Charlotta Böiers

Sökresultat

• 2023

  In vitro clonal multilineage differentiation of distinct murine hematopoietic progenitor populations

  Safi, F., Dhapola, P., Erlandsson, E., Ulfsson, L. G., Calderón, A. S., Böiers, C. & Karlsson, G., 2023 mars 17, I: STAR Protocols. 4, 1, 101965.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Genomics 100%
  • Coculture Techniques 98%
  • Hematopoietic Stem Cells 97%
  • Cell Culture Techniques 75%
  • Cell Count 74%
• 2022

  Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction

  Safi, F., Dhapola, P., Warsi, S., Sommarin, M., Erlandsson, E., Ungerbäck, J., Warfvinge, R., Sitnicka, E., Bryder, D., Böiers, C., Thakur, R. K. & Karlsson, G., 2022 maj 10, I: Cell Reports. 39, 6, 110798.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Hematopoietic Stem Cells 100%
  • Heterogeneity 93%
  • Tyrosine 92%
  • Chromatin 89%
  • Application 31%

• Regulome analysis in B-acute lymphoblastic leukemia exposes Core Binding Factor addiction as a therapeutic vulnerability

  Wray, J. P., Deltcheva, E. M., Boiers, C., Richardson, S., Chhetri, J. B., Brown, J., Gagrica, S., Guo, Y., Illendula, A., Martens, J. H. A., Stunnenberg, H. G., Bushweller, J. H., Nimmo, R. & Enver, T., 2022 dec., I: Nature Communications. 13, 1, 7124.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • RNA Sequencing 100%
  • Core Binding Factors 94%
  • leukemias 87%
  • vulnerability 83%
  • Cell Death 64%
• 2021

  In vitro differentiation of human pluripotent stem cells into the B lineage using OP9-MS5 co-culture

  Richardson, S. E., Ghazanfari, R., Chhetri, J., Enver, T. & Böiers, C., 2021, I: STAR Protocols. 2, 2, 100420.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Pluripotent Stem Cells 100%
  • Coculture Techniques 85%
  • Marker 74%
  • Human Development 46%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 41%

• TLR7 ligation augments hematopoiesis in Rps14 (uS11) deficiency via paradoxical suppression of inflammatory signalling

  Peña, O. A., Lubin, A., Hockings, C., Rowell, J., Jung, Y., Hoade, Y., Dace, P., Valdivia, L. E., Tuschl, K., Böiers, C., Virgilio, M. C., Richardson, S. & Payne, E., 2021, I: Blood Advances. 5, 20, s. 4112–4124

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Myelodysplastic Syndromes 100%
  • Hematopoiesis 96%
  • Ligation 77%
  • Imiquimod 60%
  • Chromosome 5q Deletion Syndrome 49%
• 2020

  Generation and trapping of a mesoderm biased state of human pluripotency

  Stavish, D., Böiers, C., Price, C., Frith, T. J. R., Halliwell, J., Saldaña-Guerrero, I., Wray, J., Brown, J., Carr, J., James, C., Barbaric, I., Andrews, P. W. & Enver, T., 2020 dec. 1, I: Nature Communications. 11, 4989.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Lysophosphatidic Acid 100%
  • Plastic Property 75%
  • stem cells 71%
  • Mesoderm 70%
  • trapping 49%
• 2019

  Stem cell culture conditions and stability: a joint workshop of the PluriMes Consortium and Pluripotent Stem Cell Platform

  Stacey, G. N., Andrews, P. W., Barbaric, I., Boiers, C., Chandra, A., Cossu, G., Csontos, L., Frith, T. J., Halliwell, J. A., Hewitt, Z., McCall, M., Moore, H. D., Parmar, M., Panico, M. B., Pisupati, V., Shichkin, V. P., Stacey, A. R., Tedesco, F. S., Thompson, O. & Wagey, R., 2019, I: Regenerative Medicine. 14, 3, s. 243-255

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

  Öppen tillgång

  • Stem cells 100%
  • Cell culture 91%
  • Pluripotent Stem Cells 82%
  • Cell Culture Techniques 54%
  • Stem Cells 52%
• 2018

  A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1

  Böiers, C., Richardson, S. E., Laycock, E., Zriwil, A., Turati, V. A., Brown, J., Wray, J. P., Wang, D., James, C., Herrero, J., Sitnicka, E., Karlsson, S., Smith, A. J. H., Jacobsen, S. E. W. & Enver, T., 2018 feb. 5, I: Developmental Cell. 44, 3, s. 362-377.e7

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Developmental 100%
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 81%
  • Pluripotent Stem Cells 72%
  • Oncogenes 39%
  • Mutation 34%

• Direct role of FLT3 in regulation of early lymphoid progenitors

  Zriwil, A., Böiers, C., Kristiansen, T. A., Wittmann, L., Yuan, J., Nerlov, C., Sitnicka, E. & Jacobsen, S. E. W., 2018, I: British Journal of Haematology. 183, 4, s. 588-600 13 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Lymphoid Progenitor Cells 100%
  • Lymphopoiesis 91%
  • B-Cell Leukemia 44%
  • B-Lymphoid Precursor Cells 38%
  • Leukemia 25%

• LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis

  Peltzer, N., Darding, M., Montinaro, A., Draber, P., Draberova, H., Kupka, S., Rieser, E., Fisher, A., Hutchinson, C., Taraborrelli, L., Hartwig, T., Lafont, E., Haas, T. L., Shimizu, Y., Böiers, C., Sarr, A., Rickard, J., Alvarez-Diaz, S., Ashworth, M. T., Beal, A., & 7 andraEnver, T., Bertin, J., Kaiser, W., Strasser, A., Silke, J., Bouillet, P. & Walczak, H., 2018 maj 3, I: Nature. 557, 7703, s. 112-117 6 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hematopoiesis 100%
  • Ubiquitin 92%
  • Embryonic Development 84%
  • Cell Death 69%
  • Receptors, Tumor Necrosis Factor, Type I 64%
• 2017

  Don't judge a cell by its cover: heterogeneity within early lymphoid progenitors

  Karlsson, G., Sigvardsson, M. & Böiers, C., 2017 dec. 15, I: EMBO Journal. 36, 24, s. 3552-3554 3 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift

• Single-Cell Analysis Identifies Distinct Stages of Human Endothelial-to-Hematopoietic Transition

  Guibentif, C., Rönn, R. E., Böiers, C., Lang, S., Saxena, S., Soneji, S., Enver, T., Karlsson, G. & Woods, N-B., 2017 apr. 4, I: Cell Reports. 19, 1, s. 10-19 10 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Single-Cell Analysis 100%
  • Developmental 90%
  • Cytometry 77%
  • Flow 47%
  • Pluripotent Stem Cells 14%
• 2016

  Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors

  Luis, T. C., Luc, S., Mizukami, T., Boukarabila, H., Thongjuea, S., Woll, P. S., Azzoni, E., Giustacchini, A., Lutteropp, M., Bouriez-Jones, T., Vaidya, H., Mead, A. J., Atkinson, D., Böiers, C., Carrelha, J., MacAulay, I. C., Patient, R., Geissmann, F., Nerlov, C., Sandberg, R., & 4 andraDe Bruijn, M. F. T. R., Blackburn, C. C., Godin, I. & Jacobsen, S. E. W., 2016 dec. 1, I: Nature Immunology. 17, 12, s. 1424-1435 12 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Thymus Gland 100%
  • Cell Lineage 43%
  • T-Lymphocytes 38%
  • Multipotent Stem Cells 28%
  • Embryonic Structures 17%

• Macrophage colony-stimulating factor receptor marks and regulates a fetal myeloid-primed B-cell progenitor in mice

  Zriwil, A., Böiers, C., Wittmann, L., Green, J. C. A., Woll, P. S., Jacobsen, S. E. W. & Sitnicka, E., 2016, I: Blood. 128, 2, s. 217-226 10 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Colony-Stimulating Factor Receptors 100%
  • Macrophage Colony-Stimulating Factor Receptors 99%
  • Colony Stimulating Factor 97%
  • Macrophage Colony-Stimulating Factor 79%
  • B-Lymphoid Precursor Cells 78%
• 2013

  Lymphomyeloid Contribution of an Immune-Restricted Progenitor Emerging Prior to Definitive Hematopoietic Stem Cells.

  Böiers, C., Carrelha, J., Lutteropp, M., Luc, S., Green, J. C. A., Azzoni, E., Woll, P. S., Mead, A. J., Hultquist, A., Swiers, G., Perdiguero, E. G., Macaulay, I. C., Melchiori, L., Luis, T. C., Kharazi, S., Bouriez-Jones, T., Deng, Q., Pontén, A., Atkinson, D., Jensen, C., & 6 andraSitnicka Quinn, E., Geissmann, F., Godin, I., Sandberg, R., de Bruijn, M. F. T. R. & Jacobsen, S. E. W., 2013, I: Cell Stem Cell. 13, 5, s. 535-548

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Hematopoietic Stem Cells 100%
  • Immune System 80%
  • Lymphopoiesis 48%
  • Yolk Sac 44%
  • Hematopoiesis 36%
• 2011

  Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation

  Kharazi, S., Mead, A. J., Mansour, A., Hultquist, A., Böiers, C., Luc, S., Buza-Vidas, N., Ma, Z., Ferry, H., Atkinson, D., Reckzeh, K., Masson, K., Cammenga, J., Rönnstrand, L., Arai, F., Suda, T., Nerlov, C., Sitnicka Quinn, E. & Jacobsen, S. E. W., 2011, I: Blood. 118, 13, s. 3613-3621

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • flt3 ligand protein 100%
  • Gene Dosage 79%
  • Growth Factor 78%
  • Mutation 56%
  • Alleles 48%
• 2010

  Expression and role of FLT3 in regulation of the earliest stage of normal granulocyte-monocyte progenitor development.

  Böiers, C., Buza-Vidas, N., Jensen, C., Pronk, K-J., Kharazi, S., Wittmann, L., Sitnicka Quinn, E., Hultquist, A. & Jacobsen, S. E. W., 2010, I: Blood. May 4, s. 5061-5068

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Granulocyte Precursor Cells 100%
  • Monocytes 63%
  • Mutation 43%
  • Thrombopoietin 34%
  • Ligand 33%
• 2008

  Downregulation of Mpl marks the transition to lymphoid-primed multipotent progenitors with gradual loss of granulocyte-monocyte potential.

  Luc, S., Anderson, K., Kharazi, S., Buza-Vidas, N., Böiers, C., Jensen, C., Ma, Z., Wittmann, L. & Jacobsen, S. E. W., 2008, I: Blood. 111, 7, s. 3424-3434

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Megakaryocytes 100%
  • Granulocytes 82%
  • Monocytes 68%
  • Down-Regulation 58%
  • Thrombopoietin Receptors 21%

• FLT3 ligand and not TSLP is the key regulator of IL-7-independent B-1 and B-2 B Lymphopoiesis.

  Jensen, C., Kharazi, S., Böiers, C., Cheng, M., Lübking, A., Sitnicka Quinn, E. & Jacobsen, S. E. W., 2008, I: Blood. 112, s. 2297-2304

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • thymic stromal lymphopoietin 100%
  • Lymphopoiesis 96%
  • Interleukin-7 86%
  • Developmental 81%
  • Ligands 47%

• Permissive roles of hematopoietin and cytokine tyrosine kinase receptors in early T cell development

  Jensen, C., Böiers, C., Kharazi, S., Lübking, A., Rydén, T., Sigvardsson, M., Sitnicka Quinn, E. & Jacobsen, S. E. W., 2008, I: Blood. 111, 4, s. 2083-2090

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Hematopoietic Cell Growth Factors 100%
  • Lymphopoiesis 83%
  • Receptor Protein-Tyrosine Kinases 62%
  • Interleukin-7 56%
  • Tyrosine 53%
• 2000

  Effect of high-fat diet, surrounding temperature, and enterostatin on uncoupling protein gene expression

  Rippe, C., Berger, K., Böiers, C., Ricquier, D. & Erlanson-Albertsson, C., 2000, I: American Journal of Physiology: Endocrinology and Metabolism. 279, 2, s. E293-E300

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • procolipase 100%
  • Mitochondrial Uncoupling Proteins 80%
  • Uncoupling Protein 1 77%
  • Brown Adipose Tissue 66%
  • High Fat Diet 54%