Translationella genomiska och funktionella studier av leukemi

Forskningsoutput

Forskningsoutput per år 2005 2018 2019 2020 2021 2022 2023

• 37 Artikel i vetenskaplig tidskrift
• 8 Doktorsavhandling (sammanläggning)
• 6 Översiktsartikel
• 3 Letter
• 2 Mer
  • 1 Publicerat konferensabstract
  • 1 Debate/Note/Editorial

Forskningsoutput per år

Forskningsoutput per år

Sökresultat

• 2022

  A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development

  Johansson, P. A., Brattås, P. L., Douse, C. H., Hsieh, P., Adami, A., Pontis, J., Grassi, D., Garza, R., Sozzi, E., Cataldo, R., Jönsson, M. E., Atacho, D. A. M., Pircs, K., Eren, F., Sharma, Y., Johansson, J., Fiorenzano, A., Parmar, M., Fex, M., Trono, D., & 2 andraEichler, E. E. & Jakobsson, J., 2022, I: Cell Stem Cell. 29, 1, s. 52-69.e8

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Internal-External Control 100%
  • Gene Regulatory Networks 90%
  • Human Development 89%
  • Pan troglodytes 61%
  • Brain 40%

• A Study Protocol for Validation and Implementation of Whole-Genome and -Transcriptome Sequencing as a Comprehensive Precision Diagnostic Test in Acute Leukemias

  Berglund, E., Barbany, G., Orsmark-Pietras, C., Fogelstrand, L., Abrahamsson, J., Golovleva, I., Hallböök, H., Lazarevic, V., Levin, L. Å., Nordlund, J., Norèn-Nyström, U., Palle, J., Thangavelu, T., Palmqvist, L., Wirta, V., Cavelier, L., Fioretos, T., Rosenquist, R., the Clinical Genomics Platform at SciLifeLab & Genomic Medicine Sweden, 2022, I: Frontiers in Medicine. 9, s. 1-9 842507.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Whole Exome Sequencing 100%
  • Whole Genome Sequencing 97%
  • Validation Studies 93%
  • Routine Diagnostic Tests 79%
  • Leukemia 68%

• High CD34 surface expression in BCP-ALL predicts poor induction therapy response and is associated with altered expression of genes related to cell migration and adhesion

  Modvig, S., Wernersson, R., Øbro, N. F., Olsen, L. R., Christensen, C., Rosthøj, S., Degn, M., Jürgensen, G. W., Madsen, H. O., Albertsen, B. K., Wehner, P. S., Rosthøj, S., Lilljebjörn, H., Fioretos, T., Schmiegelow, K. & Marquart, H. V., 2022, I: Molecular Oncology. 16, 10, s. 2015-2030

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • B-Lymphoid Precursor Cells 100%
  • Residual Neoplasm 88%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 81%
  • Cell Adhesion 77%
  • Cell Movement 68%

• N-terminus DUX4-immunohistochemistry is a reliable methodology for the diagnosis of DUX4-fused B-lymphoblastic leukemia/lymphoma (N-terminus DUX4 IHC for DUX4-fused B-ALL)

  Siegele, B. J., Stemmer-Rachamimov, A. O., Lilljebjorn, H., Fioretos, T., Winters, A. C., Dal Cin, P., Treece, A., Gaskell, A. & Nardi, V., 2022, I: Genes Chromosomes and Cancer. 61, 8, s. 449-458

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Immunohistochemistry 70%
  • RNA-Seq 50%
  • Cytogenetics 28%
  • Staining and Labeling 28%

• The complement receptor C3AR constitutes a novel therapeutic target in NPM1-mutated AML

  von Palffy, S., Thorsson, H., Peña-Martínez, P., Puente-Moncada, N., Sandén, C., Blom, A. M., Henningsson, R., Juliusson, G., King, B., Landberg, N., Lazarevic, V. L., Orsmark-Pietras, C., Rissler, M., Rissler, V., Ågerstam, H., Järås, M., Lilljebjörn, H. & Fioretos, T., 2022 nov. 16, (E-pub ahead of print) I: Blood Advances.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • nucleophosmin 100%
  • Complement Receptors 89%
  • Acute Myeloid Leukemia 64%
  • Myeloid Cells 30%
  • Hematopoietic Stem Cells 22%

• Trailblazing precision medicine in Europe: A joint view by Genomic Medicine Sweden and the Centers for Personalized Medicine, ZPM, in Germany

  GMS working groups and ZPM working groups, 2022, I: Seminars in Cancer Biology. 84, s. 242-254

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Precision Medicine 100%
  • Sweden 90%
  • Germany 82%
  • Medicine 67%
  • Joints 65%

• Transcriptional profiling demonstrates altered characteristics of CD8 + cytotoxic T-cells and regulatory T-cells in TP53-mutated acute myeloid leukemia

  Abolhalaj, M., Sincic, V., Lilljebjörn, H., Sandén, C., Aab, A., Hägerbrand, K., Ellmark, P., Borrebaeck, C., Fioretos, T. & Lundberg, K., 2022, I: Cancer Medicine. 11, 15 , s. 3023-3032

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

• Transcriptomics paving the way for improved diagnostics and precision medicine of acute leukemia

  Lilljebjörn, H., Orsmark-Pietras, C., Mitelman, F., Hagström-Andersson, A. & Fioretos, T., 2022, I: Seminars in Cancer Biology. 84, s. 40-49

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • RNA Sequence Analysis 100%
  • Precision Medicine 96%
  • Leukemia 72%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 58%
  • Acute Myeloid Leukemia 56%
• 2021

  Clinical and genomic characterization of patients diagnosed with the provisional entity Acute myeloid leukemia with BCR-ABL1, a Swedish population-based study

  Orsmark-Pietras, C., Landberg, N., Lorenz, F., Uggla, B., Höglund, M., Lehmann, S., Derolf, Å., Deneberg, S., Antunovic, P., Cammenga, J., Möllgård, L., Wennström, L., Lilljebjörn, H., Rissler, M., Fioretos, T. & Lazarevic, V. L., 2021 juni 1, I: Genes, Chromosomes and Cancer. 60, 6, s. 426-433 8 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Acute Myeloid Leukemia 100%
  • Population 41%
  • Blast Crisis 40%
  • Mutation 33%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 31%

• Combinatorial molecule screening identifies a novel diterpene and the BET inhibitor CPI-203 as differentiation inducers of primary acute myeloid leukemia cells

  Hultmark, S., Baudet, A., Schmiderer, L., Prabhala, P., Palma-Tortosa, S., Sandén, C., Fioretos, T., Sasidharan, R., Larsson, C., Lehmann, S., Juliusson, G., Ek, F. & Magnusson, M., 2021, I: Haematologica. 106, 10

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • cyclopropapyrroloindole 100%
  • Diterpenes 86%
  • Myeloid Cells 65%
  • Acute Myeloid Leukemia 61%
  • Protein Kinase C 36%

• Precisionsmedicin standard vid flera hematologiska sjukdomar

  Hellström Lindberg, E., Cavelier, L., Cammenga, J., Andersson, P. O., Fioretos, T. & Rosenquist, R., 2021 maj, I: Lakartidningen. 118

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hematologic Neoplasms 100%
  • Gain of Function Mutation 43%
  • Whole Exome Sequencing 38%
  • Whole Genome Sequencing 38%
  • Hematology 35%

• Targeting GLUT1 in acute myeloid leukemia to overcome cytarabine resistance

  Åbacka, H., Hansen, J. S., Huang, P., Venskutonytė, R., Hyrenius-Wittsten, A., Poli, G., Tuccinardi, T., Granchi, C., Minutolo, F., Hagström-Andersson, A. K. & Lindkvist-Petersson, K., 2021, I: Haematologica. 106, 4, s. 1163-1166

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång
• 2020

  13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking

  Yang, M., Safavi, S., Woodward, E. L., Duployez, N., Olsson-arvidsson, L., Ungerbäck, J., Sigvardsson, M., Zaliova, M., Zuna, J., Fioretos, T., Johansson, B., Nord, K. H. & Paulsson, K., 2020 aug. 20, I: Blood. 136, 8, s. 946-956 11 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Enhancer 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 82%
  • Tyrosine 76%
  • Protein-Tyrosine Kinases 76%
  • Up-Regulation 60%

• A dynamic mutational landscape associated with an inter-regionally diverse immune response in malignant rhabdoid tumour

  Yasui, H., Valind, A., Karlsson, J., Pietras, C., Jansson, C., Wille, J., Romerius, P., Backman, T. & Gisselsson, D., 2020 sep., I: Journal of Pathology. 252, 1, s. 22-28 7 s., e5490.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Rhabdoid Tumor 100%
  • Neoplasm Metastasis 20%
  • Neoplasms 18%
  • Mutation 18%
  • Tumor-Infiltrating Lymphocytes 10%

• A high-content cytokine screen identifies myostatin propeptide as a positive regulator of primitive chronic myeloid leukemia cells

  von Palffy, S., Landberg, N., Sandén, C., Zacharaki, D., Shah, M., Nakamichi, N., Hansen, N., Askmyr, M., Lilljebjörn, H., Rissler, M., Karlsson, C., Scheding, S., Richter, J., Eaves, C. J., Bhatia, R., Järås, M. & Fioretos, T., 2020, I: Haematologica. 105, 8, s. 2095-2104 10 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Myostatin 100%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 74%
  • Myeloid Cells 71%
  • Cytokines 43%
  • Bone Marrow Cells 9%

• Clonal competition within complex evolutionary hierarchies shapes AML over time

  Sandén, C., Lilljebjörn, H., Orsmark Pietras, C., Henningsson, R., Saba, K. H., Landberg, N., Thorsson, H., von Palffy, S., Peña-Martinez, P., Högberg, C., Rissler, M., Gisselsson, D., Lazarevic, V., Juliusson, G., Ågerstam, H. & Fioretos, T., 2020, I: Nature Communications. 11, 1, 579.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • leukemias 100%
  • hierarchies 68%
  • Acute Myeloid Leukemia 66%
  • Shape 44%
  • Clone Cells 44%

• CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia

  Ramakrishnan, R., Peña-Martínez, P., Agarwal, P., Rodriguez-Zabala, M., Chapellier, M., Högberg, C., Eriksson, M., Yudovich, D., Shah, M., Ehinger, M., Nilsson, B., Larsson, J., Hagström-Andersson, A., Ebert, B. L., Bhatia, R. & Järås, M., 2020 maj 26, I: Cell Reports. 31, 8, 107684.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Acute Myeloid Leukemia 100%
  • Leukemia 57%
  • Oxidative Stress 51%
  • Myeloid Progenitor Cells 47%
  • Myeloid Cells 35%
• 2019

  Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells

  Chapellier, M., Peña-Martínez, P., Ramakrishnan, R., Eriksson, M., Safaee-Talkhoncheh, M., Orsmark-Pietras, C., Lilljebjörn, H., Högberg, C., Hagström-Andersson, A., Fioretos, T., Larsson, J. & Järås, M., 2019, I: Haematologica. 104, 10, s. 2006-2016

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Tumor Necrosis Factor Ligand Superfamily Member 13 100%
  • Acute Myeloid Leukemia 46%
  • Leukemia 39%
  • Myeloid Cells 28%
  • Cytokines 21%

• Disseqt-distribution-based modeling of sequence space time dynamics

  Henningsson, R., Moratorio, G., Bordería, A. V., Vignuzzi, M. & Fontes, M., 2019, I: Virus Evolution. 5, 2, vez028.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Population 100%
  • Genotype 91%
  • Phenotype 57%
  • Biological Evolution 51%
  • Genetic Heterogeneity 37%

• Genetic profiling of a chondroblastoma-like osteosarcoma/malignant phosphaturic mesenchymal tumor of bone reveals a homozygous deletion of CDKN2A, intragenic deletion of DMD, and a targetable FN1-FGFR1 gene fusion

  Saba, K. H., Cornmark, L., Rissler, M., Fioretos, T., Åström, K., Haglund, F., Rosenberg, A. E., Brosjö, O. & Nord, K. H., 2019, I: Genes, Chromosomes and Cancer. 58, 10, s. 731-736

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Chondroblastoma 100%
  • Malignant mesenchymal tumor 97%
  • Gene Fusion 71%
  • Osteosarcoma 66%
  • Bone and Bones 37%

• PAX5 is part of a functional transcription factor network targeted in lymphoid leukemia

  Okuyama, K., Strid, T., Kuruvilla, J., Somasundaram, R., Cristobal, S., Smith, E., Prasad, M., Fioretos, T., Lilljebjörn, H., Soneji, S., Lang, S., Ungerbäck, J. & Sigvardsson, M., 2019 aug. 1, I: PLoS Genetics. 15, 8, e1008280.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Lymphoid Leukemia 100%
  • leukemia 94%
  • transcription factors 56%
  • Transcription Factors 54%
  • mutation 54%

• Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia

  Yang, M., Vesterlund, M., Siavelis, I., Moura-Castro, L. H., Castor, A., Fioretos, T., Jafari, R., Lilljebjörn, H., Odom, D. T., Olsson, L., Ravi, N., Woodward, E. L., Harewood, L., Lehtiö, J. & Paulsson, K., 2019 apr. 3, I: Nature Communications. 10, 1, 1519.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Proteogenomics 100%
  • RNA Sequencing 99%
  • Domain Boundary 88%
  • leukemias 86%
  • Polyploidy 75%

• Recombinant dermatan sulfate is a potent activator of heparin cofactor II-dependent inhibition of thrombin

  Tykesson, E., Maccarana, M., Thorsson, H., Liu, J., Malmström, A., Ellervik, U. & Westergren-Thorsson, G., 2019, I: Glycobiology. 29, 6, s. 446-451

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Heparin Cofactor II 100%
  • Inhibition of Thrombin 95%
  • Dermatan Sulfate 86%
  • Heparin 63%
  • Thrombin 61%
• 2018

  CD36 defines primitive chronic myeloid leukemia cells less responsive to imatinib but vulnerable to antibody-based therapeutic targeting

  Landberg, N., von Palffy, S., Askmyr, M., Lilljebjörn, H., Sandén, C., Rissler, M., Mustjoki, S., Hjorth-Hansen, H., Richter, J., Ågerstam, H., Järås, M. & Fioretos, T., 2018 feb. 28, I: Haematologica. 103, 3, s. 447-455

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Imatinib Mesylate 100%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 92%
  • Myeloid Cells 89%
  • Antibodies 48%
  • Protein-Tyrosine Kinases 40%

• Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6 dependent manner

  Peña, P., Eriksson, M., Ramakrishnan, R., Chapellier, M., Högberg, C., Orsmark-Pietras, C., Richter, J., Andersson, A., Fioretos, T. & Järås, M., 2018, I: Leukemia. 32, 3, s. 588-596

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Myeloid Cells 100%
  • Acute Myeloid Leukemia 93%
  • Interleukin-4 90%
  • Apoptosis 59%
  • Leukemia 13%

• Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases

  Li, J. F., Dai, Y. T., Lilljebjörn, H., Shen, S. H., Cui, B. W., Bai, L., Liu, Y. F., Qian, M. X., Kubota, Y., Kiyoi, H., Matsumura, I., Miyazaki, Y., Olsson, L., Tan, A. M., Ariffin, H., Chen, J., Takita, J., Yasuda, T., Mano, H., Johansson, B., & 8 andraYang, J. J., Yeoh, A. E. J., Hayakawa, F., Chen, Z., Pui, C. H., Fioretos, T., Chen, S. J. & Huang, J. Y., 2018, I: Proceedings of the National Academy of Sciences of the United States of America. 115, 50, s. E11711-E11720

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • B-Lymphoid Precursor Cells 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 81%
  • RNA Sequence Analysis 20%
  • Chromosomes 14%
  • B-Lymphocyte Subsets 11%
• 2017

  Primary cells in BCR/FGFR1-positive 8p11 myeloproliferative syndrome are sensitive to dovitinib, ponatinib, and dasatinib

  Landberg, N., Dreimane, A., Rissler, M., Billström, R. & Ågerstam, H., 2017, I: European Journal of Haematology. 99, 5, s. 442-448 7 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • 4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one 100%
  • ponatinib 90%
  • Receptor, Fibroblast Growth Factor, Type 1 79%
  • Dasatinib 75%
  • Protein-Tyrosine Kinases 37%

• Transgenic expression of human cytokines in immunodeficient mice does not facilitate myeloid expansion of BCR-ABL1 transduced human cord blood cells

  Askmyr, M., Von Palffy, S., Hansen, N., Landberg, N., Högberg, C., Rissler, M., Ågerstam, H. & Fioretos, T., 2017 okt. 1, I: PLoS ONE. 12, 10, e0186035.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Fetal Blood 100%
  • Blood Cells 83%
  • Cytokines 62%
  • Myeloid Cells 38%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 26%
• 2016

  Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia

  Lilljebjörn, H., Henningsson, R., Hyrenius-Wittsten, A., Olsson, L., Orsmark-Pietras, C., Von Palffy, S., Askmyr, M., Rissler, M., Schrappe, M., Cario, G., Castor, A., Pronk, K-J., Behrendtz, M., Mitelman, F., Johansson, B., Paulsson, K., Andersson, A. K., Fontes, M. & Fioretos, T., 2016 juni 6, I: Nature Communications. 7, 11790.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • RNA Sequencing 100%
  • leukemias 87%
  • B-Lymphoid Precursor Cells 72%
  • Gene Fusion 68%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 59%

• IL1RAP antibodies block IL-1-induced expansion of candidate CML stem cells and mediate cell killing in xenograft models

  Ågerstam, H., Hansen, N., von Palffy, S., Sandén, C., Reckzeh, K., Karlsson, C., Lilljebjörn, H., Landberg, N., Askmyr, M., Högberg, C., Rissler, M., Porkka, K., Wadenvik, H., Mustjoki, S., Richter, J., Järås, M. & Fioretos, T., 2016 dec. 8, I: Blood. 128, 23, s. 2683-2693

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Tyrosine Kinase Inhibitor 100%
  • Myeloid Progenitor Cells 96%
  • Effector 78%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 75%
  • Interleukin-1 71%
• 2015

  Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.

  Ågerstam, H., Karlsson, C., Hansen, N., Sandén, C., Askmyr, M., von Palffy, S., Högberg, C., Rissler, M., Wunderlich, M., Juliusson, G., Richter, J., Sjöström, K., Bhatia, R., Mulloy, J. C., Järås, M. & Fioretos, T., 2015, I: Proceedings of the National Academy of Sciences. 112, 34, s. 10786-10791

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Acute Myeloid Leukemia 100%
  • Heterografts 94%
  • Therapeutic Uses 86%
  • Antibodies 58%
  • Interleukin-1 44%
  297 Nedladdningar (Pure)

• IL1RAP expression as a measure of leukemic stem cell burden at diagnosis of chronic myeloid leukemia predicts therapy outcome.

  Landberg, N., Hansen, N., Askmyr, M., Ågerstam, H., Lassen, C., Rissler, M., Hansen, H. H., Mustjoki, S., Järås, M., Richter, J. & Fioretos, T., 2015, I: Leukemia. 30, 1, s. 255-258

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil
  619 Nedladdningar (Pure)

• The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.

  Paulsson, K., Lilljebjörn, H., Biloglav, A., Olsson, L., Rissler, M., Castor, A., Barbany, G., Fogelstrand, L., Nordgren, A., Sjögren, H., Fioretos, T. & Johansson, B., 2015, I: Nature Genetics. 47, 6, s. 672-676

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Polyploidy 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 77%
  • Tetrasomy 43%
  • Chromosomes 41%
  • Pediatrics 34%
  446 Nedladdningar (Pure)
• 2013

  Selective killing of candidate AML stem cells by antibody targeting of IL1RAP.

  Askmyr, M., Ågerstam, H., Hansen, N., Gordon, S., Arvanitakis, A., Rissler, M., Juliusson, G., Richter, J., Järås, M. & Fioretos, T., 2013, I: Blood. 121, 18, s. 3709-3713

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Stem Cells 100%
  • Antibodies 75%
  • Therapeutics 22%
• 2010

  Isolation and killing of candidate chronic myeloid leukemia stem cells by antibody targeting of IL-1 receptor accessory protein.

  Järås, M., Johnels, P., Hansen, N., Ågerstam, H., Tsapogas, P., Rissler, M., Lassen, C., Olofsson, T., Bjerrum, O. W., Richter, J. & Fioretos, T., 2010, I: Proceedings of the National Academy of Sciences. 107, 37, s. 16280-16285

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Myeloid Progenitor Cells 100%
  • Interleukin-1 Receptors 87%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 77%
  • Antibodies 40%
  • Proteins 27%

• Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice

  Ågerstam, H., Järås, M., Andersson, A., Johnels, P., Hansen, N., Lassen, C., Rissler, M., Gisselsson Nord, D., Olofsson, T., Richter, J., Fan, X., Ehinger, M. & Fioretos, T., 2010, I: Blood. 116, 12, s. 2103-2111

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Disorder 100%
  • Myeloproliferative Disorders 76%
  • Leukemia 71%
  • Oncogene Fusion 48%
  • Receptor, Fibroblast Growth Factor, Type 1 42%
• 2005

  Molecular signatures in childhood acute leukemia and their correlations to expression patterns in normal hematopoietic subpopulations.

  Andersson, A., Olofsson, T., Lindgren, D., Nilsson, B., Ritz, C., Edén, P., Lassen, C., Råde, J., Fontes, M., Mörse, H., Heldrup, J., Behrendtz, M., Mitelman, F., Höglund, M., Johansson, B. & Fioretos, T., 2005, I: Proceedings of the National Academy of Sciences. 102, 52, s. 19069-19074

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

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