Baturova, M. A., Svensson, A., Aneq, M. Å., Svendsen, J. H., Risum, N., Sherina, V., Bundgaard, H., Meurling, C., Lundin, C., Carlson, J. & Platonov, P. G., 2021, I: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 23, 1, s. i29-i37

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Arrhythmogenic Right Ventricular Dysplasia 100%
  • Lead 32%
  • Arrhythmogenic Right Ventricular Dysplasia, Familial, 5 15%
  • Advisory Committees 7%
  • Cardiac Arrhythmias 6%
• 2020

  Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls

  Walsh, R., Lahrouchi, N., Tadros, R., Kyndt, F., Glinge, C., Postema, P. G., Amin, A. S., Nannenberg, E. A., Ware, J. S., Whiffin, N., Mazzarotto, F., Škorić-Milosavljević, D., Krijger, C., Arbelo, E., Babuty, D., Barajas-Martinez, H., Beckmann, B. M., Bézieau, S., Bos, J. M., Breckpot, J., & 31 andraCampuzano, O., Castelletti, S., Celen, C., Clauss, S., Corveleyn, A., Crotti, L., Dagradi, F., de Asmundis, C., Denjoy, I., Dittmann, S., Ellinor, P. T., Ortuño, C. G., Giustetto, C., Gourraud, J. B., Hazeki, D., Horie, M., Ishikawa, T., Itoh, H., Kaneko, Y., Kanters, J. K., Kimoto, H., Kotta, M. C., Krapels, I. P. C., Kurabayashi, M., Lazarte, J., Leenhardt, A., Loeys, B. L., Lundin, C., Makiyama, T., Platonov, P. G. & Nantes Referral Center for inherited cardiac arrhythmia, 2020 sep. 7, I: Genetics in Medicine.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Brugada Syndrome 100%
  • Population Control 86%
  • Long QT Syndrome 75%
  • Cardiac Arrhythmias 61%
  • Medical Genetics 58%

• Genomic arrays identify high-risk chronic lymphocytic leukemia with genomic complexity: A multi-center study

  Leeksma, A. C., Baliakas, P., Moysiadis, T., Puiggros, A., Plevova, K., van der Kevie-Kersemaekers, A. M., Posthuma, H., Rodriguez-Vicente, A. E., Tran, A. N., Barbany, G., Mansouri, L., Gunnarsson, R., Parker, H., van den Berg, E., Bellido, M., Davis, Z., Wall, M., Scarpelli, I., Österborg, A., Hansson, L., & 18 andraJarosova, M., Ghia, P., Poddighe, P., Espinet, B., Pospisilova, S., Tam, C., Ysebaert, L., Nguyen-Khac, F., Oscier, D., Haferlach, C., Schoumans, J., Stevens-Kroef, M., Eldering, E., Stamatopoulos, K., Rosenquist, R., Strefford, J. C., Mellink, C. & Kater, A. P., 2020, I: Haematologica. 105, 5

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • B-Cell Chronic Lymphocytic Leukemia 100%
  • Chromosome Banding 57%
  • Karyotype 38%
  • Chromosome 9p Deletion Syndrome 32%
  • Chromosome Aberrations 18%
• 2019

  Cancer chromosome breakpoints cluster in gene-rich genomic regions

  Mitelman, F., Johansson, B., Mertens, F., Schyman, T. & Mandahl, N., 2019, I: Genes Chromosomes and Cancer. 58, 3, s. 149-154

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Chromosome Breakpoints 100%
  • Multigene Family 69%
  • Chromosome Aberrations 51%
  • Neoplasms 20%
  • Chromosome Breakage 14%

• Danon disease presenting with early onset of hypertrophic cardiomyopathy and peripheral pigmentary retinal dystrophy in a female with a de novo novel mosaic mutation in the LAMP2 gene

  Meinert, M., Englund, E., Hedberg-Oldfors, C., Oldfors, A., Kornhall, B., Lundin, C. & Wittström, E., 2019 juli 2, I: Ophthalmic Genetics. 40, 3, s. 227–236 11 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Glycogen Storage Disease Type IIb 100%
  • Retinal Dystrophies 79%
  • Hypertrophic Cardiomyopathy 63%
  • Lysosomal-Associated Membrane Protein 2 40%
  • Eye 34%

• Idiopathic ventricular fibrillation – Long term prognosis in relation to clinical findings and ECG patterns in a Swedish cohort

  Chaudhry, U., Platonov, P. G., Rubulis, A., Bergfeldt, L., Jensen, S. M., Lundin, C. & Borgquist, R., 2019, I: Journal of Electrocardiology. 56, s. 46-51 6 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Paroxysmal ventricular fibrillation 100%
  • Implantable Defibrillators 55%
  • Electrocardiography 49%
  • Recurrence 13%
  • Sudden Cardiac Death 13%

• Most gene fusions in cancer are stochastic events

  Johansson, B., Mertens, F., Schyman, T., Björk, J., Mandahl, N. & Mitelman, F., 2019 sep., I: Genes Chromosomes and Cancer. 58, 9, s. 607-611 5 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Gene Fusion 100%
  • Genes 35%
  • High-Throughput Nucleotide Sequencing 33%
  • Neoplasms 28%
  • Chromosomes 27%

• Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia

  Yang, M., Vesterlund, M., Siavelis, I., Moura-Castro, L. H., Castor, A., Fioretos, T., Jafari, R., Lilljebjörn, H., Odom, D. T., Olsson, L., Ravi, N., Woodward, E. L., Harewood, L., Lehtiö, J. & Paulsson, K., 2019 apr. 3, I: Nature Communications. 10, 1, 1519.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Proteogenomics 100%
  • RNA Sequencing 99%
  • Domain Boundary 88%
  • leukemias 86%
  • Polyploidy 75%
• 2018

  Improved cytogenetic characterization and risk stratification of pediatric acute lymphoblastic leukemia using single nucleotide polymorphism array analysis: A single center experience of 296 cases

  Olsson, L., Lundin-Ström, K. B., Castor, A., Behrendtz, M., Biloglav, A., Norén-Nyström, U., Paulsson, K. & Johansson, B., 2018, I: Genes Chromosomes and Cancer. 57, 11, s. 604-607

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Cytogenetics 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 99%
  • Single Nucleotide Polymorphism 85%
  • B-Lymphoid Precursor Cells 81%
  • Pediatrics 65%

• Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases

  Li, J. F., Dai, Y. T., Lilljebjörn, H., Shen, S. H., Cui, B. W., Bai, L., Liu, Y. F., Qian, M. X., Kubota, Y., Kiyoi, H., Matsumura, I., Miyazaki, Y., Olsson, L., Tan, A. M., Ariffin, H., Chen, J., Takita, J., Yasuda, T., Mano, H., Johansson, B., & 8 andraYang, J. J., Yeoh, A. E. J., Hayakawa, F., Chen, Z., Pui, C. H., Fioretos, T., Chen, S. J. & Huang, J. Y., 2018, I: Proceedings of the National Academy of Sciences of the United States of America. 115, 50, s. E11711-E11720

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • B-Lymphoid Precursor Cells 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 81%
  • RNA Sequence Analysis 20%
  • Chromosomes 14%
  • B-Lymphocyte Subsets 11%
• 2017

  Genomic complexity and targeted genes in anaplastic thyroid cancer cell lines

  Woodward, E. L., Biloglav, A., Ravi, N., Yang, M., Ekblad, L., Wennerberg, J. & Paulsson, K., 2017 maj, I: Endocrine-Related Cancer. 24, 5, s. 209-220 12 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Anaplastic Thyroid Carcinoma 100%
  • Cell Line 41%
  • Genes 28%
  • Gene Fusion 19%
  • Mutation 19%
• 2016

  Rare novel variants in the ZIC3 gene cause X-linked heterotaxy

  Paulussen, A. D. C., Steyls, A., Vanoevelen, J., Van Tienen, F. H. J., Krapels, I. P. C., Claes, G. R. F., Chocron, S., Velter, C., Tan-Sindhunata, G. M., Lundin, C., Valenzuela, I., Nagy, B., Bache, I., Maroun, L. L., Avela, K., Brunner, H. G., Smeets, H. J. M., Bakkers, J. & Van Den Wijngaard, A., 2016 dec. 1, I: European Journal of Human Genetics. 24, 12, s. 1783-1791 9 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • X-Linked Genes 100%
  • Zinc Fingers 44%
  • Zebrafish Proteins 33%
  • Genes 23%
  • Zebrafish 19%

• The genetic landscape of paediatric de novo acute myeloid leukaemia as defined by single nucleotide polymorphism array and exon sequencing of 100 candidate genes

  Olsson, L., Zettermark, S., Biloglav, A., Castor, A., Behrendtz, M., Forestier, E., Paulsson, K. & Johansson, B., 2016 juli, I: British Journal of Haematology. 174, 2, s. 292-301

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Acute Myeloid Leukemia 100%
  • Single Nucleotide Polymorphism 88%
  • Exons 87%
  • Uniparental Disomy 76%
  • Pediatrics 67%
• 2015

  Deep sequencing and SNP array analyses of pediatric T-cell acute lymphoblastic leukemia reveal NOTCH1 mutations in minor subclones and a high incidence of uniparental isodisomies affecting CDKN2A.

  Karrman, K., Castor, A., Behrendtz, M., Forestier, E., Olsson, L., Ehinger, M., Biloglav, A., Fioretos, T., Paulsson, K. & Johansson, B., 2015, I: Journal of Hematology & Oncology. 8, 1, 42.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Uniparental Disomy 100%
  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 89%
  • High-Throughput Nucleotide Sequencing 65%
  • Single Nucleotide Polymorphism 57%
  • Pediatrics 43%
  157 Nedladdningar (Pure)

• The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.

  Paulsson, K., Lilljebjörn, H., Biloglav, A., Olsson, L., Rissler, M., Castor, A., Barbany, G., Fogelstrand, L., Nordgren, A., Sjögren, H., Fioretos, T. & Johansson, B., 2015, I: Nature Genetics. 47, 6, s. 672-676

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Polyploidy 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 77%
  • Tetrasomy 43%
  • Chromosomes 41%
  • Pediatrics 34%
  446 Nedladdningar (Pure)
• 2014

  Clinical and genetic features of pediatric acute lymphoblastic leukemia in Down syndrome in the Nordic countries

  Lundin, C., Forestier, E., Andersen, M. K., Autio, K., Barbany, G., Cavelier, L., Golovleva, I., Heim, S., Heinonen, K., Hovland, R., Johannsson, J. H., Kjeldsen, E., Nordgren, A., Palmqvist, L. & Johansson, B., 2014, I: Journal of Hematology & Oncology. 7, 32.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Scandinavian and Nordic Countries 100%
  • Down Syndrome 77%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 73%
  • Pediatrics 47%
  • B-Lymphoid Precursor Cells 8%
  151 Nedladdningar (Pure)

• Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011.

  Olsson, L., Castor, A., Behrendtz, M., Biloglav, A., Forestier, E., Paulsson, K. & Johansson, B., 2014, I: Leukemia. 28, 2, s. 302-310

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • B-Lymphoid Precursor Cells 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 81%
  • Pediatrics 53%
  • Pseudoautosomal Regions 46%
  • Uniparental Disomy 40%
  305 Nedladdningar (Pure)
• 2010

  Genetic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.

  Paulsson, K., Forestier, E., Lilljebjörn, H., Heldrup, J., Behrendtz, M., Young, B. D. & Johansson, B., 2010, I: Proceedings of the National Academy of Sciences. 107, 50, s. 21719-21724

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Polyploidy 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 77%
  • poly(A)-specific ribonuclease 38%
  • Single Nucleotide Polymorphism 33%
  • Chromosomes 31%

• Relapsed childhood high hyperdiploid acute lymphoblastic leukemia: presence of preleukemic ancestral clones and the secondary nature of microdeletions and RTK-RAS mutations.

  Davidsson, J., Paulsson, K., Lindgren, D., Lilljebjörn, H., Chaplin, T., Forestier, E., Andersen, M. K., Nordgren, A., Rosenquist, R., Fioretos, T., Young, B. D. & Johansson, B., 2010, I: Leukemia. 24, s. 924-931

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Polyploidy 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 77%
  • Clone Cells 63%
  • Recurrence 45%
  • Mutation 44%
• 2008

  Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome: an iBFM-SG study

  Forestier, E., Izraeli, S., Beverloo, B., Haas, O., Pession, A., Michalova, K., Stark, B., Harrison, C. J., Teigler-Schlegel, A. & Johansson, B., 2008, I: Blood. 111, 3, s. 1575-1583

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Cytogenetics 100%
  • Down Syndrome 73%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 69%
  • Acute Myeloid Leukemia 67%
  • Disorder 60%
• 2003

  Formation of trisomies and their parental origin in hyperdiploid childhood acute lymphoblastic leukemia.

  Paulsson, K., Panagopoulos, I., Knuutila, S., Jee, K. J., Garwicz, S., Fioretos, T., Mitelman, F. & Johansson, B., 2003, I: Blood. 102, 8, s. 3010-3015

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång
• 1997

  A breakpoint map of recurrent chromosomal rearrangements in human neoplasia

  Mitelman, F., Mertens, F. & Johansson, B., 1997 apr. 1, I: Nature Genetics. 15, 4, s. 417-474 58 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Chromosome Aberrations 100%
  • Neoplasms 55%
  • Hematologic Neoplasms 34%
  • Cytogenetics 33%
  • Chromosomes 27%