Pediatrisk hematologi

Forskningsoutput

Forskningsoutput per år 1978 1992 1994 1999 2005 2008 2010 2011 2012 2013 2014 2015 2016 2017 2020 2022 2023

• 172 Artikel i vetenskaplig tidskrift
• 30 Översiktsartikel
• 16 Letter
• 10 Publicerat konferensabstract
• 25 Mer
  • 8 Kapitel samlingsverk
  • 7 Debate/Note/Editorial
  • 4 Artikel i facktidskrift eller populärpress
  • 3 Bok
  • 1 Konferenspaper i proceeding
  • 1 Special-/temanummer av tidskrift (redaktör)
  • 1 Doktorsavhandling (sammanläggning)

Forskningsoutput per år

Forskningsoutput per år

Sökresultat

• 2023

  BAY 81-8973 Efficacy and Safety in Previously Untreated and Minimally Treated Children with Severe Hemophilia A: The LEOPOLD Kids Trial

  Ljung, R., Chan, A. K. C., Glosli, H., Afonja, O., Becker, B., Tseneklidou-Stoeter, D., Mancuso, M. E., Saulyte-Trakymiene, S. & Kenet, G., 2023 jan., I: Thrombosis and Haemostasis. 123, 1, s. 27-39

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • human F8 protein 100%
  • Hemophilia A 74%
  • Safety 38%
  • Child 28%
  • Immune Tolerance 24%

• No difference in quality of life between persons with severe haemophilia A and B

  Kihlberg, K., Baghaei, F., Bruzelius, M., Funding, E., Andre Holme, P., Lassila, R., Nummi, V., Ranta, S., Gretenkort Andersson, N., Berntorp, E. & Astermark, J., 2023, (E-pub ahead of print) I: Haemophilia.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Hemophilia B 100%
  • Hemophilia A 83%
  • Quality of Life 47%
  • Joints 16%
  • Health 11%
• 2022

  A survey on thromboprophylaxis and coagulation assessment in children and young adults with acute lymphoblastic leukaemia (ALL) in the Nordic and Baltic countries: Different practices of assessment and management

  Andersson, N. G., Rathe, M., Mølle, I., Jarvis, K. B., Hoffmann, M., Huurre, A., Joelsson, J., Albertsen, B. K., Lohi, O., Långström, S., Overgaard, U., Saulyte Trakymiene, S., Vepsäläinen, K., Vogt, H. & Ranta, S., 2022 okt., I: British Journal of Haematology. 199, 1, s. 117-121 5 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Scandinavian and Nordic Countries 100%
  • Practice Management 88%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 73%
  • Young Adult 60%
  • Pediatrics 47%

• Factor IX antibodies and tolerance in hemophilia B in the Nordic countries - The impact of F9 variants and complications

  Kihlberg, K., Baghaei, F., Bruzelius, M., Funding, E., Holme, P. A., Lassila, R., Martin, M., Nummi, V., Ranta, S., Strandberg, K., Andersson, N. G., Berntorp, E. & Astermark, J., 2022 sep., I: Thrombosis Research. 217, s. 22-32

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Hemophilia B 100%
  • Scandinavian and Nordic Countries 99%
  • Factor IX 96%
  • Immune Tolerance 89%
  • Antibodies 40%

• Haemophilia A and B - evaluation of the Swedish prophylactic regimen by magnetic resonance imaging

  Lundin, B., Baghaei, F., Holmström, M., Petrini, P., Müller, G., Månsson, S. & Ljung, R., 2022 dec. 5, (E-pub ahead of print) I: Haemophilia.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Hemophilia B 100%
  • Hemophilia A 83%
  • Joints 52%
  • Magnetic Resonance Imaging 48%
  • Joint Diseases 30%

• Intracranial Hemorrhages in Neonates: Incidence, Risk Factors and Treatment

  Andersson, N. G. & Kenet, G., 2022, (E-pub ahead of print) I: Seminars in Thrombosis and Hemostasis.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Intracranial Hemorrhages 100%
  • Hemorrhage 57%
  • Incidence 43%
  • Congenital, Hereditary, and Neonatal Diseases and Abnormalities 36%
  • Hemophilia A 33%

• Long-term joint outcomes in adolescents with moderate or severe haemophilia A

  Schmidt, D. E., Michalopoulou, A., Fischer, K., Motwani, J., Andersson, N. G., Pergantou, H., Ranta, S. & the PedNet Study Group, 2022, I: Haemophilia. 28, 6 , s. 1054-1061

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Hemophilia A 100%
  • Joints 43%
  • Physical Examination 23%
  • Adolescent Health 8%
  • Patents 8%

• Primary prophylaxis in children with severe haemophilia A and B-Implementation over the last 20 years as illustrated in real-world data in the PedNet cohorts

  Ljung, R., de Kovel, M., van den Berg, H. M. & PedNet Study Group, 2022 dec. 26, (E-pub ahead of print) I: Haemophilia.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Hemophilia B 100%
  • Hemophilia A 83%
  • Child 32%
  • Joints 15%
  • Publications 6%

• Silent variant in F8:c.222G>T (p.Thr74Thr) causes a partial exon skipping in a patient with mild hemophilia A

  Letelier, A., Ljung, R., Olsson, A. & Andersson, N. G., 2022 jan., I: Molecular Genetics & Genomic Medicine. 10, 1, e1856.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Hemophilia A 100%
  • Exons 73%
  • Type 1 von Willebrand Disease 47%
  • Hemorrhage 19%
  • Genetic Testing 15%
• 2021

  Droplet digital PCR and mile-post analysis for the detection of F8 int1h inversions

  Manderstedt, E., Lind-Halldén, C., Ljung, R., Astermark, J. & Halldén, C., 2021, I: Journal of Thrombosis and Haemostasis. 19, 3, s. 732-737

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Polymerase Chain Reaction 100%
  • DNA 94%
  • Mothers 53%
  • Hemophilia A 47%
  • Mutation 47%

• Inhibitor incidence in an unselected cohort of previously untreated patients with severe haemophilia B: a PedNet study

  Male, C., Andersson, N. G., Rafowicz, A., Liesner, R., Kurnik, K., Fischer, K., Platokouki, H., Santagostino, E., Chambost, H., Nolan, B., Königs, C., Kenet, G., Ljung, R., van den Berg, M. & PedNet Study Group, 2021, I: Haematologica. 106, 1, s. 123-129

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Hemophilia B 100%
  • Incidence 35%
  • Hypersensitivity 22%
  • Nonsense Codon 21%
  • Factor IX 12%

• Principles of Care for Acquired Hemophilia

  Dolan, G., Benson, G., Bowyer, A., Eichler, H., Hermans, C., Jiménez-Yuste, V., Ljung, R., Pollard, D., Santagostino, E. & Zupančić Šalek, S., 2021 juni 1, I: European Journal of Haematology. 106, 6, s. 762-773 12 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Acquired Factor 8 deficiency 100%
  • Hemophilia A 67%
  • Hemorrhage 11%
  • Physicians 10%
  • Delivery of Health Care 10%
• 2020

  Continued benefit demonstrated with BAY 81-8973 prophylaxis in previously treated children with severe haemophilia A: Interim analysis from the LEOPOLD Kids extension study

  Kenet, G., Ljung, R., Rusen, L., Kerlin, B. A., Blanchette, V., Saulytė Trakymienė, S., Uscatescu, V., Beckmann, H., Tseneklidou-Stoeter, D. & Church, N., 2020 maj, I: Thrombosis Research. 189, s. 96-101 6 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • human F8 protein 100%
  • Hemophilia A 74%
  • Child 28%
  • Pediatrics 15%
  • Safety 9%

• Detection of F8 int22h inversions using digital droplet PCR and mile-post assays

  Manderstedt, E., Lind-Halldén, C., Ljung, R., Astermark, J. & Halldén, C., 2020 maj, I: Journal of Thrombosis and Haemostasis. 18, 5, s. 1039-1049 11 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Polymerase Chain Reaction 100%
  • Introns 65%
  • Hemophilia A 38%
  • DNA 37%
  • Chromosomes 26%

• Detection of mosaics in hemophilia A by deep Ion Torrent sequencing and droplet digital PCR

  Manderstedt, E., Nilsson, R., Ljung, R., Lind-Halldén, C., Astermark, J. & Halldén, C., 2020 okt., I: Research and practice in thrombosis and haemostasis. 4, 7, s. 1121-1130 10 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Mosaicism 100%
  • Hemophilia A 91%
  • High-Throughput Nucleotide Sequencing 77%
  • Polymerase Chain Reaction 48%
  • Mothers 38%

• Genetic screening of children with suspected inherited bleeding disorders

  Andersson, N., Rossing, M., Fager Ferrari, M., Gabrielaite, M., Leinøe, E., Ljung, R., Mårtensson, A., Norström, E. & Zetterberg, E., 2020, I: Haemophilia. 26, 2, s. 314-324 11 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Genetic Testing 100%
  • Hemorrhage 62%
  • Child 42%
  • Thrombocytopenia 40%
  • Incidental Findings 12%

• Genome-wide association meta-analysis of single-nucleotide polymorphisms and symptomatic venous thromboembolism during therapy for acute lymphoblastic leukemia and lymphoma in caucasian children

  Mateos, M. K., Tulstrup, M., Quinn, M. C. J., Tuckuviene, R., Marshall, G. M., Gupta, R., Mayoh, C., Wolthers, B. O., Barbaro, P. M., Ruud, E., Sutton, R., Huttunen, P., Revesz, T., Trakymiene, S. S., Barbaric, D., Tedgård, U., Giles, J. E., Alvaro, F., Jonsson, O. G., Mechinaud, F., & 8 andraSaks, K., Catchpoole, D., Kotecha, R. S., Dalla-Pozza, L., Chenevix-Trench, G., Trahair, T. N., Macgregor, S. & Schmiegelow, K., 2020 maj 19, I: Cancers. 12, 5, 1285.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Venous Thromboembolism 100%
  • Genome-Wide Association Study 96%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 90%
  • Single Nucleotide Polymorphism 77%
  • Meta-Analysis 69%

• Novel F8 and F9 gene variants from the PedNet Hemophilia Registry classified according to ACMG/AMP guidelines

  Andersson, N. G., Labarque, V., Letelier, A., Mancuso, M. E., Bührlen, M., Fischer, K., Kartal-Kaess, M., Koskenvuo, M., Mikkelsen, T., Ljung, R. & PedNet Study Group, 2020 dec., I: Human Mutation. 41, 12, s. 2058-2072 15 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Medical Genetics 100%
  • Hemophilia A 83%
  • Adenosine Monophosphate 82%
  • Genomics 75%
  • Registries 58%

• Parenting stress and its correlates in an infant mental health unit: a cross-sectional study

  Tedgård, E., Tedgård, U., Råstam, M. & Johansson, B. A., 2020, I: Nordic Journal of Psychiatry. 74, 1, s. 30-39

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Infant Health 100%
  • Parenting 92%
  • Mental Health 64%
  • Parents 62%
  • Cross-Sectional Studies 53%

• Registries and databases: A European perspective

  Ljung, R. C. R., 2020 apr., I: Haemophilia. 26 , Suppl 3, s. 26-28 2 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Registries 100%
  • Databases 76%
  • Data Accuracy 44%
  • Datasets 33%
  • Cohort Studies 28%

• WFH Guidelines for the Management of Hemophilia, 3rd edition

  Srivastava, A., Santagostino, E., Dougall, A., Kitchen, S., Sutherland, M., Pipe, S. W., Carcao, M., Mahlangu, J., Ragni, M. V., Windyga, J., Llinás, A., Goddard, N. J., Mohan, R., Poonnoose, P. M., Feldman, B. M., Lewis, S. Z., van den Berg, H. M., Pierce, G. F., Ljung, R. & WFH Guidelines for the Management of Hemophilia panelists and co-authors, 2020 aug. 1, I: Haemophilia. 26, S6, s. 1-158

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång
• 2019

  Mode of delivery in hemophilia: Vaginal delivery and Cesarean section carry similar risks for intracranial hemorrhages and other major bleeds

  Andersson, N. G., Chalmers, E. A., Kenet, G., Ljung, R., Mäkipernaa, A., Chambost, H. & PedNet Haemophilia Research Foundation, 2019, I: Haematologica. 104, 10, s. 2100-2106 7 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Hemophilia A 100%
  • Intracranial Hemorrhages 99%
  • Cesarean Section 83%
  • Newborn Infant 29%
  • Multicenter Studies 10%

• Recombinant factor VIII products and inhibitor development in previously untreated patients with severe haemophilia A: Combined analysis of three studies

  Volkers, P., Hanschmann, K-M., Calvez, T., Chambost, H., Collins, P. W., Demiguel, V., Hart, D. P., Hay, C. R. M., Goudemand, J., Ljung, R., Palmer, B. P., Santagostino, E., van Hardeveld, E. M., van den Berg, M. & Keller-Stanislawski, B., 2019, I: Haemophilia. 25, 3, s. 398-407

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hemophilia A 100%
  • Factor VIII 99%
  • Isoantibodies 16%
  • Immunoglobulin G 9%
  • Cohort Studies 8%
• 2018

  Prevention and Management of Bleeding Episodes in Children with Hemophilia

  Ljung, R. C. R., 2018, I: Pediatric Drugs. 20, 5, s. 455-464

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Hemophilia A 100%
  • Factor VIII 99%
  • prothrombin complex concentrates 63%
  • Hemophilia B 59%
  • Hemorrhage 57%

• SAMD9 and SAMD9L in inherited predisposition to ataxia, pancytopenia, and myeloid malignancies

  Davidsson, J., Puschmann, A., Tedgård, U., Bryder, D., Nilsson, L. & Cammenga, J., 2018 maj, I: Leukemia. 32, 5, s. 1106-1115

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Pancytopenia 100%
  • Ataxia 84%
  • Chromosomes, Human, Pair 7 51%
  • Germ-Line Mutation 45%
  • Mutation 44%
• 2017

  Ataxia-pancytopenia syndrome with SAMD9L mutations

  Gorcenco, S., Komulainen-Ebrahim, J., Nordborg, K., Suo-Palosaari, M., Andréasson, S., Krüger, J., Nilsson, C., Kjellström, U., Rahikkala, E., Turkiewicz, D., Karlberg, M., Nilsson, L., Cammenga, J., Tedgård, U., Davidsson, J., Uusimaa, J. & Puschmann, A., 2017 okt., I: Neurology: Genetics. 3, 5, 7 s., e183.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Myelocerebellar Disorder 100%
  • Pancytopenia 54%
  • Ataxia 46%
  • Glare 41%
  • Nervous System 35%

• Beyond stopping the bleed: short-term episodic prophylaxis with recombinant activated factor FVII in haemophilia patients with inhibitors.

  Šalek, S. Z., Auerswald, G., Benson, G., Dolan, G., Duffy, A., Hermans, C., Jiménez-Yuste, V., Ljung, R., Morfini, M., Santagostino, E. & Lambert, T., 2017, I: Blood Transfusion. 15, s. 77-84

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Hemophilia A 100%
  • recombinant FVIIa 70%
  • Joint Diseases 27%
  • Hemarthrosis 18%
  • Factor VIIa 17%

• Discrepancies between the one-stage clotting assay and the chromogenic assay in haemophilia B

  Kihlberg, K., Strandberg, K., Rosén, S., Ljung, R. & Astermark, J., 2017, I: Haemophilia. 23, 4, s. 620-627

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hemophilia B 100%
  • Hemophilia A 18%
  • Factor IX 10%
  • Hemorrhage 10%
  • Factor VIII 9%

• Effect of late prophylaxis in hemophilia on joint status: A randomized trial

  Manco-Johnson, M. J., Lundin, B., Funk, S., Peterfy, C., Raunig, D., Werk, M., Kempton, C. L., Reding, M. T., Goranov, S., Gercheva, L., Rusen, L., Uscatescu, M. V., Pierdominici, M., Engelen, S., Pocoski, J., Walker, D. & Hong, W., 2017 nov., I: Journal of Thrombosis and Haemostasis. 15, 11, s. 2115-2124

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hemophilia A 100%
  • Joint Diseases 75%
  • Joints 62%
  • Hemorrhage 38%
  • Least-Squares Analysis 32%

• Endovascular treatment of vein of Galen aneurysmal malformation using rapid ventricular pacing: A case report

  Ramgren, B., Rask, O., Gelberg, J., Liuba, P., Undrén, P. & Wassélius, J., 2017 feb. 1, I: Interventional Neuroradiology. 23, 1, s. 97-101

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Vein of Galen Malformations 100%
  • Fistula 53%
  • Endovascular Procedures 35%
  • Therapeutics 9%

• Intracranial haemorrhage in children and adolescents with severe haemophilia A or B - the impact of prophylactic treatment

  Gretenkort Andersson, N., Auerswald, G., Barnes, C., Carcao, M., Dunn, A. L., Fijnvandraat, K., Hoffmann, M., Kavakli, K., Kenet, G., Kobelt, R., Kurnik, K., Liesner, R., Mäkipernaa, A., Manco-Johnson, M. J., Mancuso, M. E., Molinari, A. C., Nolan, B., Perez Garrido, R., Petrini, P., Platokouki, H. E., & 3 andraShapiro, A. D., Wu, R. & Ljung, R., 2017, I: British Journal of Haematology. 179, 2, s. 298-307

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hemophilia B 100%
  • Hemophilia A 83%
  • Intracranial Hemorrhages 83%
  • Child 32%
  • Therapeutics 12%

• Primary prophylaxis in haemophilia care: Guideline update 2016

  Fischer, K. & Ljung, R., 2017, I: Blood Cells, Molecules, and Diseases. 67, s. 81-85

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hemophilia A 100%
  • Factor VIII 99%
  • Compliance 79%
  • Half-Life 78%
  • Organizations 74%
• 2016

  BAY 81-8973 safety and efficacy for prophylaxis and treatment of bleeds in previously treated children with severe haemophilia A: results of the LEOPOLD Kids Trial.

  Ljung, R., Kenet, G., Mancuso, M. E., Kaleva, V., Rusen, L., Tseneklidou-Stoeter, D., Michaels, L. A., Shah, A., Hong, W. & Maas Enriquez, M., 2016, I: Haemophilia. 22, 3, s. 354-360

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • human F8 protein 100%
  • Hemophilia A 74%
  • Factor VIII 74%
  • Safety 38%
  • Sucrose 32%

• Breath-holding spells occur disproportionately more often in children with transient erythroblastopenia

  Schmidt, S. H., Tedgård, U. & Pronk, K-J., 2016 sep., I: Acta Pædiatrica. 105, 9, s. 1088-1093

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Transient erythroblastopenia of childhood 100%
  • Breath Holding 74%
  • Child 22%
  • Anemia 22%
  • Sweden 5%

• Evaluating outcome of prophylaxis in haemophilia: objective and self-reported instruments should be combined.

  Fischer, K., Nijdam, A., Holmström, M., Petrini, P., Ljung, R., van der Schouw, Y. T. & Berntorp, E., 2016, I: Haemophilia.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hemophilia A 100%
  • Health Care Outcome Assessment 57%

• Increased inhibitor incidence in severe haemophilia A since 1990 attributable to more low titre inhibitors

  van den Berg, H. M., Hashemi, S. M., Fischer, K., Petrini, P., Ljung, R., Rafowicz, A., Carcao, M., Auerswald, G., Kurnik, K., Kenet, G. & Santagostino, E., 2016 apr. 1, I: Thrombosis and Haemostasis. 115, 4, s. 729-737 9 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hemophilia A 100%
  • Incidence 43%
  • Parturition 13%
  • Therapeutics 3%

• Inhibitor development in previously untreated patients with severe haemophilia A: a nationwide multicentre study in Finland

  Vepsäläinen, K., Lassila, R., Arola, M., Huttunen, P., Koskinen, S., Ljung, R., Lähteenmäki, P., Möttönen, M. & Riikonen, P., 2016 sep. 1, I: Haemophilia. 22, 5, s. 721-729 9 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hemophilia A 100%
  • Finland 95%
  • Multicenter Studies 76%
  • Incidence 25%
  • Neutralizing Antibodies 17%

• Origin of mutation in sporadic cases of severe haemophilia A in Sweden.

  Mårtensson, A., Ivarsson, S., Letelier, A., Manderstedt, E., Halldén, C. & Ljung, R., 2016, I: Clinical Genetics. 90, 1, s. 63-68

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Mosaicism 100%
  • Hemophilia A 91%
  • Sweden 79%
  • Mothers 51%
  • Mutation 45%

• Phenotype and genotype comparisons in carriers of haemophilia A

  Olsson, A., Ljung, R., Hellgren, M., Berntorp, E. & Baghaei, F., 2016 maj, I: Haemophilia. 22, 3, s. 235–237

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

• Potential biomarkers of haemophilic arthropathy: correlations with compatible additive magnetic resonance imaging scores

  Oldenburg, J., Zimmermann, R., Katsarou, O., Zanon, E., Kellermann, E., Lundin, B. & Ellinghaus, P., 2016 sep. 1, I: Haemophilia. 22, 5, s. 760-764 5 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Joint Diseases 100%
  • Magnetic Resonance Imaging 60%
  • Biomarkers 59%
  • Cartilage Oligomeric Matrix Protein 34%
  • Tissue Inhibitor of Metalloproteinase-1 27%

• Prospective study of thromboembolism in 1038 children with acute lymphoblastic leukemia - a Nordic Society of Pediatric Hematology and Oncology (NOPHO) study.

  Tuckuviene, R., Ranta, S., Albertsen, B. K., Andersson, N. G., Bendtsen, M. D., Frisk, T., Gunnes, M. W., Helgestad, J., Heyman, M. M., Jonsson, O. G., Mäkipernaa, A., Pruunsild, K., Tedgård, U., Trakymiene, S. S. & Ruud, E., 2016, I: Journal of Thrombosis and Haemostasis. 14, 3, s. 485-494

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Thromboembolism 100%
  • Hematology 94%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 86%
  • Pediatrics 56%
  • Prospective Studies 56%
• 2015

  How to achieve full prophylaxis in young boys with severe haemophilia A: different regimens and their effect on early bleeding and venous access

  Nijdam, A., Kurnik, K., Liesner, R., Ljung, R., Nolan, B., Petrini, P. & Fischer, K., 2015, I: Haemophilia. 21, 4, s. 444-450

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hemophilia A 100%
  • Hemorrhage 57%
  • Phenotype 42%
  • Equipment and Supplies 21%
  • Registries 13%

• Mutation analysis of Swedish haemophilia B families - high frequency of unique mutations.

  Mårtensson, A., Letelier, A., Halldén, C. & Ljung, R., 2015, I: Haemophilia.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hemophilia B 100%
  • Mutation Rate 78%
  • Mutation 41%
  • Genetic Counseling 40%
  • Prenatal Diagnosis 37%

• Tailoring care to haemophilia patients' needs: which specialty and when?

  Morfini, M., Benson, G., Jiménez-Yuste, V., Ljung, R., Mannucci, P. M., Pasta, G., Remor, E. & Šalek, S. Z., 2015, I: Blood Transfusion. 13, 4, s. 644-650

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
• 2014

  Clotting factor level is not a good predictor of bleeding in carriers of haemophilia A and B.

  Olsson, A., Hellgren, M., Berntorp, E., Ljung, R. & Baghaei, F., 2014, I: Blood Coagulation and Fibrinolysis. 25, 5, s. 471-475

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hemophilia B 100%
  • Blood Coagulation Factors 84%
  • Hemophilia A 83%
  • Hemorrhage 47%
  • Factor IX 9%

• Definitions in hemophilia: communication from the SSC of the ISTH

  Blanchette, V. S., Key, N. S., Ljung, R., Manco-Johnson, M. J., Van Den Berg, H. M. & Srivastava, A., 2014, I: Journal of Thrombosis and Haemostasis. 12, 11, s. 1935-1939

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

• Prenatal diagnosis of haemophilia in Sweden now more commonly used for psychological preparation than termination of pregnancy.

  Mårtensson, A., Tedgård, U. & Ljung, R., 2014, I: Haemophilia. 20, 6, s. 854-858

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hemophilia A 100%
  • Prenatal Diagnosis 89%
  • Sweden 86%
  • Psychology 60%
  • Pregnancy 53%

• Prospective observational cohort studies for studying rare diseases: the European PedNet Haemophilia Registry

  Fischer, K., Ljung, R., Platokouki, H., Liesner, R., Claeyssens, S., Smink, E. & Van den Berg, H. M., 2014, I: Haemophilia. 20, 4, s. e280-e286

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hemophilia A 100%
  • Rare Diseases 85%
  • Registries 69%
  • Observational Studies 68%
  • Cohort Studies 60%

• Similar bleeding phenotype in young children with haemophilia A or B: A cohort study

  Rodin Study group, 2014 nov. 1, I: Haemophilia. 20, 6, s. 747-755 9 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hemophilia B 100%
  • Hemophilia A 83%
  • Cohort Studies 50%
  • Hemorrhage 47%
  • Phenotype 44%
• 2013

  40K glycoPEGylated, recombinant FVIIa: 3-month, double-blind, randomized trial of safety, pharmacokinetics, and preliminary efficacy in hemophilia patients with inhibitors.

  Ljung, R., Karim, F. A., Saxena, K., Suzuki, T., Arkhammar, P., Rosholm, A. & Giangrande, P., 2013, I: Journal of Thrombosis and Haemostasis. 11, 7, s. 1260-1268

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • recombinant FVIIa 100%
  • Hemophilia A 80%
  • glycoPEGylated factor VIIa 61%
  • Pharmacokinetics 53%
  • Observation 50%