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Personlig profil

Forskning

Philipp Kaldis is a professor in “Metabolic disorders and liver disease” at the Department of Clinical Sciences and a vice-coordinator of the Lund University Diabetes Centre (LUDC), where he contributes to the leadership of the centre.

He also serves as Special Chief Editor for the Cell Growth and Division section at “Frontiers in Cell and Developmental Biology” and as Editor-in-Chief for the journal “Cell Division” (BioMed Central/Springer/Nature).

Philipp received his PhD from the ETH Zürich (Switzerland), did his postdoc at Yale University School of Medicine (USA), and started his own laboratory at the National Cancer Institute (NIH, USA). After being promoted to Senior Investigator, he moved to Singapore where he worked at the Institute of Molecular Cell Biology (IMCB/A*STAR/National University of Singapore). In 2019, Philipp returned to Europe to join Lund University.

Philipp was trained as a hard-core biochemist and in his own lab uses extensively genetically modified mice to study cell cycle regulation and human disease. In the last decade, his laboratory has focused on the liver, liver regeneration, liver cancer, and metabolism. We are currently studying changes in metabolism, especially in the context of fatty liver disease (NAFLD) and diabetes. We use cell biology, genetics, metabolomics, lipidomics, and genomics to determine the mechanisms causing these diseases. These large dataset allow us to identify pathways that are deregulated and to do mechanistic studies. Our work will help to provide a better understanding of liver disease & diabetes and open new avenues for therapeutic approaches.

Ämnesklassifikation (UKÄ)

  • Cell- och molekylärbiologi
  • Biokemi och molekylärbiologi
  • Cellbiologi
  • Fysiologi
  • Cancer och onkologi
  • Gastroenterologi

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