Forskningsoutput per år
Forskningsoutput per år
Universitetslektor, Gruppledare, Translational Oncogenomics Unit
We focus on translating innovative cancer genomics, liquid biopsies, and insights on PTEN/PI3K/AKT signaling in to new clinical applications. We and others have previously shown the PTEN/PI3K/AKT pathway to be a key promotor of cancer and to be a target for therapeutic modulation. With a particular interest in this pathway, we are applying recent advances in genome-wide technologies to study breast cancer biology with the goal of translating our findings into new clinical applications. We are also investigating the clinical utility of monitoring circulating tumor DNA (ctDNA) in cancer patients. Specifically, we aim to:
Our research is facilitated by close cooperation with fellow research units of the Canceromics Branch and Division of Oncology and Pathology, collaborations internationally, partnership with clinical oncologists, surgeons, and pathologists, and participation as one of the principal investigators of the Sweden Canceromics Analysis Network - Breast (SCAN-B) Initiative.
Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
Forskningsoutput: Tidskriftsbidrag › Publicerat konferensabstract
Brueffer, C., Saal, L., Höglund, M. & Axelson, H.
2014/06/01 → 2021/01/13
Projekt: Avhandling