Stamcellslaboratoriet för sjukdomsmodellering i det centrala nervsystemet

Forskningsoutput

Forskningsoutput per år 1998 2015 2017 2018 2019 2020 2021 2022

• 42 Artikel i vetenskaplig tidskrift
• 5 Doktorsavhandling (sammanläggning)
• 1 Översiktsartikel

Forskningsoutput per år

Forskningsoutput per år

Sökresultat

• 2022

  Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes

  Skauli, N., Savchenko, E., Ottersen, O. P., Roybon, L. & Amiry-Moghaddam, M., 2022, I: Frontiers in Cellular Neuroscience. 16, 878154.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Aquaporin 4 100%
  • Bone Morphogenetic Proteins 89%
  • Dystrophin-Associated Protein Complex 78%
  • Astrocytes 67%
  • Aquaporins 37%

• Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties

  Azevedo, C., Teku, G., Pomeshchik, Y., Reyes, J. F., Chumarina, M., Russ, K., Savchenko, E., Hammarberg, A., Lamas, N. J., Collin, A., Gouras, G. K., Klementieva, O., Hallbeck, M., Taipa, R., Vihinen, M. & Roybon, L., 2022, I: Proceedings of the National Academy of Sciences of the United States of America. 119, 12, e2111405119.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Multiple System Atrophy 100%
  • alpha-Synuclein 90%
  • Induced Pluripotent Stem Cells 85%
  • Oligodendroglia 83%
  • Parkinson Disease 63%
• 2021

  Generation of the human pluripotent stem-cell-derived astrocyte model with forebrain identity

  Peteri, U. K., Pitkonen, J., Utami, K. H., Paavola, J., Roybon, L., Pouladi, M. A. & Castrén, M. L., 2021, I: Brain Sciences. 11, 2, 14 s., 209.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Pluripotent Stem Cells 100%
  • Prosencephalon 91%
  • Astrocytes 78%
  • 1-methylcyclopropene 18%
  • Ciliary Neurotrophic Factor 17%

• The intracellular milieu of Parkinson’s disease patient brain cells modulates alpha-synuclein protein aggregation

  Gustavsson, N., Savchenko, E., Klementieva, O. & Roybon, L., 2021, I: Acta Neuropathologica Communications. 9, 1, 153.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • alpha-Synuclein 100%
  • Parkinson Disease 69%
  • Protein Aggregates 42%
  • Brain 40%
  • Induced Pluripotent Stem Cells 37%

• TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration

  Russ, K., Teku, G., Bousset, L., Redeker, V., Piel, S., Savchenko, E., Pomeshchik, Y., Savistchenko, J., Stummann, T. C., Azevedo, C., Collin, A., Goldwurm, S., Fog, K., Elmer, E., Vihinen, M., Melki, R. & Roybon, L., 2021, I: Cell Reports. 34, 12, 108895.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Synucleins 100%
  • Astrocytes 60%
  • Respiration 54%
  • alpha-Synuclein 26%
  • Energy Metabolism 19%

• Urokinase plasminogen activator mediates changes in human astrocytes modeling fragile X syndrome

  Peteri, U. K., Pitkonen, J., de Toma, I., Nieminen, O., Utami, K. H., Strandin, T. M., Corcoran, P., Roybon, L., Vaheri, A., Ethell, I., Casarotto, P., Pouladi, M. A. & Castrén, M. L., 2021, I: GLIA. 69, 12, s. 2947-2962

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Fragile X Syndrome 100%
  • Plasminogen Activators 90%
  • Urokinase-Type Plasminogen Activator 87%
  • Astrocytes 71%
  • Neuronal Plasticity 22%
• 2020

  Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson's disease

  Brazdis, R. M., Alecu, J. E., Marsch, D., Dahms, A., Simmnacher, K., Lörentz, S., Brendler, A., Schneider, Y., Marxreiter, F., Roybon, L., Winner, B., Xiang, W. & Prots, I., 2020 apr. 1, I: Human Molecular Genetics. 29, 7, s. 1180-1191 12 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Induced Pluripotent Stem Cells 100%
  • Parkinson Disease 74%
  • Dopaminergic Neurons 67%
  • Mesencephalon 61%
  • Brain 43%

• Generation of an induced pluripotent stem cell line (CSC-32) from a patient with Parkinson's disease carrying a heterozygous variation p.A53T in the SNCA gene

  Azevedo, C., Chumarina, M., Serafimova, E., Goldwurm, S., Collin, A., Roybon, L., Savchenko, E. & Pomeshchik, Y., 2020 mars, I: Stem Cell Research. 43, 101694.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Induced Pluripotent Stem Cells 100%
  • Parkinson Disease 74%
  • Sendai virus 59%
  • Germ Layers 56%
  • Cell Line 52%

• Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies

  Pomeshchik, Y., Klementieva, O., Gil, J., Martinsson, I., Hansen, M. G., de Vries, T., Sancho-Balsells, A., Russ, K., Savchenko, E., Collin, A., Vaz, A. R., Bagnoli, S., Nacmias, B., Rampon, C., Sorbi, S., Brites, D., Marko-Varga, G., Kokaia, Z., Rezeli, M., Gouras, G. K., & 1 andraRoybon, L., 2020, I: Stem Cell Reports. 15, 1, s. 256-273 18 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Induced Pluripotent Stem Cells 100%
  • Synaptic Transmission 83%
  • Genetic Therapy 81%
  • Hippocampus 70%
  • Alzheimer Disease 68%

• NF-E2-related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin-1 mutated Alzheimer's disease astrocytes

  Oksanen, M., Hyötyläinen, I., Trontti, K., Rolova, T., Wojciechowski, S., Koskuvi, M., Viitanen, M., Levonen, A. L., Hovatta, I., Roybon, L., Lehtonen, Š., Kanninen, K. M., Hämäläinen, R. H. & Koistinaho, J., 2020 mars, I: GLIA. 68, 3, s. 589-599 11 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • human PSEN1 protein 100%
  • NF-E2-Related Factor 2 77%
  • Amyloid 51%
  • Astrocytes 50%
  • Alzheimer Disease 42%

• Unique signatures of stress-induced senescent human astrocytes

  Simmnacher, K., Krach, F., Schneider, Y., Alecu, J. E., Mautner, L., Klein, P., Roybon, L., Prots, I., Xiang, W. & Winner, B., 2020, I: Experimental Neurology. 334, 113466.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Astrocytes 100%
  • Parkinson Disease 41%
  • Rotenone 26%
  • Mesencephalon 20%
  • Neurons 12%
• 2019

  Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene

  Chumarina, M., Russ, K., Azevedo, C., Heuer, A., Pihl, M., Collin, A., Frostner, E. Å., Elmer, E., Hyttel, P., Cappelletti, G., Zini, M., Goldwurm, S. & Roybon, L., 2019 dec. 16, I: Acta Neuropathologica Communications. 7, 1, 208.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Chronic Progressive External Ophthalmoplegia 100%
  • Pluripotent Stem Cells 76%
  • Parkinsonian Disorders 71%
  • Dopaminergic Neurons 68%
  • Mesencephalon 67%

• FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes

  Savchenko, E., Teku, G. N., Boza-Serrano, A., Russ, K., Berns, M., Deierborg, T., Lamas, N. J., Wichterle, H., Rothstein, J., Henderson, C. E., Vihinen, M. & Roybon, L., 2019 juli 3, I: Scientific Reports. 9, 1, 9610.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Fibroblast Growth Factors 100%
  • Astrocytes 76%
  • Stem Cells 61%
  • Amino Acid Transport System X-AG 48%
  • Fibroblast Growth Factor 2 39%

• Generation of an induced pluripotent stem cell line (CSC-46) from a patient with Parkinson's disease carrying a novel p.R301C mutation in the GBA gene

  Gustavsson, N., Marote, A., Pomeshchik, Y., Russ, K., Azevedo, C., Chumarina, M., Goldwurm, S., Collin, A., Pinto, L., Salgado, A. J., Klementieva, O., Roybon, L. & Savchenko, E., 2019, I: Stem Cell Research. 34, 101373.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Glucosylceramidase 100%
  • Induced Pluripotent Stem Cells 78%
  • Parkinson Disease 58%
  • Cell Line 41%
  • Mutation 39%

• PARK2 mutation causes metabolic disturbances and impaired survival of human iPSC-derived neurons

  Bogetofte, H., Jensen, P., Ryding, M., Schmidt, S. I., Okarmus, J., Ritter, L., Worm, C. S., Hohnholt, M. C., Azevedo, C., Roybon, L., Bak, L. K., Waagepetersen, H., Ryan, B. J., Wade-Martins, R., Larsen, M. R. & Meyer, M., 2019 juli 5, I: Frontiers in Cellular Neuroscience. 13, 297.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Neurons 100%
  • Mutation 90%
  • Survival 90%
  • Proteomics 74%
  • parkin protein 69%
• 2018

  Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition

  Siebzehnrübl, F. A., Raber, K. A., Urbach, Y. K., Schulze-Krebs, A., Canneva, F., Moceri, S., Habermeyer, J., Achoui, D., Gupta, B., Steindler, D. A., Stephan, M., Nguyen, H. P., Bonin, M., Riess, O., Bauer, A., Aigner, L., Couillard-Despres, S., Paucar, M. A., Svenningsson, P., Osmand, A., & 11 andraAndreew, A., Zabel, C., Weiss, A., Kuhn, R., Moussaoui, S., Blockx, I., Van der Linden, A., Cheong, R. Y., Roybon, L., Petersén, Å. & Von Hörsten, S., 2018 sep. 11, I: Proceedings of the National Academy of Sciences of the United States of America. 115, 37, s. E8765-E8774

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Huntington Disease 100%
  • Psychological Inhibition 73%
  • Histone Deacetylase Inhibitors 42%
  • Panobinostat 28%
  • Stem Cells 26%

• Generation of a human induced pluripotent stem cell line (CSC-40) from a Parkinson's disease patient with a PINK1 p.Q456X mutation

  Russ, K., Marote, A., Savchenko, E., Collin, A., Goldwurm, S., Pomeshchik, Y. & Roybon, L., 2018 mars 1, I: Stem Cell Research. 27, s. 61-64 4 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Induced Pluripotent Stem Cells 100%
  • Parkinson Disease 74%
  • Cell Line 52%
  • PTEN-induced putative kinase 50%
  • Mutation 49%

• Generation of a human induced pluripotent stem cell line (CSC-42) from a patient with sporadic form of Parkinson's disease

  Savchenko, E., Marote, A., Russ, K., Collin, A., Goldwurm, S., Roybon, L. & Pomeshchik, Y., 2018 mars 1, I: Stem Cell Research. 27, s. 78-81 4 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Induced Pluripotent Stem Cells 100%
  • Parkinson Disease 74%
  • Fibroblasts 65%
  • Sendai virus 59%
  • Germ Layers 56%

• Generation of an induced pluripotent stem cell line (CSC-41) from a Parkinson's disease patient carrying a p.G2019S mutation in the LRRK2 gene

  Marote, A., Pomeshchik, Y., Collin, A., Goldwurm, S., Lamas, N. J., Pinto, L., Salgado, A. J. & Roybon, L., 2018 apr. 1, I: Stem Cell Research. 28, s. 44-47 4 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Induced Pluripotent Stem Cells 100%
  • Leucine 90%
  • Parkinson Disease 74%
  • Phosphotransferases 68%
  • Cell Line 52%

• Generation of an induced pluripotent stem cell line (CSC-44) from a Parkinson's disease patient carrying a compound heterozygous mutation (c.823C > T and EX6 del) in the PARK2 gene

  Marote, A., Pomeshchik, Y., Goldwurm, S., Collin, A., Lamas, N. J., Pinto, L., Salgado, A. J. & Roybon, L., 2018 mars 1, I: Stem Cell Research. 27, s. 90-94 5 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Induced Pluripotent Stem Cells 100%
  • Parkinson Disease 74%
  • Cell Line 52%
  • Mutation 49%
  • Sendai virus 39%

• Generation of an integration-free induced pluripotent stem cell line (CSC-43J) from a patient with sporadic Parkinson's disease

  Marote, A., Pomeshchik, Y., Goldwurm, S., Collin, A., Lamas, N. J., Pinto, L., Salgado, A. J. & Roybon, L., 2018 mars 1, I: Stem Cell Research. 27, s. 82-85 4 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Induced Pluripotent Stem Cells 100%
  • Parkinson Disease 74%
  • Cell Line 52%
  • Sendai virus 39%
  • Germ Layers 37%

• Parkin absence accelerates microtubule aging in dopaminergic neurons

  Cartelli, D., Amadeo, A., Calogero, A. M., Casagrande, F. V. M., De Gregorio, C., Gioria, M., Kuzumaki, N., Costa, I., Sassone, J., Ciammola, A., Hattori, N., Okano, H., Goldwurm, S., Roybon, L., Pezzoli, G. & Cappelletti, G., 2018 jan., I: Neurobiology of Aging. 61, s. 66-74

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Dopaminergic Neurons 100%
  • Microtubules 93%
  • Mitochondria 33%
  • Knockout Mice 25%
  • Parkinson Disease 22%
• 2017

  Amplifying mitochondrial function rescues adult neurogenesis in a mouse model of Alzheimer's disease

  Richetin, K., Moulis, M., Millet, A., Arràzola, M. S., Andraini, T., Hua, J., Davezac, N., Roybon, L., Belenguer, P., Miquel, M. C. & Rampon, C., 2017 juni 1, I: Neurobiology of Disease. 102, s. 113-124 12 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Neurogenesis 100%
  • Alzheimer Disease 73%
  • Dendritic Spines 68%
  • Neurons 58%
  • Mitochondria 31%

• Derivation of mouse embryonic stem cell lines from tyrosine hydroxylase reporter mice crossed with a human SNCA transgenic mouse model of Parkinson's disease

  Chumarina, M., Azevedo, C., Bigarreau, J., Vignal, C., Kim, K. S., Li, J-Y. & Roybon, L., 2017 mars 1, I: Stem Cell Research. 19, s. 17-20 4 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Mouse Embryonic Stem Cells 100%
  • Tyrosine 3-Monooxygenase 89%
  • Green Fluorescent Proteins 87%
  • human SNCA protein 85%
  • Transgenic Mice 72%

• Differential alteration of hippocampal function and plasticity in females and males of the APPxPS1 mouse model of Alzheimer's disease

  Richetin, K., Petsophonsakul, P., Roybon, L., Guiard, B. P. & Rampon, C., 2017 sep. 1, I: Neurobiology of Aging. 57, s. 220-231 12 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Alzheimer Disease 100%
  • Memory 70%
  • Memory Disorders 68%
  • Neurogenesis 68%
  • mouse presenilin 1 56%

• Human astrocytes transfer aggregated alpha-synuclein via tunneling nanotubes

  Rostami, J., Holmqvist, S., Lindström, V., Sigvardson, J., Westermark, G. T., Ingelsson, M., Bergström, J., Roybon, L. & Erlandsson, A., 2017 dec. 6, I: Journal of Neuroscience. 37, 49, s. 11835-11853 19 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Nanotubes 100%
  • alpha-Synuclein 87%
  • Astrocytes 67%
  • Parkinson Disease 20%
  • Mitochondria 20%

• Memory formation orchestrates the wiring of adult-born hippocampal neurons into brain circuits

  Petsophonsakul, P., Richetin, K., Andraini, T., Roybon, L. & Rampon, C., 2017, I: Brain Structure and Function. 222, 6, s. 2585-2601

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Memory 100%
  • Neurons 84%
  • Brain 67%
  • Dendritic Spines 41%
  • Spine 26%

• Reporting on methods to generate and purify rodent and human oligodendrocytes from different sources

  Djelloul, M., Azevedo, C., Pomeshchik, Y., Hammarberg, A. & Roybon, L., 2017 apr. 1, I: Stem Cell Research. 20, s. 58-66 9 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Oligodendroglia 100%
  • Rodentia 75%
  • Oligodendrocyte Precursor Cells 40%
  • Multiple System Atrophy 40%
  • Pluripotent Stem Cells 35%
• 2016

  Label-free concentration of viable neurons, hESCs and cancer cells by means of acoustophoresis.

  Castro Zalis, M., Reyes, J. F., Augustsson, P., Holmqvist, S., Roybon, L., Laurell, T. & Deierborg, T., 2016, I: Integrative Biology. 8, 3, s. 332-340 9 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Human Embryonic Stem Cells 100%
  • Cell Death 88%
  • Neurons 51%
  • Staurosporine 41%
  • Protein Kinase Inhibitor 41%

• α-Synuclein is a Novel Microtubule Dynamase

  Cartelli, D., Aliverti, A., Barbiroli, A., Santambrogio, C., Ragg, E. M., Casagrande, F. V. M., Cantele, F., Beltramone, S., Marangon, J., De Gregorio, C., Pandini, V., Emanuele, M., Chieregatti, E., Pieraccini, S., Holmqvist, S., Bubacco, L., Roybon, L., Pezzoli, G., Grandori, R., Arnal, I., & 1 andraCappelletti, G., 2016 sep. 15, I: Scientific Reports. 6, 33289.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Synucleins 100%
  • Microtubules 64%
  • Tubulin 39%
  • Parkinson Disease Associated Proteins 13%
  • Sexual Partners 8%
• 2015

  Alpha-Synuclein Expression in the Oligodendrocyte Lineage: an In Vitro and In Vivo Study Using Rodent and Human Models.

  Djelloul, M., Holmqvist, S., Boza Serrano, A., Azevedo, C., Yeung, M. S., Goldwurm, S., Frisén, J., Deierborg, T. & Roybon, L., 2015, I: Stem Cell Reports. 5, 2, s. 174-184

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • alpha-Synuclein 100%
  • Oligodendroglia 91%
  • Rodentia 69%
  • Multiple System Atrophy 36%
  • In Vitro Techniques 36%
  347 Nedladdningar (Pure)

• Generation of human pluripotent stem cell reporter lines for the isolation of and reporting on astrocytes generated from ventral midbrain and ventral spinal cord neural progenitors.

  Holmqvist, S., Brouwer, M., Djelloul, M., Diaz, A. G., Devine, M. J., Hammarberg, A., Fog, K., Kunath, T. & Roybon, L., 2015, I: Stem Cell Research. 15, 1, s. 203-220

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Pluripotent Stem Cells 100%
  • Mesencephalon 88%
  • Astrocytes 78%
  • Spinal Cord 70%
  • Cell Line 50%
  245 Nedladdningar (Pure)

• Genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of Alzheimer's disease.

  Richetin, K., Leclerc, C., Toni, N., Gallopin, T., Pech, S., Roybon, L. & Rampon, C., 2015, I: Brain. 138, s. 440-455

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Alzheimer Disease 100%
  • Memory 94%
  • Neurons 79%
  • Neurogenesis 68%
  • Dendritic Spines 19%

• Leptin is required for hypothalamic regulation of miRNAs targeting POMC 3'UTR.

  Derghal, A., Djelloul, M., Airault, C., Pierre, C., Dallaporta, M., Troadec, J-D., Tillement, V., Tardivel, C., Bariohay, B., Trouslard, J. & Mounien, L., 2015, I: Frontiers in Cellular Neuroscience. 9, 172.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Pro-Opiomelanocortin 100%
  • 3' Untranslated Regions 80%
  • Leptin 77%
  • MicroRNAs 65%
  • Hypothalamus 45%
  176 Nedladdningar (Pure)

• The Origin, Development and Molecular Diversity of Rodent Olfactory Bulb Glutamatergic Neurons Distinguished by Expression of Transcription Factor NeuroD1.

  Roybon, L., Mastracci, T. L., Li, J., Stott, S., Leiter, A. B., Sussel, L., Brundin, P. & Li, J-Y., 2015, I: PLoS ONE. 10, 6, e0128035.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Olfactory Bulb 100%
  • Rodentia 72%
  • Transcription Factors 65%
  • Neurons 53%
  • Basic Helix-Loop-Helix Transcription Factors 20%
  183 Nedladdningar (Pure)
• 2014

  Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats.

  Holmqvist, S., Chutna, O., Bousset, L., Aldrin-Kirk, P., Li, W., Björklund, T., Wang, Z-Y., Roybon, L., Melki, R. & Li, J-Y., 2014, I: Acta Neuropathologica. 128, 6, s. 805-820

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Synucleins 100%
  • Gastrointestinal Tract 57%
  • Pathology 41%
  • Lewy Bodies 38%
  • Brain 32%
  618 Nedladdningar (Pure)

• Gene Profiling of Human Induced Pluripotent Stem Cell-Derived Astrocyte Progenitors Following Spinal Cord Engraftment.

  Haidet-Phillips, A. M., Roybon, L., Gross, S. K., Tuteja, A., Donnelly, C. J., Richard, J-P., Ko, M., Sherman, A., Eggan, K., Henderson, C. E. & Maragakis, N. J., 2014, I: Stem cells translational medicine. 3, 5, s. 575-585

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Induced Pluripotent Stem Cells 100%
  • Astrocytes 81%
  • Spinal Cord 72%
  • Genes 35%
  • Human Embryonic Stem Cells 13%

• Novel AAV-Based Rat Model of Forebrain Synucleinopathy Shows Extensive Pathologies and Progressive Loss of Cholinergic Interneurons.

  Aldrin-Kirk, P., Davidsson, M., Holmqvist, S., Li, J-Y. & Björklund, T., 2014, I: PLoS ONE. 9, 7, e100869.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Synucleins 100%
  • Synucleinopathies 92%
  • Prosencephalon 70%
  • Interneurons 69%
  • Cholinergic Agents 61%
  324 Nedladdningar (Pure)
• 2013

  Modifications of Hippocampal Circuits and Early Disruption of Adult Neurogenesis in the Tg2576 Mouse Model of Alzheimer's Disease

  Krezymon, A., Richetin, K., Halley, H., Roybon, L., Lassalle, J-M., Frances, B., Verret, L. & Rampon, C., 2013, I: PLoS ONE. 8, 9

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Neurogenesis 100%
  • Alzheimer Disease 73%
  • Dentate Gyrus 41%
  • Cognitive Dysfunction 30%
  • Calbindins 25%
  198 Nedladdningar (Pure)

• NGF rescues hippocampal cholinergic neuronal markers, restores neurogenesis, and improves the spatial working memory in a mouse model of Huntington's Disease

  Zhang, H., Petit, G., Gaughwin, P., Hansen, C., Ranganathan, S., Zuo, X., Smith, R., Roybon, L., Brundin, P., Mobley, W. C. & Li, J-Y., 2013 jan. 1, I: Journal of Huntington's disease. 2, 1, s. 69-82

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
• 2009

  Absence of striatal newborn neurons with mature phenotype following defined striatal and cortical excitotoxic brain injuries.

  Deierborg, T., Staflin, K., Pesic, J., Roybon, L., Brundin, P. & Lundberg, C., 2009, I: Experimental Neurology. 219, s. 363-367

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Lateral Ventricles 100%
  • Corpus Striatum 88%
  • Brain Injuries 87%
  • Neurogenesis 72%
  • Neurons 55%
• 1998

  Human eosinophils express, relative to other circulating leukocytes, large amounts of secretory 14-kD phospholipase A2

  Blom, M., Tool, A. T. J., Wever, P. C., Wolbink, G. J., Brouwer, M. C., Calafat, J., Egesten, A., Knol, E. F., Hack, C. E., Roos, D. & Verhoeven, A. J., 1998 apr. 15, I: Blood. 91, 8, s. 3037-3043 7 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Leukotriene C4 100%
  • Phospholipases A2 77%
  • Mammalian Cell 67%
  • Eosinophils 63%
  • Leukocytes 51%