Karin Olsson

2023

Enhanced protein synthesis is a defining requirement for neonatal B cell development

Åkerstrand, H., Boldrin, E., Montano, G., Vanhee, S., Olsson, K., Krausse, N., Vergani, S., Ciesla, M., Bellodi, C. & Yuan, J., 2023, I: Frontiers in Immunology.

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2019

Lin28b controls a neonatal to adult switch in B cell positive selection

Vanhee, S., Åkerstrand, H., Kristiansen, T. A., Datta, S., Montano, G., Vergani, S., Lang, S., Ungerbäck, J., Doyle, A., Olsson, K., Beneventi, G., Jensen, C. T., Bellodi, C., Soneji, S., Sigvardsson, M., Gyllenbäck, E. J. & Yuan, J., 2019, I: Science Immunology. 4, 39, eaax4453.

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171 Nedladdningar (Pure)

2015

Disruption of the 5S RNP-Mdm2 interaction significantly improves the erythroid defect in a mouse model for Diamond-Blackfan anemia.

Jaako, P., Debnath, S., Olsson, K., Zhang, Y., Flygare, J., Lindström, M. S., Bryder, D. & Karlsson, S., 2015, I: Leukemia. 29, 11, s. 2221-2229

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247 Nedladdningar (Pure)

Lentiviral gene therapy using cellular promoters cures type 1 Gaucher disease in mice.

Dahl, M., Doyle, A., Olsson, K., Månsson, J.-E., Marques, A. R. A., Mirzaian, M., Aerts, J. M., Ehinger, M., Rothe, M., Modlich, U., Schambach, A. & Karlsson, S., 2015, I: Molecular Therapy. 23, 5, s. 835-844

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2014

Gene therapy cures the anemia and lethal bone marrow failure in mouse model for RPS19-deficient Diamond-Blackfan anemia.

Jaako, P., Debnath, S., Olsson, K., Modlich, U., Rothe, M., Schambach, A., Flygare, J. & Karlsson, S., 2014, I: Haematologica. 99, 12, s. 1792-1798 7 s.

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2012

Dietary L-leucine improves the anemia in a mouse model for Diamond-Blackfan anemia.

Jaako, P., Debnath, S., Olsson, K., Bryder, D., Flygare, J. & Karlsson, S., 2012, I: Blood. 120, 11, s. 2225-2228

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2011

High levels of the adhesion molecule CD44 on leukemic cells generate acute myeloid leukemia relapse after withdrawal of the initial transforming event.

Quere, R., Andradottir, S., Brun, A., Zubarev, R. A., Karlsson, G., Olsson, K., Magnusson, M., Cammenga, J. & Karlsson, S., 2011, I: Leukemia. 25, s. 515-526

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Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.

Jaako, P., Flygare, J., Olsson, K., Quere, R., Ehinger, M., Henson, A., Ellis, S., Schambach, A., Baum, C., Richter, J., Larsson, J., Bryder, D. & Karlsson, S., 2011, I: Blood. 118, s. 6087-6096

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2010

Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture.

Singbrant, S., Karlsson, G., Ehinger, M., Olsson, K., Jaako, P., Miharada, K., Stadtfeld, M., Graf, T. & Karlsson, S., 2010, I: Blood. 115, s. 4689-4698

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Chronic RPS19 Deficiency Leads to Bone Marrow Failure In a Mouse Model for Diamond Blackfan Anemia

Jaako, P., Flygare, J., Olsson, K., Quere, R., Larsson, J., Bryder, D. & Karlsson, S., 2010, I: Blood. 116, 21, s. 89-89

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High Levels of the Adhesion Molecule CD44 on Leukemic Cells Generate Acute Myeloid Leukemia Relapse After Withdrawal of the Initial Transforming Event

Quere, R., Andradottir, S., Brun, A., Zubarev, R., Karlsson, G., Olsson, K., Magnusson, M., Cammenga, J. & Karlsson, S., 2010, I: Blood. 116, 21, s. 1298-1298

Forskningsoutput: Tidskriftsbidrag › Publicerat konferensabstract › Peer review

2009

A Novel Mouse Model for RPS19-Deficient Diamond-Blackfan Anemia Locates the Erythroid Defect at CFU-E/Proerythroblast Transition

Jaako, P., Flygare, J., Olsson, K., Schambach, A., Baum, C., Larsson, J., Bryder, D. & Karlsson, S., 2009, I: Blood. 114, 22, s. 79-79

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In an inducible model of acute myeloid leukemia, secondary hits are required to generate a leukemia relapse after removal of the initial transforming event

Quere, R., Andradottir, S., Brun, A., Karlsson, G., Magnusson, M., Olsson, K., Rissler, M. & Karlsson, S., 2009, I: Experimental Hematology. 37, 9, s. S16-S16

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2008

Gene therapy of Diamond Blackfan anemia CD34(+) cells leads to improved erythroid development and engraftment following transplantation.

Flygare, J., Olsson, K., Richter, J. & Karlsson, S., 2008, I: Experimental Hematology. 36, s. 1428-1435

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Smad4 as a Therapeutic Target in Nup98-HoxA9-Induced Leukemia.

Quere, R., Karlsson, G., Andradottir, S., Rissler, M., Olsson, K., Hertwig, F., Reckzeh, K., Cammenga, J. & Karlsson, S., 2008, I: Blood. 112, 11, s. 635-635

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2006

Effective cell and gene therapy in a murine model of Gaucher disease.

Berglin-Enquist, I., Nilsson, E. C., Ooka, A., Mansson, J.-E., Olsson, K., Ehinger, M., Brady, R. O., Richter, J. & Karlsson, S., 2006, I: Proceedings of the National Academy of Sciences. 103, 37, s. 13819-13824

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2005

Gene Transfer to Repopulating Human CD34(+) Cells Using Amphotropic-, GALV-, or RD114-Pseudotyped HIV-1-Based Vectors from Stable Producer Cells.

Relander, T., Askmyr, M., Olsson, K., Ikeda, Y., Takeuchi, Y., Collins, M. & Richter, J., 2005, I: Molecular Therapy. 11, 3, s. 452-459

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2003

Efficient characterization of retro-, lenti-, and foamyvector-transduced cell populations by high-accuracy insertion site sequencing

Schmidt, M., Glimm, H., Wissler, M., Hoffmann, G., Olsson, K., Sellers, S., Carbonaro, D., Tisdale, J., Leurs, C., Hanenberg, H., Dunbar, C., Kiem, H., Karlsson, S., Kohn, D., Williams, D. & von Kalle, C., 2003, Annals of the New York Academy of Sciences (HEMATOPOIETIC STEM CELLS 2002: GENETICS AND FUNCTION: Fourth International Symposium). New York Academy of Sciences, Vol. 996. s. 112-121

Forskningsoutput: Kapitel i bok/rapport/Conference proceeding › Konferenspaper i proceeding › Peer review

Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis.

Woods, N.-B., Muessig, A., Schmidt, M., Flygare, J., Olsson, K., Salmon, P., Trono, D., von Kalle, C. & Karlsson, S., 2003, I: Blood. 101, 4, s. 1284-1289

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2002

Efficient Oncoretroviral Transduction of Extended Long-Term Culture-Initiating Cells and NOD/SCID Repopulating Cells: Enhanced Reconstitution with Gene-Marked Cells Through an Ex Vivo Expansion Approach.

Björgvinsdottir, H., Bryder, D., Sitnicka Quinn, E., Ramsfjell, V., De Jong, I., Olsson, K., Rusterholz, C., Karlsson, S. & Jacobsen, S. E. W., 2002, I: Human Gene Therapy. 13, 9, s. 1061-1073

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Overexpression of Gibbon Ape Leukemia Virus (GALV) Receptor (GLVR1) on Human CD34(+) Cells Increases Gene Transfer Mediated by GALV Pseudotyped Vectors.

Relander, T., Brun, A., Olsson, K., Pedersen, L. & Richter, J., 2002, I: Molecular Therapy. 6, 3, s. 400-406

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2001

Lentiviral-mediated gene transfer into haematopoietic stem cells

Woods, N. B., Mikkola, H., Nilsson, E., Olsson, K., Trono, D. & Karlsson, S., 2001 apr., I: Journal of Internal Medicine. 249, 4, s. 339-343 5 s.

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2000

Lentiviral gene transfer into primary and secondary NOD/SCID repopulating cells

Woods, N. B., Fahlman, C., Mikkola, H., Hamaguchi, I., Olsson, K., Zufferey, R., Jacobsen, S. E., Trono, D. & Karlsson, S., 2000 dec. 1, I: Blood. 96, 12, s. 3725-33

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Karin Olsson

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