Personlig profil

Forskning

My main research interest is molecular biology, and especially microbiology and bacterial genetics.

I did my bachelor's studies in pharmaceutical sciences. Learning about cellular and molecular biology during my undergraduate studies has made me develop an appreciation for the fascinating molecular machines controlling the biological world. Molecular processes have evolved across the earliest life forms, the bacteria, to their present-day multicellular decedents by evolution and diversification. The chemistry of every individual organism is complex, yet at its core, is conserved. I have always loved how microbiology has helped humans answer questions about themselves, because to understand complex organisms, one can begin by understanding bacteria, the relatively simpler, yet specialised and sophisticated ancestors. Indeed, we now know that bacteria are not just bags of enzymes as first thought, but elegant molecular machines, functioning with complex spatial molecular organisation. It’s always been thrilling for me to learn about the molecular basis of the different processes that occur in microbes, and how small molecules inside the cells can control cell differentiation and division as well as other complex cellular functions and developmental processes. Also, with their quick generation time, bacteria evolve at a massive rate, allowing them to live in most places available on the planet, sometimes even at the expense of humans and animals.

If we want to understand how bacteria function, we should understand how they interact with the world. For example, antibiotics that vanquish bacterial diseases are in fact products of microbial warfare. We also learned quickly that antibiotics, after being seen as Panacea for diseases, have quickly turned into a problem when microbes evolved to resist them. Living in a world where antibiotic-resistant bacterial infections continue to be a major cause for a significant number of deaths worldwide, scientists are on the frontline to help in alleviating this issue, and studying bacterial cell biology is crucial to find new antibiotic targets to help mitigate this problem.

For all these reasons, I made the decision to major in this field and chose to do a master’s program in molecular biology with a specialization in microbiology at Lund University. During my master’s studies, I have gained extensive practical experience in cellular and molecular biology techniques. My master's degree project was about investigating the roles of two proteins, SepF2 and SepF3, that are involed in cell division in the very unique model organism, Streptomyces venezuelae. Streptomycetes, those bacterial superheroes who save hundreds of thousands of lives each year by the antibiotics they produce, are unique in their growth and cell division. Having a background in pharmaceutical sciences, streptomycetes which have benefited the pharmaceutical industry for years due to their ability to produce lots of valuable compounds, were also of great interest to me.

Now that I started my PhD, I am looking forward to building upon my knowledge of the molecular mechanisms involved in cell biology and to leverage my experience in research and laboratory work.

 

Ämnesklassifikation (UKÄ)

  • Mikrobiologi
  • Biokemi och molekylärbiologi
  • Cellbiologi
  • Genetik

Fingeravtryck

Utforska forskningsämnen där Dima Massri är aktiv. Dessa ämnesetiketter kommer från personens arbeten. Tillsammans bildar de ett unikt fingeravtryck.
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