Helena Liljedahl

Sökresultat

• 2021

  A gene expression-based single sample predictor of lung adenocarcinoma molecular subtype and prognosis

  Liljedahl, H., Karlsson, A., Oskarsdottir, G. N., Salomonsson, A., Brunnström, H., Erlingsdottir, G., Jönsson, M., Isaksson, S., Arbajian, E., Ortiz-Villalón, C., Hussein, A., Bergman, B., Vikström, A., Monsef, N., Branden, E., Koyi, H., de Petris, L., Patthey, A., Behndig, A. F., Johansson, M., & 2 andraPlanck, M. & Staaf, J., 2021 jan. 1, I: International Journal of Cancer. 148, 1, s. 238-251 14 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Adenocarcinoma of Lung 100%
  • Atlases 66%
  • Gene Expression 56%
  • Survival 51%
  • Genome 42%

• Pan-cancer application of a lung-adenocarcinoma-derived gene-expression-based prognostic predictor

  Nacer, D. F., Liljedahl, H., Karlsson, A. F., Lindgren, D. & Staaf, J., 2021, I: Briefings in Bioinformatics. 22, 6, bbab154.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Gene expression 100%
  • Adenocarcinoma of Lung 97%
  • Classifiers 64%
  • Tumors 56%
  • Gene Expression 54%
• 2019

  A combined gene expression tool for parallel histological prediction and gene fusion detection in non-small cell lung cancer

  Karlsson, A., Cirenajwis, H., Ericson-Lindquist, K., Brunnström, H., Reuterswärd, C., Jönsson, M., Ortiz-Villalón, C., Hussein, A., Bergman, B., Vikström, A., Monsef, N., Branden, E., Koyi, H., de Petris, L., Micke, P., Patthey, A., Behndig, A. F., Johansson, M., Planck, M. & Staaf, J., 2019 mars 26, I: Scientific Reports. 9, 1, 5207.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Gene Fusion 100%
  • Non-Small Cell Lung Carcinoma 79%
  • Histology 69%
  • Gene Expression 52%
  • Large Cell Carcinoma 46%

• Performance of gene expression-based single sample predictors for assessment of clinicopathological subgroups and molecular subtypes in cancers: a case comparison study in non-small cell lung cancer

  Cirenajwis, H., Lauss, M., Planck, M., Vallon-Christersson, J. & Staaf, J., 2019 feb. 4, I: Briefings in Bioinformatics. 21, 2, s. 729–740 12 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Gene expression 100%
  • Cells 88%
  • Non-Small Cell Lung Carcinoma 81%
  • Case-Control Studies 73%
  • Genes 69%

• Pre-operative plasma cell-free circulating tumor DNA and serum protein tumor markers as predictors of lung adenocarcinoma recurrence

  Isaksson, S., George, A. M., Jönsson, M., Cirenajwis, H., Jönsson, P., Bendahl, P. O., Brunnström, H., Staaf, J., Saal, L. H. & Planck, M., 2019, I: Acta Oncologica. 58, 8, s. 1079-1086 9 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Circulating Tumor DNA 100%
  • Adenocarcinoma of Lung 74%
  • Plasma Cells 69%
  • Tumor Biomarkers 67%
  • Blood Proteins 61%
• 2017

  NF1-mutated melanoma tumors harbor distinct clinical and biological characteristics

  Cirenajwis, H., Lauss, M., Ekedahl, H., Törngren, T., Kvist, A., Saal, L. H., Olsson, H., Staaf, J., Carneiro, A., Ingvar, C., Harbst, K., Hayward, N. K. & Jönsson, G. B., 2017 apr., I: Molecular Oncology. 11, 4, s. 438-451 14 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Melanoma 100%
  • Mutation 53%
  • Neoplasms 38%
  • Uveal melanoma 31%
  • Sunlight 29%
• 2016

  Multiregion whole-exome sequencing uncovers the genetic evolution and mutational heterogeneity of early-stage metastatic melanoma

  Harbst, K., Lauss, M., Cirenajwis, H., Isaksson, K., Rosengren, F., Törngren, T., Kvist, A., Johansson, M. C., Vallon-Christersson, J., Baldetorp, B., Borg, Å., Olsson, H., Ingvar, C., Carneiro, A. & Jönsson, G. B., 2016 aug. 15, I: Cancer Research. 76, 16, s. 4765-4774 10 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Molecular Evolution 100%
  • Whole Exome Sequencing 92%
  • Melanoma 64%
  • Mutation 34%
  • Neoplasms 25%
• 2015

  A role for antizyme inhibitor in cell proliferation.

  Silva, T., Cirenajwis, H., Wallace, H. M., Oredsson, S. & Persson, L., 2015, I: Amino Acids. 47, 7, s. 1341-1352

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Polyamines 100%
  • Polyamine 90%
  • Cell Proliferation 55%
  • Ornithine Decarboxylase 40%
  • Ornithine 39%
  179 Nedladdningar (Pure)

• Genome-Wide DNA Methylation Analysis in Melanoma Reveals the Importance of CpG Methylation in MITF Regulation.

  Lauss, M., Haq, R., Cirenajwis, H., Phung, B., Harbst, K., Staaf, J., Rosengren, F., Holm, K., Aine, M., Jirström, K., Borg, Å., Busch, C., Geisler, J., Eystein Lønning, P., Ringnér, M., Howlin, J., Fisher, D. & Jönsson, G. B., 2015, I: Journal of Investigative Dermatology. 135, 7, s. 1820-1828

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Microphthalmia-Associated Transcription Factor 100%
  • DNA Methylation 66%
  • Methylation 60%
  • Melanoma 55%
  • Genome 45%

• Loss of CITED1, an MITF regulator, drives a phenotype switch in vitro and can predict clinical outcome in primary melanoma tumours.

  Howlin, J., Cirenajwis, H., Lettiero, B., Staaf, J., Lauss, M., Saal, L., Borg, K., Gruvberger, S. & Jönsson, G. B., 2015, I: PeerJ. 3, e788.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Proliferative 100%
  • Silencing RNA 96%
  • melanoma 86%
  • Melanoma 62%
  • small interfering RNA 57%
  273 Nedladdningar (Pure)

• Molecular stratification of metastatic melanoma using gene expression profiling: prediction of survival outcome and benefit from molecular targeted therapy.

  Cirenajwis, H., Ekedahl, H., Lauss, M., Harbst, K., Carneiro, A., Enoksson, J., Rosengren, F., Werner Hartman, L., Törngren, T., Kvist, A., Fredlund, E., Bendahl, P-O., Jirström, K., Lundgren, L., Howlin, J., Borg, Å., Gruvberger, S., Saal, L., Nielsen, K., Ringnér, M., & 5 andraTsao, H., Olsson, H., Ingvar, C., Staaf, J. & Jönsson, G. B., 2015, I: Oncotarget. 6, 14, s. 12297-12309

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Molecular Targeted Therapy 100%
  • Gene Expression Profiling 76%
  • Melanoma 61%
  • Survival 40%
  • Phenotype 25%
  405 Nedladdningar (Pure)

• Mutational and gene fusion analyses of primary large cell and large cell neuroendocrine lung cancer.

  Karlsson, A. K., Brunnström, H., Ericson Lindquist, K., Jirström, K., Jönsson, M., Rosengren, F., Reuterswärd, C., Cirenajwis, H., Borg, Å., Jönsson, P., Planck, M., Jönsson, G. B. & Staaf, J., 2015, I: Oncotarget. 6, 26, s. 22028-22037

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Neuroendocrine Cells 100%
  • Gene Fusion 89%
  • Lung Neoplasms 62%
  • Mutation 44%
  • Adenocarcinoma 37%
  235 Nedladdningar (Pure)
• 2014

  Molecular and genetic diversity in the metastatic process of melanoma.

  Harbst, K., Lauss, M., Cirenajwis, H., Winter, C., Howlin, J., Törngren, T., Kvist, A., Nodin, B., Olsson, E., Häkkinen, J., Jirström, K., Staaf, J., Lundgren, L., Olsson, H., Ingvar, C., Gruvberger, S., Saal, L. & Jönsson, G. B., 2014, I: Journal of Pathology. 233, 1, s. 39-50

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Genetic Variation 100%
  • Melanoma 85%
  • Molecular Biology 83%
  • Neoplasm Metastasis 31%
  • Neoplasms 29%
• 2013

  The clinical significance of BRAF and NRAS mutations in a clinic-based metastatic melanoma cohort.

  Ekedahl, H., Cirenajwis, H., Harbst, K., Carneiro, A., Nielsen, K., Olsson, H., Lundgren, L., Ingvar, C. & Jönsson, G., 2013, I: British Journal of Dermatology. 169, 5, s. 1049-1055

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Melanoma 100%
  • Mutation 67%
  • Neoplasms 38%
  • Therapeutics 19%
• 2011

  The antiproliferative effect of dietary fibre phenolic compounds ferulic acid and p-coumaric acid on the cell cycle in Caco-2 cells

  Janicke, B., Hegardt, C., Krogh, M., Önning, G., Åkesson, B., Cirenajwis, H. & Oredsson, S., 2011, I: Nutrition and Cancer. 63, s. 611-622 12 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • trans-3-(4'-hydroxyphenyl)-2-propenoic acid 100%
  • ferulic acid 90%
  • Dietary Fiber 76%
  • Caco-2 Cells 74%
  • Cell Cycle 49%
• 2010

  Reduction of the putative CD44+CD24- breast cancer stem cell population by targeting the polyamine metabolic pathway with PG11047.

  Cirenajwis, H., Smiljanic, S., Honeth, G., Hegardt, C., Marton, L. J. & Oredsson, S., 2010, I: Anti-Cancer Drugs. 21, 10, s. 897-906

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Polyamines 100%
  • Neoplastic Stem Cells 89%
  • Metabolic Networks and Pathways 85%
  • Eflornithine 81%
  • Breast Neoplasms 53%