Erik Renström

Sökresultat

• 2023

  Reduced volume of diabetic pancreatic islets in rodents detected by synchrotron X-ray phase-contrast microtomography and deep learning network

  Guo, Q., AlKendi, A., Jiang, X., Mittone, A., Wang, L., Larsson, E., Bravin, A., Renström, E., Fang, X. & Zhang, E., 2023 feb., I: Heliyon. 9, 2, e13081.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • islets of Langerhans 100%
  • learning 75%
  • X-radiation 72%
  • rodents 69%
  • pancreas 41%
• 2022

  A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic β-cells

  Ye, Y., Barghouth, M., Dou, H., Luan, C., Wang, Y., Karagiannopoulos, A., Jiang, X., Krus, U., Fex, M., Zhang, Q., Eliasson, L., Rorsman, P., Zhang, E. & Renström, E., 2022 dec., I: Nature Communications. 13, 1, 4237.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • insulin 100%
  • secretions 96%
  • glucose 80%
  • Insulin Derivative 71%
  • Insulin Secretion 69%

• Alternative splicing encodes functional intracellular CD59 isoforms that mediate insulin secretion and are down-regulated in diabetic islets

  Golec, E., Ekström, A., Noga, M., Omar-Hmeadi, M., Lund, P-E., Villoutreix, B. O., Krus, U., Wozniak, K., Korsgren, O., Renström, E., Barg, S., King, B. C. & Blom, A. M., 2022, I: Proceedings of the National Academy of Sciences of the United States of America. 119, 24, 10 s., e2120083119.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Alternative Splicing 100%
  • Insulin Secretion 91%
  • Protein Isoforms 74%
  • Therapeutics 5%

• Debatt: Sverige måsta satsa på utvecklning av nya halvledare

  Renström, E. & Linke, H., 2022 feb. 16, Dagens Industri.

  Forskningsoutput: Bidrag till övrig tidskrift/dags- eller nyhetstidning › Dagstidnings-/nyhetsartikel

• Islet Gene View-a tool to facilitate islet research

  Asplund, O., Storm, P., Chandra, V., Hatem, G., Ottosson-Laakso, E., Mansour-Aly, D., Krus, U., Ibrahim, H., Ahlqvist, E., Tuomi, T., Renström, E., Korsgren, O., Wierup, N., Ibberson, M., Solimena, M., Marchetti, P., Wollheim, C., Artner, I., Mulder, H., Hansson, O., & 3 andraOtonkoski, T., Groop, L. & Prasad, R. B., 2022, I: Life Science Alliance. 5, 12, e202201376.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Insulin Derivative 100%
  • gene 74%
  • diabetes 56%
  • RNA Sequencing 54%
  • Amylin 51%

• MAFA and MAFB regulate exocytosis-related genes in human β-cells

  Cataldo, R., Singh, T., Achanta, K., Bsharat, S., Prasad, R. B., Luan, C., Renström, E., Eliasson, L. & Artner, I., 2022, I: Acta Physiologica. 234, 2, e13761.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Exocytosis 100%
  • Type 2 Diabetes Mellitus 37%
  • Genes 36%
  • Insulin 20%
  • Insulin Secretion 19%

• The Calcium Channel Subunit Gamma-4 as a Novel Regulator of MafA in Pancreatic Beta-Cell Controls Glucose Homeostasis

  Wu, R., Karagiannopoulos, A., Eliasson, L., Renström, E., Luan, C. & Zhang, E., 2022, I: Biomedicines. 10, 4, 770.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Calcium Channels 100%
  • Insulin-Secreting Cells 99%
  • Insulin Derivative 75%
  • Glucose 68%
  • Homeostasis 68%

• The structure of insulin granule core determines secretory capacity being reduced in type-2 diabetes

  Barghouth, M., Jiang, X., Nagao, M., Chen, N., Yang, D., Ye, Y., Luan, C., Gomez, M. F., Blom, A. M., Wollheim, C. B., Eliasson, L., Renström, E. & Zhang, E., 2022 feb. 23, bioRxiv.

  Forskningsoutput: Working paper/Preprint › Preprint (i preprint-arkiv)

  • Type 2 Diabetes Mellitus 100%
  • Insulin 90%
  • Exocytosis 42%
  • Insulin Secretion 37%
  • Nucleobindins 34%

• The T-type calcium channel CaV3.2 regulates insulin secretion in the pancreatic β-cell

  Barghouth, M., Ye, Y., Karagiannopoulos, A., Ma, Y., Cowan, E., Wu, R., Eliasson, L., Renström, E., Luan, C. & Zhang, E., 2022 okt. 31, I: Cell Calcium. 108, 102669.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • T-Type Calcium Channels 100%
  • Insulin Secretion 65%
  • Membrane Potentials 32%
  • Insulin 22%
  • Glucose 20%
• 2021

  Elevated circulating follistatin associates with an increased risk of type 2 diabetes

  Wu, C., Borné, Y., Gao, R., López Rodriguez, M., Roell, W. C., Wilson, J. M., Regmi, A., Luan, C., Aly, D. M., Peter, A., Machann, J., Staiger, H., Fritsche, A., Birkenfeld, A. L., Tao, R., Wagner, R., Canouil, M., Hong, M-G., Schwenk, J. M., Ahlqvist, E., & 22 andraKaikkonen, M. U., Nilsson, P., Shore, A. C., Khan, F., Natali, A., Melander, O., Orho-Melander, M., Nilsson, J., Häring, H-U., Renström, E., Wollheim, C. B., Engström, G., Weng, J., Pearson, E. R., Franks, P. W., White, M. F., Duffin, K. L., Vaag, A. A., Laakso, M., Stefan, N., Groop, L. & De Marinis, Y., 2021, I: Nature Communications. 12, s. 1-10 6486.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Follistatin 100%
  • Sweden 91%
  • genes 80%
  • adipose tissues 68%
  • insulin 66%

• Epigenome-Wide Histone Acetylation Changes in Peripheral Blood Mononuclear Cells in Patients with Type 2 Diabetes and Atherosclerotic Disease

  Bompada, P., Goncalves, I., Wu, C., Gao, R., Sun, J., Mir, B. A., Luan, C., Renström, E., Groop, L., Weng, J., Hansson, O., Edsfeldt, A. & De Marinis, Y., 2021 dec. 14, I: Biomedicines. 9, 12, 1908.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Glycemic 100%
  • Epigenome 79%
  • Histone 68%
  • Acetylation 67%
  • Lysine 60%

• The MafA-target gene PPP1R1A regulates GLP1R-mediated amplification of glucose-stimulated insulin secretion in β-cells

  Cataldo, L. R., Vishnu, N., Singh, T., Bertonnier-Brouty, L., Bsharat, S., Luan, C., Renström, E., Prasad, R. B., Fex, M., Mulder, H. & Artner, I., 2021 feb. 22, I: Metabolism: Clinical and Experimental. 154734.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • protein phosphatase inhibitor-1 100%
  • Protein Phosphatase 1 96%
  • Insulin Secretion 70%
  • Glucose 44%
  • Proteins 26%

• Transcriptional analysis of islets of Langerhans from organ donors of different ages

  Seiron, P., Stenwall, A., Hedin, A., Granlund, L., Esguerra, J. L. S., Volkov, P., Renström, E., Korsgren, O., Lundberg, M. & Skog, O., 2021, I: PLoS ONE. 16, 3 March, e0247888.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Islets of Langerhans 100%
  • Tissue Donors 77%
  • Osteopontin 47%
  • Genes 40%
  • Transcriptome 36%
• 2020

  A circular RNA generated from an intron of the insulin gene controls insulin secretion

  Stoll, L., Rodríguez-Trejo, A., Guay, C., Brozzi, F., Bayazit, M. B., Gattesco, S., Menoud, V., Sobel, J., Marques, A. C., Venø, M. T., Esguerra, J. L. S., Barghouth, M., Suleiman, M., Marselli, L., Kjems, J., Eliasson, L., Renström, E., Bouzakri, K., Pinget, M., Marchetti, P., & 1 andraRegazzi, R., 2020, I: Nature Communications. 11, 1, 5611.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • RNA(circular) 100%
  • insulin 78%
  • secretions 76%
  • Circular RNAs 75%
  • genes 64%

• The TCF7L2-dependent high-voltage activated calcium channel subunit α2δ-1 controls calcium signaling in rodent pancreatic beta-cells

  Yingying, Y., Barghouth, M., Luan, C., Kazim, A., Zhou, Y., Eliasson, L., Zhang, E., Hansson, O., Thevenin, T. & Renström, E., 2020 feb. 15, I: Molecular and Cellular Endocrinology. 502, s. 1-11 110673.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Calcium Signaling 100%
  • Calcium Channels 91%
  • Insulin-Secreting Cells 91%
  • Insulin Derivative 86%
  • Insulin Secretion 84%
• 2019

  A cryptic non-GPI-anchored cytosolic isoform of CD59 controls insulin exocytosis in pancreatic β-cells by interaction with SNARE proteins

  Golec, E., Rosberg, R., Zhang, E., Renström, E., Blom, A. M. & King, B. C., 2019 nov., I: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33, 11, s. 12425-12434 10 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • SNARE Proteins 100%
  • Exocytosis 84%
  • Insulin Derivative 77%
  • Insulin Secretion 75%
  • Cell Communication 71%

• Complement Component C3 Is Highly Expressed in Human Pancreatic Islets and Prevents β Cell Death via ATG16L1 Interaction and Autophagy Regulation

  King, B., Kulak, K., Krus, U., Rosberg, R., Golec, E., wozniak, K., Gomez, M., Zhang, E., O'Connell, D. J., Renström, E. & Blom, A., 2019 jan. 8, I: Cell Metabolism. 29, 1, s. 202-210.e6

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

• Defective exocytosis and processing of insulin in a cystic fibrosis mouse model

  Edlund, A., Barghouth, M., Huhn, M., Abels, M., Esguerra, J., Mollet, I., Svedin, E., Wendt, A., Renström, E., Zhang, E., Wierup, N., Scholte, B. J., Flodström-Tullberg, M. & Eliasson, L., 2019, I: Journal of Endocrinology. 241, 1, s. 45-57

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Exocytosis 100%
  • Cystic Fibrosis Transmembrane Conductance Regulator 93%
  • Cystic Fibrosis 87%
  • Insulin 61%
  • Proinsulin 40%

• ­­­Intracellular cytosolic complement component C3 regulates cytoprotective autophagy in pancreatic beta cells by interaction with ATG16L1

  King, B. C., Renström, E. & Blom, A. M., 2019, I: Autophagy. 15, 5, s. 919-921 3 s.

  Forskningsoutput: Tidskriftsbidrag › Debate/Note/Editorial › Peer review

  • Complement C3 100%
  • Insulin-Secreting Cells 86%
  • Autophagy 77%
  • Cell Communication 75%
  • Insulin 54%

• Pancreatic β-cell mRNA modification as a marker for type 2 diabetes

  Renström, E. & Zhang, E., 2019 juli 29, I: Nature Metabolism. 1, s. 748-749 2 s.

  Forskningsoutput: Tidskriftsbidrag › Översiktsartikel

  • Type 2 Diabetes Mellitus 100%
  • Messenger RNA 75%
  • Insulin Secretion 66%
  • Methylation 60%
  • Diabetes Mellitus 52%

• Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in β Cells

  Zhang, E., Mohammed, I., Mohammed, S., Luan, C., Asplund, O., Ahmed, M., Yingying, Y., Ben-Hail, D., Soni, A., Vishnu, N., Pradeep, B., de Marinis, Y., Groop, L., Shoshan-Barmatz, V., Renström, E., Wollheim, C. & Salehi, S. A., 2019 jan. 8, I: Cell Metabolism. 29, 1, s. 64-77.e6

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

• The calcium channel subunit gamma-4 is regulated by MafA and necessary for pancreatic beta-cell specification

  Luan, C., Yingying, Y., Singh, T., Barghouth, M., Eliasson, L., Artner, I., Zhang, E. & Renström, E., 2019 mars 15, I: Communications Biology. 2, 106.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • calcium channels 100%
  • islets of Langerhans 96%
  • Calcium Channels 86%
  • Insulin-Secreting Cells 86%
  • Insulin Derivative 81%
• 2018

  Intestinal CART is a regulator of GIP and GLP-1 secretion and expression

  Shcherbina, L., Lindqvist, A., Thorén Fischer, A. H., Ahlqvist, E., Zhang, E., Falkmer, S. E., Renström, E., Koffert, J., Honka, H. & Wierup, N., 2018, I: Molecular and Cellular Endocrinology. 476, s. 8-16

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Insulinotropic 100%
  • Glucagon-Like Peptide 1 94%
  • Amphetamine 65%
  • Cocaine 60%
  • Polypeptide 49%

• Intracellular non-GPI anchored isoform of CD59 is responsible for facilitating of insulin secretion from pancreatic beta-cells

  Golec, E., Rosberg, R., Zhang, E., Netanyah, E., Renström, E., King, B. & Blom, A., 2018 sep., s. 155-156.

  Forskningsoutput: Konferensbidrag › Konferensabstract › Peer review

• MafA expression preserves immune homeostasis in human and mouse islets

  Singh, T., Sarmiento, L., Luan, C., Prasad, R. B., Johansson, J., Cataldo, L. R., Renström, E., Soneji, S., Cilio, C. & Artner, I., 2018 dec. 1, I: Genes. 9, 12, 644.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Islets of Langerhans 100%
  • Homeostasis 97%
  • Cytokines 82%
  • Maf Transcription Factors 59%
  • Coxsackievirus Infections 49%
• 2017

  A cryptic non-GPI anchored form of CD59 facilitates insulin secretion from pancreatic beta cells

  King, B. C., Golec, E., Rosberg, R., Zhang, E., O’Connell, D., Netanyah, E., Halperin, J., Renström, E. & Blom, A. M., 2017, I: Molecular Immunology. 89, s. 351-351 040.

  Forskningsoutput: Tidskriftsbidrag › Publicerat konferensabstract › Peer review

• Loss of a2d-1 calcium channel subunit function increases the susceptibility for diabetes

  Mastrolia, V., Flucher, S. M., Obermair, G. J., Drach, M., Hofer, H., Renström, E., Schwartz, A., Striessnig, J., Flucher, B. E. & Tuluc, P., 2017 apr. 1, I: Diabetes. 66, 4, s. 897-907 11 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Calcium Channels 100%
  • Insulin 63%
  • Islets of Langerhans 37%
  • Glucose Intolerance 19%
  • Insulin Resistance 15%

• Palmitoylation of Ca²⁺ channel subunit Ca_Vβ_2a induces pancreatic beta-cell toxicity via Ca²⁺ overload

  Kazim, A. S., Storm, P., Zhang, E. & Renström, E., 2017, I: Biochemical and Biophysical Research Communications. 491, 3, s. 740-746

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Palmitoylation 100%
  • Lipoylation 87%
  • Insulin-Secreting Cells 66%
  • Cell Membrane 44%
  • Plasma 37%

• Regulation of Nuclear Receptor Interacting Protein 1 (NRIP1) Gene Expression in Response to Weight Loss and Exercise in Humans

  De Marinis, Y., Sun, J., Bompada, P., Domènech Omella, J., Luan, C., Halu, A., Renström, E., Sharma, A. & Ridderstråle, M., 2017 aug. 1, I: Obesity. 25, 8, s. 1400-1409 10 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Nuclear Receptor Interacting Protein 1 100%
  • Weight Loss 41%
  • Exercise 32%
  • Gene Expression 30%
  • Skeletal Muscle 9%

• The human serum protein C4b-binding protein inhibits pancreatic IAPP-induced inflammasome activation

  Kulak, K., Westermark, G. T., Papac-Milicevic, N., Renström, E., Blom, A. M. & King, B. C., 2017, I: Diabetologia. 60, 8, s. 1522-1533

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Complement C4b-Binding Protein 100%
  • Islet Amyloid Polypeptide 85%
  • Pancreatic Polypeptide 84%
  • Inflammasomes 73%
  • Islets of Langerhans 61%
• 2016

  C4b-binding protein protects β-cells from islet amyloid polypeptide-induced cytotoxicity

  Sjölander, J., Byman, E., Kulak, K., Nilsson, S. C., Zhang, E., Krus, U., Westermark, G. T., Storm, P., King, B. C., Renström, E. & Blom, A. M., 2016 okt. 7, I: Journal of Biological Chemistry. 291, 41, s. 21644-21655 12 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Complement C4b-Binding Protein 100%
  • Islet Amyloid Polypeptide 85%
  • Polypeptide 50%
  • Protein 25%
  • Cholesterol 16%

• CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion

  Abels, M., Riva, M., Bennet, H., Ahlqvist, E., Dyachok, O., Nagaraj, V., Shcherbina, L., Fred, R. G., Poon, W., Sörhede-Winzell, M., Fadista, J., Lindqvist, A., Kask, L., Sathanoori, R., Dekker-Nitert, M., Kuhar, M. J., Ahrén, B., Wollheim, C. B., Hansson, O., Tengholm, A., & 5 andraFex, M., Renström, E., Groop, L., Lyssenko, V. & Wierup, N., 2016 juni 23, I: Diabetologia. 59, 9, s. 1928–1937 10 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Glucagon 100%
  • Insulin Secretion 95%
  • Exocytosis 29%
  • Type 2 Diabetes Mellitus 19%
  • Glucose 16%
  191 Nedladdningar (Pure)

• Elevated basal insulin secretion in type 2 diabetes caused by reduced plasma membrane cholesterol

  Nagaraj, V., Kazim, A. S., Helgeson, J., Lewold, C., Barik, S., Buda, P., Reinbothe, T. M., Wennmalm, S., Zhang, E. & Renström, E., 2016 okt. 1, I: Molecular Endocrinology. 30, 10, s. 1059-1069 11 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Insulin Secretion 100%
  • Type 2 Diabetes Mellitus 75%
  • Cholesterol 74%
  • Cell Membrane 73%
  • Membranes 47%

• HMGB1 binds to the rs7903146 locus in TCF7L2 in human pancreatic islets.

  Zhou, Y., Oskolkov, N., Shcherbina, L., Ratti, J., Kock, K-H., Su, J., Martin, B., Zackrisson Oskolkova, M., Göransson, O., Bacon, J., Li, W., Bucciarelli, S., Cilio, C., Brazma, A., Thatcher, B., Rung, J., Wierup, N., Renström, E., Groop, L. & Hansson, O., 2016, I: Molecular and Cellular Endocrinology. 430, s. 138-145 8 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • High Mobility Group Proteins 100%
  • TCF Transcription Factors 94%
  • Factor VII 88%
  • Islets of Langerhans 69%
  • Alleles 50%

• MafA-Controlled Nicotinic Receptor Expression Is Essential for Insulin Secretion and Is Impaired in Patients with Type 2 Diabetes.

  Ganic, E., Singh, T., Luan, C., Fadista, J., Johansson, J., Cyphert, H. A., Bennet, H., Storm, P., Prost, G., Ahlenius, H., Renström, E., Stein, R., Groop, L., Fex, M. & Artner, I., 2016, I: Cell Reports. 14, 8, s. 1991-2002

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Nicotinic Receptors 100%
  • Insulin Derivative 92%
  • Insulin Secretion 90%
  • Type 2 Diabetes Mellitus 68%
  • Neurotransmitter 60%
• 2015

  Complement inhibitor CD55 governs the integrity of membrane rafts in pancreatic beta cells, but plays no role in insulin secretion.

  Nagaraj, V., King, B., Storm, P., Vikman, P., Ottosson Laakso, E., Blom, A. & Renström, E., 2015, I: Biochemical and Biophysical Research Communications. 460, 3, s. 518-524

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Complement Inhibitor 100%
  • Complement Inactivating Agents 82%
  • Insulin-Secreting Cells 60%
  • Insulin Derivative 57%
  • Insulin Secretion 56%
  156 Nedladdningar (Pure)

• Neutrophil Extracellular Traps Induce Trypsin Activation, Inflammation, and Tissue Damage in Mice with Severe Acute Pancreatitis.

  Merza, M., Hartman Magnusson, H., Rahman, M., Hwaiz, R., Zhang, E., Renström, E., Luo, L., Mörgelin, M., Regnér, S. & Thorlacius, H., 2015, I: Gastroenterology. 149, 7, s. 1920

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Extracellular Traps 100%
  • Trypsin 72%
  • Pancreatitis 68%
  • Neutrophils 55%
  • Inflammation 41%

• Pancreatic beta cell dedifferentiation involves the voltage-gated calcium channel subunit gamma4

  Luan, C., GANIC, ELVIRA., Artner, I., Zhang, E. & Renström, E., 2015 aug. 12, I: Diabetologia. 58, S1, s. S208-S209 418.

  Forskningsoutput: Tidskriftsbidrag › Publicerat konferensabstract › Peer review

  Öppen tillgång
• 2014

  Dynamic Magnetic Fields Remote-Control Apoptosis via Nanoparticle Rotation.

  Zhang, E., Kircher, M. F., Koch, M., Eliasson, L., Goldberg, S. N. & Renström, E., 2014, I: ACS Nano. 8, 4, s. 3192-3201

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Cell death 100%
  • remote control 94%
  • apoptosis 93%
  • Iron Oxide Nanoparticle 74%
  • Remote control 69%

• Genotype-based treatment of type 2 diabetes with an α2A-adrenergic receptor antagonist.

  Tang, Y., Axelsson, A., Spégel, P., Andersson, L., Mulder, H., Groop, L., Renström, E. & Rosengren, A., 2014, I: Science Translational Medicine. 6, 257, s. 257ra139

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Adrenergic Antagonists 100%
  • Type 2 Diabetes Mellitus 60%
  • Genotype 57%
  • Insulin Secretion 53%
  • Yohimbine 43%

• Glioma Cell Proliferation Controlled by ERK Activity-Dependent Surface Expression of PDGFRA.

  Chen, D., Zuo, D., Luan, C., Min, L., Na, M., Ran, L., Sun, Y., Persson, A., Englund, E., Salford, L., Renström, E., Fan, X. & Zhang, E., 2014, I: PLoS ONE. 9, 1, e87281.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Glioma 100%
  • Cell Proliferation 71%
  • U 0126 56%
  • macrogolgin 17%
  • Cell Line 16%
  607 Nedladdningar (Pure)

• Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism.

  Fadista, J., Vikman, P., Ottosson Laakso, E., Mollet, I., Esguerra, J., Taneera, J., Storm, P., Osmark, P., Ladenvall, C., Prasad, R., Hansson, K. B., Finotello, F., Uvebrant, K., Ofori, J., Di Camillo, B., Krus, U., Cilio, C., Hansson, O., Eliasson, L., Rosengren, A., & 3 andraRenström, E., Wollheim, C. & Groop, L., 2014, I: Proceedings of the National Academy of Sciences. 111, 38, s. 13924-13929

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Islets of Langerhans 100%
  • Type 2 Diabetes Mellitus 74%
  • Glucose 62%
  • Allelic Imbalance 59%
  • Catalogs 49%

• TCF7L2 is a master regulator of insulin production and processing.

  Zhou, Y., Park, S-Y., Su, J., Bailey, K., Ottosson Laakso, E., Shcherbina, L., Oskolkov, N., Zhang, E., Thevenin, T., Fadista, J., Bennet, H., Vikman, P., Wierup, N., Fex, M., Rung, J., Wollheim, C., Nobrega, M., Renström, E., Groop, L. & Hansson, O., 2014, I: Human Molecular Genetics. 23, 24, s. 6419-6431

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Proinsulin 100%
  • Type 2 Diabetes Mellitus 55%
  • Gene Regulatory Networks 53%
  • Insulin 50%
  • Islets of Langerhans 49%

• The Complement Inhibitor CD59 Regulates Insulin Secretion by Modulating Exocytotic Events.

  Krus, U., King, B., Nagaraj, V., Gandasi, N. R., Sjölander, J., Buda, P., Garcia Vaz, E., Gomez, M., Ottosson Laakso, E., Storm, P., Fex, M., Vikman, P., Zhang, E., Barg, S., Blom, A. & Renström, E., 2014, I: Cell Metabolism. 19, 5, s. 883-890

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Complement Inactivating Agents 100%
  • Insulin Secretion 68%
  • Innate Immunity 63%
  • Vesicle-Associated Membrane Protein 2 53%
  • Syntaxin 1 52%
  496 Nedladdningar (Pure)
• 2013

  Effect of Common Genetic Variants Associated with Type 2 Diabetes and Glycemic Traits on α- and β-cell Function and Insulin Action in Man.

  Jonsson, A., Ladenvall, C., Ahluwalia, T. S., Kravic, J., Krus, U., Taneera, J., Isomaa, B., Tuomi, T., Renström, E., Groop, L. & Lyssenko, V., 2013, I: Diabetes. 62, 8, s. 2978-2983

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Glucagon 100%
  • Type 2 Diabetes Mellitus 72%
  • Insulin 65%
  • Insulin Secretion 38%
  • In Vitro Techniques 33%

• Eukaryotic translation initiation factor 3 subunit e controls intracellular calcium homeostasis by regulation of cav1.2 surface expression.

  Buda, P., Reinbothe, T., Nagaraj, V., Mahdi, T., Luan, C., Tang, Y., Axelsson, A., Li, D., Rosengren, A., Renström, E. & Zhang, E., 2013, I: PLoS ONE. 8, 5, e64462.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Prokaryotic Initiation Factor-3 100%
  • Eukaryotic Initiation Factor-3 98%
  • Eukaryotic Initiation Factors 77%
  • Homeostasis 42%
  • Calcium 39%
  219 Nedladdningar (Pure)

• Expression profiling of cell cycle genes in human pancreatic islets with and without type 2 diabetes.

  Taneera, J., Fadista, J., Ahlqvist, E., Zhang, M., Wierup, N., Renström, E. & Groop, L., 2013, I: Molecular and Cellular Endocrinology. 375, 1-2, s. 35-42

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • cdc Genes 100%
  • Cyclin-Dependent Kinases 91%
  • Microarrays 84%
  • Cyclin Dependent Kinase Inhibitor 84%
  • Islets of Langerhans 78%

• The human L-type calcium channel Ca(v)1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes.

  Reinbothe, T., Alkayyali, S., Ahlqvist, E., Tuomi, T., Isomaa, B., Lyssenko, V. & Renström, E., 2013, I: Diabetologia. 56, 2, s. 340-349

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • L-Type Calcium Channels 100%
  • Insulin 53%
  • Type 2 Diabetes Mellitus 38%
  • Insulin Secretion 38%
  • Single Nucleotide Polymorphism 32%
  613 Nedladdningar (Pure)
• 2012

  A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.

  Taneera, J., Lang, S., Sharma, A., Fadista, J., Zhou, Y., Ahlqvist, E., Jonsson, A., Lyssenko, V., Vikman, P., Hansson, O., Parikh, H., Korsgren, O., Soni, A., Krus, U., Zhang, E., Jing, X., Esguerra, J., Wollheim, C., Salehi, S. A., Rosengren, A., & 2 andraRenström, E. & Groop, L., 2012, I: Cell Metabolism. 16, 1, s. 122-134

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Type 2 Diabetes Mellitus 100%
  • Genes 53%
  • Insulin Secretion 44%
  • Protein Interaction Maps 27%
  • Genetic Loci 27%

• Impact of transcription factor 7-like 2 (TCF7L2) on pancreatic islet function and morphology in mice and men.

  Renström, E., 2012, I: Diabetologia. 55, 10, s. 2559-2561

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • T Cell Transcription Factor 1 100%
  • Islets of Langerhans 63%
  • Genetic Variation 30%
  • Publications 26%
  • Type 2 Diabetes Mellitus 23%
  133 Nedladdningar (Pure)