Knut Kotarsky

2023

cDC1-derived IL-27 regulates small intestinal CD4+ T cell homeostasis in mice

Ahmadi, F., Junghus, F., Ashworth, C., Lappalainen, A., Mörbe, U., Kotarsky, K. & Agace, W. W., 2023, I: The Journal of experimental medicine. 220, 3

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2022

Identification and characterization of murine glycoprotein 2-expressing intestinal dendritic cells

Luda, K. M., Da Silva, C., Ahmadi, F., Mowat, A. M., Ohno, H., Kotarsky, K. & Agace, W. W., 2022 nov., I: Scandinavian Journal of Immunology. 96, 5, s. 1-12 e13219.

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IRF8 deficiency induces the transcriptional, functional, and epigenetic reprogramming of cDC1 into the cDC2 lineage

Lança, T., Ungerbäck, J., Da Silva, C., Joeris, T., Ahmadi, F., Vandamme, J., Svensson-Frej, M., Mowat, A. M., Kotarsky, K., Sigvardsson, M. & Agace, W. W., 2022 aug. 9, I: Immunity. 55, 8, s. 1431-1447.e11

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A self-sustaining layer of early-life-origin B cells drives steady-state IgA responses in the adult gut

Vergani, S., Muleta, K. G., Da Silva, C., Doyle, A., Kristiansen, T. A., Sodini, S., Krausse, N., Montano, G., Kotarsky, K., Nakawesi, J., Åkerstrand, H., Vanhee, S., Gupta, S. L., Bryder, D., Agace, W. W., Lahl, K. & Yuan, J., 2022, I: Immunity. 55, 10, s. 1829-1842.e6

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2021

Intestinal cDC1 drive cross-tolerance to epithelial-derived antigen via induction of FoxP3+CD8+ Tregs

Joeris, T., Gomez-Casado, C., Holmkvist, P., Tavernier, S. J., Silva-Sanchez, A., Klotz, L., Randall, T. D., Mowat, A. M., Kotarsky, K., Malissen, B. & Agace, W. W., 2021 juni, I: Science Immunology. 6, 60, eabd3774.

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2020

Migration of murine intestinal dendritic cell subsets upon intrinsic and extrinsic TLR3 stimulation

López, A. G., Bekiaris, V., Luda, K. M., Hütter, J., Ulmert, I., Getachew Muleta, K., Nakawesi, J., Kotarsky, K., Malissen, B., O'Keeffe, M., Holzmann, B., Agace, W. & Lahl, K., 2020 okt., I: European Journal of Immunology. 50, 10, s. 1525-1536 12 s.

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2018

Retinoic acid signaling in thymic epithelial cells regulates thymopoiesis

Wendland, K., Niss, K., Kotarsky, K., Wu, N. Y. H., White, A. J., Jendholm, J., Rivollier, A., Izarzugaza, J. M. G., Brunak, S., Holländer, G. A., Anderson, G., Sitnik, K. M. & Agace, W. W., 2018 juli 15, I: Journal of Immunology. 201, 2, s. 524-532 9 s.

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2016

IRF8 Transcription-Factor-Dependent Classical Dendritic Cells Are Essential for Intestinal T Cell Homeostasis

Luda, K. M., Joeris, T., Persson, E. K., Rivollier, A., Demiri, M., Sitnik, K. M., Pool, L., Holm, J. B., Melo-Gonzalez, F., Richter, L., Lambrecht, B. N., Kristiansen, K., Travis, M. A., Svensson-Frej, M., Kotarsky, K. & Agace, W. W., 2016 apr. 19, I: Immunity. 44, 4, s. 860-874 15 s.

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Context-Dependent Development of Lymphoid Stroma from Adult CD34(+) Adventitial Progenitors.

Sitnik, K. M., Wendland, K., Weishaupt, H., Uronen-Hansson, H., White, A. J., Anderson, G., Kotarsky, K. & Agace, W. W., 2016, I: Cell Reports. 14, 10, s. 2375-2388

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2015

CCR2(+)CD103(-) intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells.

Scott, C. L., Bain, C. C., Wright, P. B., Sichien, D., Kotarsky, K., Persson, E., Luda, K., Guilliams, M., Lambrecht, B. N., Agace, W., Milling, S. W. & Mowat, A., 2015, I: Mucosal Immunology. 8, 2, s. 327-339

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2013

IRF4 Transcription-Factor-Dependent CD103(+)CD11b(+) Dendritic Cells Drive Mucosal T Helper 17 Cell Differentiation.

Persson, E., Uronen-Hansson, H., Semmrich, M., Rivollier, A., Hägerbrand, K., Marsal, J., Gudjonsson, S., Håkansson, U., Reizis, B., Kotarsky, K. & Agace, W., 2013, I: Immunity. 38, 5, s. 958-969

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

2012

Mesenchymal Cells Regulate Retinoic Acid Receptor-Dependent Cortical Thymic Epithelial Cell Homeostasis.

Sitnik, K. M., Kotarsky, K., White, A. J., Jenkinson, W. E., Anderson, G. & Agace, W., 2012, I: Journal of immunology. 188, 10, s. 4801-4809

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

2011

Bile retinoids imprint intestinal CD103(+) dendritic cells with the ability to generate gut-tropic T cells.

Jaensson Gyllenbäck, E., Kotarsky, K., Zapata, F., Persson, E. K., Gundersen, T. E., Blomhoff, R. & Agace, W., 2011, I: Mucosal Immunology. 4, s. 438-447

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

2010

A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.

Kotarsky, K., Sitnik, K., Stenstad, H., Kotarsky, H., Schmidtchen, A., Koslowski, M., Wehkamp, J. & Agace, W., 2010, I: Mucosal Immunology. 3, s. 40-48

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2009

Expression of Alkaline Sphingomyelinase in Yeast Cells and Anti-inflammatory Effects of the Expressed Enzyme in a Rat Colitis Model.

Andersson, D., Kotarsky, K., Wu, J., Agace, W. & Duan, R-D., 2009, I: Digestive Diseases and Sciences. 2008, Nov 7, s. 1440-1448

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

2007

Differential homing mechanisms regulate regionalized effector CD8 alpha beta(+) T cell accumulation within the small intestine

Stenstad, H., Svensson Frej, M., Cucak, H., Kotarsky, K. & Agace, W., 2007, I: Proceedings of the National Academy of Sciences. 104, 24, s. 10122-10127

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2006

Expression of recombinant protein in CHO and HeLa cells and its follow-up using EGF reporter gene

Hendrick, V., Ribeiro de Sousa, D., dos Santos Pedregal, A. R., Bassens, C., Rigaux, P., Sato, K., Kotarsky, K. & Werenne, J., 2006, Animal Cell Technology: Basic and Applied Aspects. Springer, s. 55-59

Forskningsoutput: Kapitel i bok/rapport/Conference proceeding › Konferenspaper i proceeding › Peer review

Functional characterization of the CCL25 promoter in small intestinal epithelial cells suggests a regulatory role for caudal-related homeobox (Cdx) transcription factors

Ericsson, A., Kotarsky, K., Svensson Frej, M., Sigvardsson, M. & Agace, W., 2006, I: Journal of Immunology. 176, 6, s. 3642-3651

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Lysophosphatidic Acid Binds to and Activates GPR92, a G Protein-Coupled Receptor Highly Expressed in Gastrointestinal Lymphocytes

Kotarsky, K., Boketoft, A., Bristulf, J., Nilsson, N., Norberg, A., Hansson, S., Sillard, R., Owman, C., Leeb-Lundberg, F. & Olde, B., 2006, I: Journal of Pharmacology and Experimental Therapeutics. 318, 2, s. 619-628

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2005

Sodium Butyrate Enhancement of Protein Expression

Bassens, C., Rigaux, P., Hendrick, V., Cherlet, M., Sato, K., Kotarsky, K. & Werenne, J., 2005, Animal Cell Technology Meets Genomics. Springer, Vol. 2. s. 625-627

Forskningsoutput: Kapitel i bok/rapport/Conference proceeding › Kapitel samlingsverk › Forskning

2004

Developments toward a Microfluidic System for Long-Term Monitoring of Dynamic Cellular Events in Immobilized Human Cells.

Davidsson, R., Boketoft, Å., Bristulf, J., Kotarsky, K., Olde, B., Owman, C., Bengtsson, M., Laurell, T. & Emnéus, J., 2004, I: Analytical Chemistry. 76, 16, s. 4715-4720

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Expression of Recombinant Protein in CHO and HELA cells and its follow-up using EGF reporter gene

Hendrick, V., Ribeiro de Sousa, D., dos Santos, A. R., Bassens, A. R., Rigaux, C., Sato, P., Kotarsky, K. & Werenne, J., 2004, Animal Cell Technology: Basic & Applied Aspects. Iijima, S. & Nishijima, K. (red.). Springer, Vol. 14. s. 55-60 6 s.

Forskningsoutput: Kapitel i bok/rapport/Conference proceeding › Konferenspaper i proceeding › Peer review

Reverse pharmacology and the de-orphanization of 7TM receptors

Kotarsky, K. & Nilsson, N. E., 2004, I: Drug Discovery Today: Technologies. 2, 1, s. 99-104

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2003

A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs.

Kotarsky, K., Nilsson, N., Flodgren, E., Owman, C. & Olde, B., 2003, I: Biochemical and Biophysical Research Communications. 301, 2, s. 406-410

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Development of sensitive cellular assay systems and their application to the identification of "orphan" seven-transmembrane receptors

Kotarsky, K., 2003, Knut Kotarsky; Tordmulevägen 3c; 22735 LUND Sweden,. 96 s.

Forskningsoutput: Avhandling › Doktorsavhandling (sammanläggning)

Fil

163 Nedladdningar (Pure)

Differential inhibition of receptor activation by two mouse monoclonal antibodies specific for the human leukotriene B(4) receptor, BLT(1).

Sabirsh, A., Pettersson, A., Boketoft, Å., Kotarsky, K. & Owman, C., 2003, I: International Immunopharmacology. 3, 13-14, s. 1829-1839

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Identification of a free fatty acid receptor, FFA(2)R, expressed on leukocytes and activated by short-chain fatty acids.

Nilsson, N., Kotarsky, K., Owman, C. & Olde, B., 2003, I: Biochemical and Biophysical Research Communications. 303, 4, s. 1047-1052

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Optimized reporter gene assays based on a synthetic multifunctional promoter and a secreted luciferase.

Kotarsky, K., Antonsson, L., Owman, C. & Olde, B., 2003, I: Analytical Biochemistry. 316, 2, s. 208-215

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Progress in methodology improved reporter gene assays used to identify ligands acting on orphan seven-transmembrane receptors.

Kotarsky, K., Nilsson, N., Olde, B. & Owman, C., 2003, I: Pharmacology and Toxicology. 93, 6, s. 249-258

Forskningsoutput: Tidskriftsbidrag › Översiktsartikel › Peer review

Fil

233 Nedladdningar (Pure)

2002

Monitoring of human chemiluminescent reporter cell lines expressing G-protein-coupled receptors in a microfluidic system

Davidsson, R., Bristulf, J., Kotarsky, K., Olde, B., Owman, C., Bengtsson, M., Laurell, T. & Emnéus, J., 2002, Micro total analysis systems 2002. Baba, Y., Shoji, S. & van den Berg, A. (red.). Springer, Vol. 2. s. 811-813 3 s.

Forskningsoutput: Kapitel i bok/rapport/Conference proceeding › Konferenspaper i proceeding › Peer review

2001

A chimeric reporter gene allowing for clone selection and high-throughput screening of reporter cell lines expressing G-protein-coupled receptors

Kotarsky, K., Owman, C. & Olde, B., 2001, I: Analytical Biochemistry. 288, 2, s. 209-215

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Chronic ethanol exposure enhances activating protein-1 transcriptional activity in human neuroblastoma cells

Fried, U., Kotarsky, K. & Alling, C., 2001, I: Alcohol. 24, 3, s. 189-195

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2000

Cloning and characterization of cDNA encoding a novel human leukotriene B(4) receptor

Tryselius, Y., Nilsson, N., Kotarsky, K., Olde, B. & Owman, C., 2000, I: Biochemical and Biophysical Research Communications. 274, 2, s. 377-382

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First-generation monoclonal antibodies identifying the human leukotriene B(4) receptor-1

Pettersson, A., Boketoft, Å., Sabirsh, A., Nilsson, N., Kotarsky, K., Olde, B. & Owman, C., 2000, I: Biochemical and Biophysical Research Communications. 279, 2, s. 520-525

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

Knut Kotarsky

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