Inga-Maria Frick

Sökresultat

• 2021

  Lack of Opsonic Antibody Responses to Invasive Infections With Streptococcus dysgalactiae

  Bläckberg, A., de Neergaard, T., Frick, I. M., Nordenfelt, P., Lood, R. & Rasmussen, M., 2021 apr. 27, I: Frontiers in Microbiology. 12, 635591.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Streptococcus 100%
  • Antibody Formation 87%
  • Bacteremia 82%
  • Antibodies 53%
  • Infections 46%

• Streptococcal protein SIC activates monocytes and induces inflammation

  Neumann, A., Happonen, L., Karlsson, C., Bahnan, W., Frick, I. M. & Björck, L., 2021 apr. 23, I: iScience. 24, 4, 102339.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Complement Inactivating Agents 100%
  • Monocytes 56%
  • Inflammation 40%
  • Streptococcus pyogenes 33%
  • Proteins 25%

• Vaccine-induced, but not natural immunity, against the Streptococcal inhibitor of complement protects against invasive disease

  Tan, L. K. K., Reglinski, M., Teo, D., Reza, N., Lamb, L. E. M., Nageshwaran, V., Turner, C. E., Wikstrom, M., Frick, I. M., Bjorck, L. & Sriskandan, S., 2021 dec., I: npj Vaccines. 6, 62.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Complement Inactivating Agents 100%
  • Innate Immunity 63%
  • Vaccines 51%
  • Streptococcus pyogenes 27%
  • Antibodies 18%
• 2020

  Finegoldia magna, an Anaerobic Gram-Positive Bacterium of the Normal Human Microbiota, Induces Inflammation by Activating Neutrophils

  Neumann, A., Björck, L. & Frick, I. M., 2020, I: Frontiers in Microbiology. 11, 65.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Anaerobic Bacteria 100%
  • Gram-Positive Bacteria 88%
  • Microbiota 80%
  • Neutrophils 63%
  • Inflammation 47%
• 2018

  Protein SIC secreted from Streptococcus pyogenes forms complexes with extracellular histones that boost cytokine production

  Westman, J., Chakrakodi, B., Snäll, J., Mörgelin, M., Madsen, M. B., Hyldegaard, O., Neumann, A., Frick, I. M., Norrby-Teglund, A., Björck, L. & Herwald, H., 2018 feb. 22, I: Frontiers in Immunology. 9, FEB, s. 1-14 236.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Streptococcus pyogenes 100%
  • Histones 76%
  • Cytokines 50%
  • Proteins 30%
  • Complement Inactivating Agents 17%

• Streptococcal inhibitor of complement (SIC) modulates fibrinolysis and enhances bacterial survival within fibrin clots

  Frick, I. M., Shannon, O., Neumann, A., Karlsson, C., Wikström, M. & Björck, L., 2018, I: Journal of Biological Chemistry. 293, 35, s. 13578-13591 14 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Complement Inactivating Agents 100%
  • Fibrin 82%
  • Fibrinolysis 75%
  • Survival 37%
  • Protein 28%
• 2016

  Group G streptococci mediate fibrinogendependent platelet aggregation leading to transient entrapment in platelet aggregates

  Svensson, L., Frick, I-M. & Shannon, O., 2016 jan. 1, I: Microbiology. 162, 1, s. 117-126 10 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Streptococcus 100%
  • Platelet Aggregation 98%
  • Blood Platelets 76%
  • Bacteria 39%
  • Fibrinogen Receptors 30%

• Saliva-Induced Clotting Captures Streptococci: Novel Roles for Coagulation and Fibrinolysis in Host Defense and Immune Evasion

  Wollein Waldetoft, K., Mohanty, T., Karlsson, C., Mörgelin, M., Frick, I-M., Malmström, J. & Björck, L., 2016 okt., I: Infection and Immunity. 84, 10, s. 2813-23 11 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • pharyngitis 100%
  • immune evasion 96%
  • fibrinolysis 90%
  • Immune Evasion 82%
  • Pharyngitis 76%

• Structure and Interactions of a Dimeric Variant of sHIP, a Novel Virulence Determinant of Streptococcus pyogenes.

  Diehl, C., Wisniewska, M., Frick, I-M., Streicher, W., Björck, L., Malmström, J. & Wikström, M., 2016, I: Frontiers in Microbiology. 7, 95.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Streptococcus pyogenes 100%
  • Virulence 71%
  • histidine-rich proteins 54%
  • Proteins 30%
  • Helix-Loop-Helix Motifs 18%
• 2014

  Expression of MIG/CXCL9 in Cystic Fibrosis and Modulation of Its Activities by Elastase of Pseudomonas aeruginosa.

  Jovic, S., Shikhagaie, M., Mörgelin, M., Kjellström, S., Erjefält, J., Olin, A., Frick, I-M. & Egesten, A., 2014, I: Journal of Innate Immunity. 6, 6, s. 846-859

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Pseudomonas aeruginosa pseudolysin 100%
  • Cystic Fibrosis 55%
  • Pseudomonas aeruginosa 37%
  • Sputum 23%
  • Chemokine CXCL9 13%

• Functional and Structural Properties of a Novel Protein and Virulence Factor (sHIP) in Streptococcus pyogenes.

  Wisniewska, M., Happonen, L., Kahn, F., Varjosalo, M., Malmström, L., Rosenberger, G., Karlsson, C., Cazzamali, G., Pozdnyakova, I., Frick, I-M., Björck, L., Streicher, W., Malmström, J. & Wikström, M., 2014, I: Journal of Biological Chemistry. 289, 26, s. 18175-18188

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • histidine-rich proteins 100%
  • Virulence Factor 89%
  • Streptococcus pyogenes 79%
  • Virulence Factors 67%
  • Glycoprotein 59%

• Identification of molecular mechanisms used by Finegoldia magna to penetrate and colonise human skin.

  Murphy, E., Mörgelin, M., Reinhardt, D. P., Olin, A., Björck, L. & Frick, I-M., 2014, I: Molecular Microbiology. 94, 2, s. 403-417

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Skin 100%
  • Collagen 69%
  • Basement Membrane 59%
  • Fibrillins 47%
  • Subtilisin 43%

• Identification of pili on the surface of Finegoldia magna - A Gram-positive anaerobic cocci.

  Murphy, E., Janulczyk, R., Karlsson, C., Mörgelin, M. & Frick, I-M., 2014, I: Anaerobe. 27, Mar 29, s. 40-49

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Gram-Positive Cocci 100%
  • Immune Sera 34%
  • Proteins 28%
  • Host Microbial Interactions 24%
  • Skin 21%
  183 Nedladdningar (Pure)

• Substrate profiling of Finegoldia magna SufA protease, inhibitor screening and application to prevent human fibrinogen degradation and bacteria growth in vitro.

  Burchacka, E., Sieńczyk, M., Frick, I-M., Wysocka, M., Lesner, A. & Oleksyszyn, J., 2014, I: Biochimie. 103C, May 22, s. 137-143

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Magnon 100%
  • Fibrinolysin 85%
  • Protease Inhibitor 84%
  • Protease Inhibitors 74%
  • Fibrinogen 69%

• Surface proteins of the Group G Streptococcus in different phases of growth: patterns of production and implications for the host-bacteria relationship.

  Wollein Waldetoft, K., Karlsson, C., Gram, M., Malmström, J., Mörgelin, M., Frick, I-M. & Björck, L., 2014, I: Microbiology. 160, Nov 12, s. 279-286

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Streptococcus 100%
  • Membrane Proteins 80%
  • Bacteria 65%
  • Growth 49%
  • Proteins 35%
• 2013

  Binding of complement inhibitor C4b-binding protein to a highly virulent S. pyogenes M1 strain is mediated by protein H and enhances adhesion to and invasion of endothelial cells.

  Ermert, D., Weckel, A., Agarwal, V., Frick, I-M., Björck, L. & Blom, A., 2013, I: Journal of Biological Chemistry. 288, 45, s. 32172-32183

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Complement Inhibitor 100%
  • Complement C4b-Binding Protein 92%
  • Complement Inactivating Agents 82%
  • Endothelial Cells 41%
  • Strain 39%
  143 Nedladdningar (Pure)

• FAF and SufA: Proteins of Finegoldia magna That Modulate the Antibacterial Activity of Histones.

  Murphy, E., Mohanty, T. & Frick, I-M., 2013, I: Journal of Innate Immunity.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Histones 100%
  • Proteins 39%
  • Skin 35%
  • DNA Packaging 31%
  • Subtilisin 30%
• 2012

  Streptococcal surface proteins activate the contact system and control its antibacterial activity.

  Wollein Waldetoft, K., Svensson, L., Mörgelin, M., Olin, A., Nitsche, P., Björck, L. & Frick, I-M., 2012, I: Journal of Biological Chemistry. 287, 30, s. 25010-25018

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Membrane Proteins 100%
  • Antibacterial 99%
  • Streptococcus 82%
  • N-acetyltalosaminuronic acid 62%
  • Coagulants 52%
  238 Nedladdningar (Pure)
• 2011

  Activation of the contact system at the surface of Fusobacterium necrophorum: a possible virulence mechanism in Lemierre's syndrome.

  Holm, K., Frick, I-M., Björck, L. & Rasmussen, M., 2011, I: Infection and Immunity. 79, 8, s. 3284-3290

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Lemierre Syndrome 100%
  • Fusobacterium necrophorum 99%
  • Factor XI 67%
  • Virulence 53%
  • virulence 49%

• Antibacterial activity of the contact and complement systems is blocked by SIC, a protein secreted by Streptococcus pyogenes.

  Frick, I-M., Shannon, O., Åkesson, P., Mörgelin, M., Collin, M., Schmidtchen, A. & Björck, L., 2011, I: Journal of Biological Chemistry. 286, s. 1331-1340

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Streptococcus pyogenes 100%
  • Polypeptide Antibiotic Agent 89%
  • Antibacterial 67%
  • Serogroup 59%
  • Complement Activation 37%
  136 Nedladdningar (Pure)

• Binding of albumin promotes bacterial survival at the epithelial surface.

  Egesten, A., Frick, I-M., Mörgelin, M., Olin, A. & Björck, L., 2011, I: Journal of Biological Chemistry. Dec, s. 2469-2476

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Streptococcus 100%
  • Albumins 83%
  • Survival 54%
  • Carrier Proteins 49%
  • Protein 40%
  238 Nedladdningar (Pure)

• Constitutive and Inflammation-Dependent Antimicrobial Peptides Produced by Epithelium Are Differentially Processed and Inactivated by the Commensal Finegoldia magna and the Pathogen Streptococcus pyogenes.

  Frick, I-M., Nordin, S. L., Baumgarten, M., Mörgelin, M., Sørensen, O. E., Olin, A. & Egesten, A., 2011, I: Journal of immunology. 187, s. 4300-4309

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Midkine 100%
  • Streptococcus pyogenes 78%
  • Epithelium 48%
  • Peptides 40%
  • Inflammation 37%

• Interaction of Bacteroides fragilis and Bacteroides thetaiotaomicron with the kallikrein-kinin system

  Murphy, E., Mörgelin, M., Cooney, J. C. & Frick, I-M., 2011, I: Microbiology. 157, s. 2094-2105

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Bacteroides thetaiotaomicron 100%
  • Kallikrein-Kinin System 87%
  • Bacteroides fragilis 80%
  • Bacteroides 76%
  • Kininogens 44%
• 2009

  SufA - a bacterial enzyme that cleaves fibrinogen and blocks fibrin network formation.

  Karlsson, C., Mörgelin, M., Collin, M., Lood, R., Andersson, M-L., Schmidtchen, A., Björck, L. & Frick, I-M., 2009, I: Microbiology. 155, Pt 1, s. 238-248

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Fibrin 100%
  • Fibrinogen 93%
  • Bacteria 65%
  • Enzymes 53%
  • Gene Targeting 22%

• SufA of the opportunistic pathogen Finegoldia magna modulates actions of the antibacterial chemokine MIG/CXCL9, promoting bacterial survival during epithelial inflammation.

  Karlsson, C., Eliasson, M., Olin, A., Mörgelin, M., Karlsson, A., Malmsten, M., Egesten, A. & Frick, I-M., 2009, I: Journal of Biological Chemistry. 284, s. 29499-29508

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Chemokine CXCL9 100%
  • Magnon 83%
  • Streptococcus pyogenes 49%
  • Keratinocytes 39%
  • Inflammation 35%
• 2008

  Identification of a novel protein promoting the colonization and survival of Finegoldia magna, a bacterial commensal and opportunistic pathogen.

  Frick, I-M., Karlsson, C., Mörgelin, M., Olin, A. I., Janjusevic, R., Hammarström, C., Holst, E., de Château, M. & Björck, L., 2008, I: Molecular Microbiology. 70, s. 695-708

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Basement Membrane 100%
  • Survival 84%
  • Osteonectin 74%
  • Protein Aggregates 64%
  • Anaerobic Bacteria 62%
• 2007

  Group G streptococcal IgG binding molecules FOG and protein G have different impacts on opsonization by C1q

  Nitsche-Schmitz, D. P., Linge, H., Sastalla, I., Reissmann, S., Frick, I-M. & Chhatwal, G. S., 2007, I: Journal of Biological Chemistry. 282, 24, s. 17530-17536

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Immunoglobulin G 100%
  • Protein 54%
  • Proteins 48%
  • Molecule 45%
  • Virulence Factor 26%

• Identification of a streptococcal octapeptide motif involved in acute rheumatic fever

  Dinkla, K., Nitsche-Schmitz, D. P., Barroso, V., Reissmann, S., Linge, H., Frick, I-M., Rohde, M. & Chhatwal, G. S., 2007, I: Journal of Biological Chemistry. 282, 26, s. 18686-18693

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Rheumatic Fever 100%
  • Collagen 74%
  • Protein 24%
  • Streptococcus 24%
  • Strain 13%

• M1 protein of Streptococcus pyogenes increases production of the antibacterial CXC chemokine MIG/CXCL9 in pharyngeal epithelial cells

  Eliasson, M., Frick, I-M., Collin, M., Sørensen, O. E., Björck, L. & Egesten, A., 2007, I: Microbial Pathogenesis. 43, 5-6, s. 224-233

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Chemokine CXCL9 100%
  • CXC Chemokines 77%
  • Streptococcus pyogenes 74%
  • Epithelial Cells 43%
  • NF-kappa B 32%

• Protein FOG is a moderate inducer of MIG/CXCL9, and group G streptococci are more tolerant than group A streptococci to this chemokine's antibacterial effect

  Linge, H., Sastalla, I., Nitsche-Schmitz, D. P., Egesten, A. & Frick, I-M., 2007, I: Microbiology. 153, s. 3800-3808

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Streptococcus 100%
  • Chemokines 91%
  • Proteins 35%
  • Chemokine CXCL9 32%
  • Leukocyte Elastase 25%

• SufA--a novel subtilisin-like serine proteinase of Finegoldia magna.

  Karlsson, C., Andersson, M-L., Collin, M., Schmidtchen, A., Björck, L. & Frick, I-M., 2007, I: Microbiology. 153, Pt 12, s. 4208-4218

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Subtilisin 100%
  • Serine Proteases 78%
  • proteinase F 52%
  • Chemokine CXCL9 38%
  • Enzymes 38%

• The CXC Chemokine MIG/CXCL9 Is Important in Innate Immunity against Streptococcus pyogenes.

  Egesten, A., Eliasson, M., Linge, H., Olin, A., Mörgelin, M., Mueller, A., Pease, J. E., Frick, I-M. & Björck, L., 2007, I: Journal of Infectious Diseases. 195, 5, s. 684-693

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

• The dual role of the contact system in bacterial infectious disease

  Frick, I-M., Björck, L. & Herwald, H., 2007, I: Thrombosis and Haemostasis. 98, 3, s. 497-502

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
• 2006

  Streptococcal protein fog: A novel matrix adhesin interacting with colagen I in vivo.

  Nitsche, P., Linge, H., Frick, I-M. & Mörgelin, M., 2006, I: Journal of Biological Chemistry. 281, 3, s. 1670-1679

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Fog 100%
  • Weather 87%
  • Collagen 66%
  • Streptococcus 53%
  • Skin 38%
  132 Nedladdningar (Pure)

• The contact system-a novel branch of innate immunity generating antibacterial peptides.

  Frick, I-M., Åkesson, P., Herwald, H., Mörgelin, M., Malmsten, M., Nagler, D. K. & Björck, L., 2006, I: EMBO Journal. 25, 23, s. 5569-5578

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Polypeptide Antibiotic Agent 100%
  • Innate Immunity 83%
  • LL-37 77%
  • High Molecular Weight Kininogens 69%
  • CAP18 lipopolysaccharide-binding protein 65%
• 2004

  Crystal structure and biological implications of a bacterial albumin binding module in complex with human serum albumin

  Lejon, S., Frick, I-M., Björck, L., Wikstrom, M. & Svensson, S., 2004, I: Journal of Biological Chemistry. 279, 41, s. 42924-42928

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Human Serum Albumin 100%
  • Albumins 72%
  • Crystal Structure 42%
  • Protein 35%
  • Magnon 33%

• Protein FOG - a streptococcal inhibitor of neutrophil function.

  Linge, H., Mörgelin, M. & Frick, I-M., 2004, I: Microbiology. 150, Pt 12, s. 4211-4221

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Neutrophils 100%
  • Fibrinogen 87%
  • Streptococcus 74%
  • Streptococcus IgG Fc-binding protein 65%
  • Proteins 46%
  164 Nedladdningar (Pure)
• 2003

  Interactions between M proteins of Streptococcus pyogenes and glycosaminoglycans promote bacterial adhesion to host cells.

  Frick, I-M., Schmidtchen, A. & Sjöbring, U., 2003, I: European Journal of Biochemistry. 270, 10, s. 2303-2311

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Bacterial Adhesion 100%
  • Streptococcus pyogenes 90%
  • Glycosaminoglycan 86%
  • Glycosaminoglycans 78%
  • Dermatan Sulfate 74%
  165 Nedladdningar (Pure)

• SIC - a secreted protein of Streptococcus pyogenes that inactivates antibacterial peptides.

  Frick, I-M., Åkesson, P., Rasmussen, M., Schmidtchen, A. & Björck, L., 2003, I: Journal of Biological Chemistry. 278, 19, s. 16561-16566

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång
• 2002

  Proteinases of common pathogenic bacteria degrade and inactivate the antibacterial peptide LL-37

  Schmidtchen, A., Frick, I-M., Andersson, E., Tapper, H. & Björck, L., 2002, I: Molecular Microbiology. 46, 1, s. 157-168

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Pseudomonas aeruginosa pseudolysin 100%
  • CAP18 lipopolysaccharide-binding protein 81%
  • Proteus mirabilis 48%
  • Peptide Hydrolases 47%
  • Streptococcus pyogenes 46%
  314 Nedladdningar (Pure)

• Structure, specificity, and mode of interaction for bacterial albumin-binding modules.

  Johansson, M. U., Frick, I-M., Nilsson, H., Kraulis, P. J., Hober, S., Jonasson, P., Linhult, M., Nygren, P-A., Uhlén, M., Björck, L., Drakenberg, T., Forsén, S. & Wikström, M., 2002, I: Journal of Biological Chemistry. 277, 10, s. 8114-8120

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Albumins 100%
  • Protein 48%
  • Streptococcus 47%
  • Solution Structure 40%
  • Carrier Proteins 39%

• Uptake and intracellular transportation of a bacterial surface protein in lymphoid cells.

  Frick, I-M., Axcrona, K., Härdig, Y., Tapper, H., Gustafsson, L., Kellner, R., Leanderson, T. & Björck, L., 2002, I: Molecular Microbiology. 44, 4, s. 917-934

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Bacterial Proteins 100%
  • Membrane Proteins 67%
  • nucleophosmin 61%
  • Lymphocytes 56%
  • Heterogeneous-Nuclear Ribonucleoprotein Group A-B 35%
• 2001

  Dermatan sulphate is released by proteinases of common pathogenic bacteria and inactivates antibacterial alpha-defensin

  Schmidtchen, A., Frick, I-M. & Björck, L., 2001, I: Molecular Microbiology. 39, 3, s. 708-713

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • alpha-Defensins 100%
  • Dermatan Sulfate 90%
  • Peptide Hydrolases 54%
  • Bacteria 43%
  • dermatan sulfate proteoglycan 35%
• 2000

  Virulent aggregates of Streptococcus pyogenes are generated by homophilic protein-protein interactions

  Frick, I-M., Mörgelin, M. & Björck, L., 2000, I: Molecular Microbiology. 37, 5, s. 1232-1247

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Streptococcus pyogenes 100%
  • Virulence 35%
  • Membrane Proteins 33%
  • Proteins 30%
  • Bacteria 27%
• 1999

  Five homologous repeats of the protein G-related protein MIG cooperate in binding to goat immunoglobulin G

  Vasi, J., Svensson, J., Frick, I-M. & Muller, H. P., 1999, I: Infection and Immunity. 67, 1, s. 413-416

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • immunoglobulin G 100%
  • Goats 92%
  • goats 68%
  • Immunoglobulin G 63%
  • Streptococcus dysgalactiae 31%
• 1998

  Helicobacter pylori adhesin binding fucosylated histo-blood group antigens revealed by retagging

  Ilver, D., Arnqvist, A., Ogren, J., Frick, I-M., Kersulyte, D., Incecik, E. T., Berg, D. E., Covacci, A., Engstrand, L. & Boren, T., 1998, I: Science. 279, 5349, s. 373-377

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Antigen 100%
  • Strain 82%

• Size-selectivity of the glomerular barrier to high molecular weight proteins: upper size limitations of shunt pathways

  Tencer, J., Frick, I-M., Öquist, B. W., Alm, P. & Rippe, B., 1998, I: Kidney International. 53, 3, s. 709-715

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Molecular Weight 100%
  • Puromycin Aminonucleoside 91%
  • Pregnancy-Associated alpha 2-Macroglobulins 86%
  • Urine 63%
  • Proteins 44%
• 1995

  Protein H--a bacterial surface protein with affinity for both immunoglobulin and fibronectin type III domains

  Frick, I-M., Crossin, K. L., Edelman, G. M. & Björck, L., 1995, I: EMBO Journal. 14, 8, s. 1674-1679

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Fibronectin Type III Domain 100%
  • Bacterial Proteins 76%
  • Fibronectin 75%
  • Neural Cell Adhesion Molecules 57%
  • Immunoglobulins 55%

• Structure and stability of protein H and the M1 protein from Streptococcus pyogenes. Implications for other surface proteins of gram-positive bacteria

  Nilson, B., Frick, I-M., Åkesson, P., Forsén, S., Björck, L., Åkerström, B. & Wikström, M., 1995, I: Biochemistry. 34, 41, s. 13688-13698

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Streptococcus pyogenes 100%
  • Protein Stability 96%
  • Gram-Positive Bacteria 89%
  • Membrane Proteins 67%
  • Protein 33%
• 1994

  Protein H--a surface protein of Streptococcus pyogenes with separate binding sites for IgG and albumin

  Frick, I-M., Åkesson, P., Cooney, J., Sjöbring, U., Schmidt, K-H., Gomi, H., Hattori, S., Tagawa, C., Kishimoto, F. & Björck, L., 1994, I: Molecular Microbiology. 12, 1, s. 143-151

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Streptococcus pyogenes 100%
  • Albumins 70%
  • Membrane Proteins 67%
  • Binding Sites 62%
  • Immunoglobulin G 61%