Charlotta Böiers

Sökresultat

• 2023

  Single-cell multiomics of human fetal hematopoiesis define a developmental-specific population and a fetal signature

  Sommarin, M. N. E., Olofzon, R., Palo, S., Dhapola, P., Soneji, S., Karlsson, G. & Böiers, C., 2023 sep., I: Blood Advances. 7, 18, s. 5325-5340 16 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Cells 100%
  • Blood 100%
  • Adult 80%
  • Gene 66%
  • Hematopoietic Stem Cell 66%

• In vitro clonal multilineage differentiation of distinct murine hematopoietic progenitor populations

  Safi, F., Dhapola, P., Erlandsson, E., Ulfsson, L. G., Calderón, A. S., Böiers, C. & Karlsson, G., 2023 mars 17, I: STAR Protocols. 4, 1, 101965.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Experiment 100%
  • Hematopoietic Stem Cell 100%
• 2022

  Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability

  Wray, J. P., Deltcheva, E. M., Boiers, C., Richardson, S., Chhetri, J. B., Brown, J., Gagrica, S., Guo, Y., Illendula, A., Martens, J. H. A., Stunnenberg, H. G., Bushweller, J. H., Nimmo, R. & Enver, T., 2022 dec., I: Nature Communications. 13, 1, 7124.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • RUNX1 100%
  • ETV6 41%
  • Genetics 8%
  • Binding Site 8%
  • Hematopoiesis 8%

• Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction

  Safi, F., Dhapola, P., Warsi, S., Sommarin, M., Erlandsson, E., Ungerbäck, J., Warfvinge, R., Sitnicka, E., Bryder, D., Böiers, C., Thakur, R. K. & Karlsson, G., 2022 maj 10, I: Cell Reports. 39, 6, 110798.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Chromatin 100%
  • Hematopoietic Stem Cell 100%
  • Lineages 100%
  • Differentiation 28%
  • Myeloid 25%
• 2021

  In vitro differentiation of human pluripotent stem cells into the B lineage using OP9-MS5 co-culture

  Richardson, S. E., Ghazanfari, R., Chhetri, J., Enver, T. & Böiers, C., 2021, I: STAR Protocols. 2, 2, 100420.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Surface Property 100%
  • Target Cell 100%

• TLR7 ligation augments hematopoiesis in Rps14 (uS11) deficiency via paradoxical suppression of inflammatory signalling

  Peña, O. A., Lubin, A., Hockings, C., Rowell, J., Jung, Y., Hoade, Y., Dace, P., Valdivia, L. E., Tuschl, K., Böiers, C., Virgilio, M. C., Richardson, S. & Payne, E., 2021, I: Blood Advances. 5, 20, s. 4112–4124

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Myelodysplastic Syndrome 100%
  • Toll Like Receptor 7 100%
  • Ligation 100%
  • Anemia 50%
  • Patient 16%
• 2020

  Generation and trapping of a mesoderm biased state of human pluripotency

  Stavish, D., Böiers, C., Price, C., Frith, T. J. R., Halliwell, J., Saldaña-Guerrero, I., Wray, J., Brown, J., Carr, J., James, C., Barbaric, I., Andrews, P. W. & Enver, T., 2020 dec. 1, I: Nature Communications. 11, 4989.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Mesoderm 100%
  • Plasticity 33%
  • Stem Cell Culture 33%
• 2019

  Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform

  Stacey, G. N., Andrews, P. W., Barbaric, I., Boiers, C., Chandra, A., Cossu, G., Csontos, L., Frith, T. J., Halliwell, J. A., Hewitt, Z., McCall, M., Moore, H. D., Parmar, M., Panico, M. B., Pisupati, V., Shichkin, V. P., Stacey, A. R., Tedesco, F. S., Thompson, O. & Wagey, R., 2019, I: Regenerative Medicine. 14, 3, s. 243-255

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

  Öppen tillgång

  • Stem Cell 100%
  • Pluripotent Stem Cell 100%
  • Stem Cell Culture 100%
  • Joints (Structural Components) 100%
  • Culture Condition 100%
• 2018

  LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis

  Peltzer, N., Darding, M., Montinaro, A., Draber, P., Draberova, H., Kupka, S., Rieser, E., Fisher, A., Hutchinson, C., Taraborrelli, L., Hartwig, T., Lafont, E., Haas, T. L., Shimizu, Y., Böiers, C., Sarr, A., Rickard, J., Alvarez-Diaz, S., Ashworth, M. T., Beal, A., & 7 andraEnver, T., Bertin, J., Kaiser, W., Strasser, A., Silke, J., Bouillet, P. & Walczak, H., 2018 maj 3, I: Nature. 557, 7703, s. 112-117 6 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hematopoiesis 100%
  • Embryogenesis 100%
  • Ubiquitin 100%
  • Mouse 57%
  • Caspase 42%

• A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1

  Böiers, C., Richardson, S. E., Laycock, E., Zriwil, A., Turati, V. A., Brown, J., Wray, J. P., Wang, D., James, C., Herrero, J., Sitnicka, E., Karlsson, S., Smith, A. J. H., Jacobsen, S. E. W. & Enver, T., 2018 feb. 5, I: Developmental Cell. 44, 3, s. 362-377.e7

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Childhood 100%
  • Acute Lymphoblastic Leukemia 100%
  • Myeloid 100%
  • ETV6 100%
  • RUNX1 100%

• Direct role of FLT3 in regulation of early lymphoid progenitors

  Zriwil, A., Böiers, C., Kristiansen, T. A., Wittmann, L., Yuan, J., Nerlov, C., Sitnicka, E. & Jacobsen, S. E. W., 2018, I: British Journal of Haematology. 183, 4, s. 588-600 13 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Adult 100%
  • B Cell 100%
  • Lymphopoiesis 100%
  • Prognosis 50%
  • Fetus 50%
• 2017

  Don't judge a cell by its cover: heterogeneity within early lymphoid progenitors

  Karlsson, G., Sigvardsson, M. & Böiers, C., 2017 dec. 15, I: EMBO Journal. 36, 24, s. 3552-3554 3 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

• Single-Cell Analysis Identifies Distinct Stages of Human Endothelial-to-Hematopoietic Transition

  Guibentif, C., Rönn, R. E., Böiers, C., Lang, S., Saxena, S., Soneji, S., Enver, T., Karlsson, G. & Woods, N-B., 2017 apr. 4, I: Cell Reports. 19, 1, s. 10-19 10 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Single-Cell Analysis 100%
  • Hematopoietic Cell 100%
  • Single Cell Analysis 100%
  • Gene 50%
  • Hematopoietic Stem Cell 50%
• 2016

  Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors

  Luis, T. C., Luc, S., Mizukami, T., Boukarabila, H., Thongjuea, S., Woll, P. S., Azzoni, E., Giustacchini, A., Lutteropp, M., Bouriez-Jones, T., Vaidya, H., Mead, A. J., Atkinson, D., Böiers, C., Carrelha, J., MacAulay, I. C., Patient, R., Geissmann, F., Nerlov, C., Sandberg, R., & 4 andraDe Bruijn, M. F. T. R., Blackburn, C. C., Godin, I. & Jacobsen, S. E. W., 2016 dec. 1, I: Nature Immunology. 17, 12, s. 1424-1435 12 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Thymus 100%
  • T Cell 50%
  • Cell Lineage 33%
  • Lineages 16%
  • Identity 16%

• Macrophage colony-stimulating factor receptor marks and regulates a fetal myeloid-primed B-cell progenitor in mice

  Zriwil, A., Böiers, C., Wittmann, L., Green, J. C. A., Woll, P. S., Jacobsen, S. E. W. & Sitnicka, E., 2016, I: Blood. 128, 2, s. 217-226 10 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Mouse 100%
  • B Cell 100%
  • Colony Stimulating Factor 1 Receptor 100%
  • Macrophage Colony-Stimulating Factor 100%
  • Colony Stimulating Factor 1 100%
• 2013

  Lymphomyeloid Contribution of an Immune-Restricted Progenitor Emerging Prior to Definitive Hematopoietic Stem Cells.

  Böiers, C., Carrelha, J., Lutteropp, M., Luc, S., Green, J. C. A., Azzoni, E., Woll, P. S., Mead, A. J., Hultquist, A., Swiers, G., Perdiguero, E. G., Macaulay, I. C., Melchiori, L., Luis, T. C., Kharazi, S., Bouriez-Jones, T., Deng, Q., Pontén, A., Atkinson, D., Jensen, C., & 6 andraSitnicka Quinn, E., Geissmann, F., Godin, I., Sandberg, R., de Bruijn, M. F. T. R. & Jacobsen, S. E. W., 2013, I: Cell Stem Cell. 13, 5, s. 535-548

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Yolk Sac 100%
• 2011

  Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation

  Kharazi, S., Mead, A. J., Mansour, A., Hultquist, A., Böiers, C., Luc, S., Buza-Vidas, N., Ma, Z., Ferry, H., Atkinson, D., Reckzeh, K., Masson, K., Cammenga, J., Rönnstrand, L., Arai, F., Suda, T., Nerlov, C., Sitnicka Quinn, E. & Jacobsen, S. E. W., 2011, I: Blood. 118, 13, s. 3613-3621

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Allele 100%
  • Myeloid 100%
  • Ligand 100%
  • Myeloproliferative Disorder 100%
  • Phenotype 50%
• 2010

  Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development.

  Böiers, C., Buza-Vidas, N., Jensen, C., Pronk, K-J., Kharazi, S., Wittmann, L., Sitnicka Quinn, E., Hultquist, A. & Jacobsen, S. E. W., 2010, I: Blood. May 4, s. 5061-5068

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Regulatory Mechanism 100%
  • Monocyte 100%
  • Granulocyte 100%
  • Myeloid 57%
  • Ligand 42%
• 2008

  Downregulation of Mpl marks the transition to lymphoid-primed multipotent progenitors with gradual loss of granulocyte-monocyte potential.

  Luc, S., Anderson, K., Kharazi, S., Buza-Vidas, N., Böiers, C., Jensen, C., Ma, Z., Wittmann, L. & Jacobsen, S. E. W., 2008, I: Blood. 111, 7, s. 3424-3434

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Monocyte 100%
  • Granulocyte 100%
  • Lineages 71%
  • Mouse 14%
  • Cell Lineage 14%

• FLT3 ligand and not TSLP is the key regulator of IL-7-independent B-1 and B-2 B Lymphopoiesis.

  Jensen, C., Kharazi, S., Böiers, C., Cheng, M., Lübking, A., Sitnicka Quinn, E. & Jacobsen, S. E. W., 2008, I: Blood. 112, s. 2297-2304

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Ligand 100%
  • Lymphopoiesis 100%
  • Interleukin 7 100%
  • B Cell 45%
  • Adult 36%

• Permissive roles of hematopoietin and cytokine tyrosine kinase receptors in early T cell development

  Jensen, C., Böiers, C., Kharazi, S., Lübking, A., Rydén, T., Sigvardsson, M., Sitnicka Quinn, E. & Jacobsen, S. E. W., 2008, I: Blood. 111, 4, s. 2083-2090

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • T Cell Development 100%
  • Interleukin 7 100%
  • Lymphopoiesis 80%
  • Mouse 60%
  • T Cell 20%
• 2000

  Effect of high-fat diet, surrounding temperature, and enterostatin on uncoupling protein gene expression

  Rippe, C., Berger, K., Böiers, C., Ricquier, D. & Erlanson-Albertsson, C., 2000, I: American Journal of Physiology: Endocrinology and Metabolism. 279, 2, s. E293-E300

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Gene Expression 100%
  • Temperature 100%
  • High Fat Diet 100%
  • Uncoupling Protein 100%
  • Fat Intake 71%