Pontus Dunér

Sökresultat

• 2024

  Dysregulation of MMP2-dependent TGF-ß2 activation impairs fibrous cap formation in type 2 diabetes-associated atherosclerosis

  Singh, P., Sun, J., Cavalera, M., Al-Sharify, D., Matthes, F., Barghouth, M., Tengryd, C., Dunér, P., Persson, A., Sundius, L., Nitulescu, M., Bengtsson, E., Rattik, S., Engelbertsen, D., Orho-Melander, M., Nilsson, J., Monaco, C., Goncalves, I. & Edsfeldt, A., 2024 dec., I: Nature Communications. 15, s. 1-18 10464.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Atherosclerosis 100%
  • Maturity Onset Diabetes of the Young 100%
  • Capping Phenomenon 100%
  • Fibrous Cap 100%
  • Gelatinase A 100%

• A New IL-6-Inducing Mechanism in Cancer with New Therapeutic Possibilities

  Håkansson, L., Dunér, P., Broströmer, E., Gustavsson, B., Wettergren, Y., Ghafouri, B., Håkansson, A. & Clinchy, B., 2024 nov., I: Cancers. 16, 21, 3588.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Interleukin 6 100%
  • Albumin 23%
  • Peptides 15%
  • Inflammatory Disorder 7%
  • Blood Level 7%

• Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis

  Chen, Y., Gialeli, C., Shen, J., Dunér, P., Walse, B., Duelli, A., Caing-Carlsson, R., Blom, A. M., Zibert, J. R., Nilsson, A. H., Alenfall, J., Liang, C. & Nilsson, J., 2024 juni 11, I: Pharmacological Research. 205, 18 s., 107259.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Angiogenesis 100%
  • Peptide 100%
  • Osteopontin 100%
  • Vasculotropin 100%
  • Phosphorylation 50%
• 2023

  Transforming growth factor-β2 is associated with atherosclerotic plaque stability and lower risk for cardiovascular events

  Edsfeldt, A., Singh, P., Matthes, F., Tengryd, C., Cavalera, M., Bengtsson, E., Dunér, P., Volkov, P., Karadimou, G., Gisterå, A., Orho-Melander, M., Nilsson, J., Sun, J. & Gonçalves, I., 2023 aug., I: Cardiovascular Research. 119, 11, s. 2061-2073

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Transforming Growth Factor 100%
  • TGF Beta 2 100%
  • Plaque 100%
  • Cardiovascular System 100%
  • Isoform 55%

• Ablation of GPR56 Causes β-Cell Dysfunction by ATP Loss through Mistargeting of Mitochondrial VDAC1 to the Plasma Membrane

  Mohammad Al-Amily, I., Sjögren, M., Duner, P., Tariq, M., Wollheim, C. B. & Salehi, A., 2023, I: Biomolecules. 13, 3, 557.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Cell Membrane 100%
  • Voltage-Dependent Anion Channel 100%
  • Electric Potential 100%
  • Voltage Dependent Anion Channel 1 100%
  • Collagen 50%
• 2021

  Antibodies against apoB100 peptide 210 inhibit atherosclerosis in apoE^-/- mice

  Dunér, P., Mattisson, I. Y., Fogelstrand, P., Glise, L., Ruiz, S., Farina, C., Borén, J., Nilsson, J. & Bengtsson, E., 2021 dec. 1, I: Scientific Reports. 11, 1, 9022.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Peptide 100%
  • Apolipoprotein B 100%
  • Human 25%
  • Protein 25%
  • Reduction (Chemistry) 25%
• 2020

  The proteoglycan mimecan is associated with carotid plaque vulnerability and increased risk of future cardiovascular death

  Tengryd, C., Nielsen, S. H., Cavalera, M., Bengtsson, E., Genovese, F., Karsdal, M., Dunér, P., Orho-Melander, M., Nilsson, J., Edsfeldt, A. & Gonçalves, I., 2020 nov., I: Atherosclerosis. 313, s. 88-95 8 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Plaque 100%
  • Death 100%
  • Cardiovascular System 100%
  • Proteoglycan 100%
  • Macrophage 36%

• An osteopontin-derived peptide inhibits human hair growth at least in part by decreasing fibroblast growth factor-7 production in outer root sheath keratinocytes

  Alam, M., Bertolini, M., Gherardini, J., Keren, A., Ponce, L., Chéret, J., Alenfall, J., Dunér, P., Hultgårdh, A., Gilhar, A. & Paus, R., 2020 juni, I: British Journal of Dermatology. 182, 6, s. 1404-1414 11 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Keratinocyte Growth Factor 100%
  • Hypertrichosis 42%
  • Therapeutic Procedure 40%
  • Hair Follicle 40%
  • Stem Cell 28%

• Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin

  Herum, K. M., Romaine, A., Wang, A., Melleby, A. O., Strand, M. E., Pacheco, J., Braathen, B., Dunér, P., Tønnessen, T., Lunde, I. G., Sjaastad, I., Brakebusch, C., McCulloch, A. D., Gomez, M. F., Carlson, C. R. & Christensen, G., 2020 feb. 4, I: Journal of the American Heart Association. 9, 3, s. e013518

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Thrombin 100%
  • Syndecan 4 100%
  • Mouse 25%
  • Collagen 13%
  • Pressure 13%

• Inhibitory effect of UDP-glucose on cAMP generation and insulin secretion

  Parandeh, F., Amisten, S., Verma, G., Mohammed Al-Amily, I., Dunér, P. & Salehi, A., 2020, I: The Journal of biological chemistry. 295, 45, s. 15245-15252 8 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Glucose 100%
  • Insulin Secretion 100%
  • Cyclic Adenosine Monophosphate 100%
  • Insulin 100%
  • Non Insulin Dependent Diabetes Mellitus 25%

• Orphan G-protein coupled receptor 183 (GPR183) potentiates insulin secretion and prevents glucotoxicity-induced β-cell dysfunction

  Taneera, J., Mohammed, I., Mohammed, A. K., Hachim, M., Dhaiban, S., Malek, A., Dunér, P., Elemam, N. M., Sulaiman, N., Hamad, M. & Salehi, A., 2020, I: Molecular and Cellular Endocrinology. 499, 110592.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • NeuroD 100%
• 2019

  ILC2 transfers to apolipoprotein E deficient mice reduce the lipid content of atherosclerotic lesions

  Mantani, P. T., Dunér, P., Ljungcrantz, I., Nilsson, J., Björkbacka, H. & Fredrikson, G. N., 2019 dec. 10, I: BMC Immunology. 20, 47.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Lipid 100%
  • Lesion 100%
  • Mouse 100%
  • In Vitro 80%
  • Killer Cell 60%

• Activation of immune responses against the basement membrane component collagen type IV does not affect the development of atherosclerosis in ApoE-deficient mice

  Vallejo, J., Dunér, P., To, F., Engelbertsen, D., Gonçalves, I., Nilsson, J. & Bengtsson, E., 2019 apr. 12, I: Scientific Reports. 9, 1, 5964.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Immune Response 100%
  • Basement Membrane 100%
  • Membrane Component 100%
  • Type IV Collagen 100%
  • Activation of Immune Response 100%

• Associations of Interleukin-5 With Plaque Development and Cardiovascular Events

  Knutsson, A., Björkbacka, H., Dunér, P., Engström, G., Binder, C. J., Nilsson, A. H. & Nilsson, J., 2019, I: JACC: Basic to Translational Science. 4, 8, s. 891-902 12 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Plaque 100%
  • Cardiovascular System 100%
  • Apoplexy 16%
  • Follow up 16%
  • Stimulation 16%

• Cartilage Oligomeric Matrix Protein Associates With a Vulnerable Plaque Phenotype in Human Atherosclerotic Plaques

  Hultman, K., Edsfeldt, A., Björkbacka, H., Dunér, P., Sundius, L., Nitulescu, M., Persson, A., Boyle, J. J., Nilsson, J., Hultgårdh-Nilsson, A., Bengtsson, E. & Gonçalves, I., 2019, I: Stroke. 50, 11, s. 3289-3292 4 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Vulnerable Plaque 100%
  • Association 100%
  • Plaque 41%
  • Cells 25%
  • Disease 16%

• The functional impact of G protein-coupled receptor 142 (Gpr142) on pancreatic β-cell in rodent

  Al-Amily, I. M., Dunér, P., Groop, L. & Salehi, A., 2019, I: Pflügers Archiv. 471, 4, s. 633-645

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Cells 100%
  • G Protein Coupled Receptor 100%
  • Rodent 100%
  • Insulin 35%
  • Glucose 23%
• 2018

  Hyperglycemia does not affect tissue repair responses in shear stress-induced atherosclerotic plaques in ApoE-/-mice

  Hsiung, S., Knutsson, A., Vallejo, J., Dunér, P., Heinonen, S. E., Jönsson-Rylander, A. C., Bengtsson, E., Nilsson, J. & Hultgårdh-Nilsson, A., 2018 dec. 1, I: Scientific Reports. 8, 1, 7530.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Hyperglycemia 100%
  • Shear Stress 100%
  • Diabetes 50%
  • Plaque 50%
  • Smooth Muscle Cell 50%

• Activation of imidazoline receptor I₂, and improved pancreatic β-cell function in human islets

  Amisten, S., Duner, P., Asplund, O., Mohammed Al-Amily, I., Groop, L. & Salehi, A., 2018 sep., I: Journal of Diabetes and its Complications. 32, 9, s. 813-818

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Glucose 100%
  • Cyclic Adenosine Monophosphate 100%
  • Insulin 100%
  • Real-Time Polymerase Chain Reaction 66%
  • RNA-Sequencing 50%

• Interleukin-25 (IL-25) has a protective role in atherosclerosis development in the aortic arch in mice

  Mantani, P. T., Dunér, P., Bengtsson, E., Ljungcrantz, I., Sundius, L., To, F., Nilsson, J., Björkbacka, H. & Fredrikson, G. N., 2018 jan. 1, I: Journal of Biological Chemistry. 293, 18, s. 6791-6801 11 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Mouse 100%
  • Spleen 20%
  • Th1 Cell 20%
  • Inflammation 10%
  • Blocking Antibody 10%
• 2017

  ADAMTS-7 is associated with a high-risk plaque phenotype in human atherosclerosis

  Bengtsson, E., Hultman, K., Dunér, P., Asciutto, G., Almgren, P., Orho-Melander, M., Melander, O., Nilsson, J., Hultgårdh, A. & Gonçalves, I., 2017 dec. 1, I: Scientific Reports. 7, 1, 3753.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Atherosclerosis 100%
  • Plaque 100%
  • Staining Technique 100%
  • Immunohistochemistry 100%
  • Patient 60%

• Autoantibodies against aldehyde-modified collagen type IV are associated with risk of development of myocardial infarction

  Vallejo, J., Dunér, P., Fredrikson, G. N., Nilsson, J. & Bengtsson, E., 2017 dec., I: Journal of Internal Medicine. 282, 6, s. 496-507

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Myocardial Infarction 100%
  • Type IV Collagen 100%
  • Immune Response 22%
  • Alpha Oxidation 22%
  • Patient 11%

• β-Sarcoglycan Deficiency Reduces Atherosclerotic Plaque Development in ApoE-Null Mice

  Murugesan, V., Degerman, E., Knutsson, A., Dunér, P., Holmén-Pålbrink, A.-K., Hultgårdh, A. & Rauch, U., 2017 juli 29, I: Journal of Vascular Research. 54, s. 235-245

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Mouse 100%
  • Smooth Muscle Cell 100%
  • Sarcoglycan 100%
  • Blood Plasma 50%
  • Tumor Necrosis Factor 50%
• 2016

  Adhesion G protein-coupled receptor G1 (ADGRG1/GPR56) and pancreatic β-cell function

  Dunér, P., Mohammed, I., Soni, A., Asplund, O., Safi, F., Storm, P., Groop, L., Amisten, S. & Salehi, S. A., 2016 dec. 1, I: Journal of Clinical Endocrinology and Metabolism. 101, 12, s. 4637-4645 9 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • G Protein Coupled Receptor 100%
  • Cells 16%
  • RNA Sequence 11%
  • Pancreatic Islet 11%
  • Programmed Cell Death 11%

• Glucose-Dependent Insulinotropic Polypeptide (GIP) Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.

  Berglund, L., Lyssenko, V., Ladenvall, C., Kotova, O., Edsfeldt, A., Pilgaard, K., Alkayyali, S., Brøns, C., Forsblom, C., Jonsson, A., Zetterqvist, A., Nitulescu, M., Ruiz McDavitt, C., Dunér, P., Stancáková, A., Kuusisto, J., Ahlqvist, E., Lajer, M., Tarnow, L. & Madsbad, S. & 13 andra, Rossing, P., Kieffer, T. J., Melander, O., Orho-Melander, M., Nilsson, P., Groop, P.-H., Vaag, A., Lindblad, B., Gottsäter, A., Laakso, M., Goncalves, I., Groop, L. & Gomez, M., 2016, I: Diabetes. 65, 1, s. 239-254

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Binding Protein 100%
  • Cyclic Adenosine Monophosphate 100%
  • Osteopontin 100%
  • Response Element 100%
  • Vascularity 100%
  354 Nedladdningar (Pure)

• High levels of cathepsin D and cystatin B are associated with increased risk of coronary events.

  Goncalves, I., Hultman, K., Dunér, P., Edsfeldt, A., Hedblad, B., Nordin Fredrikson, G., Björkbacka, H., Nilsson, J. & Bengtsson, E., 2016, I: Open Heart. 3, 1, s. e000353

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Plaque 100%
  • Rupture 100%
  • Cardiovascular Disease 50%
  • Family 50%
  • Acute Coronary Syndrome 50%

• High Plasma Levels of Galectin-3 Are Associated with Increased Risk for Stroke after Carotid Endarterectomy.

  Edsfeldt, A., Bengtsson, E., Asciutto, G., Dunér, P., Björkbacka, H., Nordin Fredrikson, G., Nilsson, J. & Goncalves, I., 2016, I: Cerebrovascular Diseases. 41, 3-4, s. 199-203

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Galectin-3 100%
  • Stroke 100%
  • Blood Plasma 40%

• Proinflammatory Role of Sphingolipids and Glycosphingolipids in the Human Atherosclerotic Plaque

  Edsfeldt, A., Dunér, P., Ståhlman, M., Mollet, I. G., Asciutto, G., GRUFMAN, A. H. M., Nitulescu, M., Persson, A. F., Fisher, R. M., Melander, O., Orho-Melander, M., Borén, J., Nilsson, J. & Gonçalves, I., 2016, I: Arteriosclerosis, Thrombosis and Vascular Biology. 36, 6, s. 1132-1140

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Inflammation 100%
  • Caspase 100%
  • Smooth Muscle Cell 100%
  • Plaque 100%
  • Inflammation Response 50%
• 2015

  Autoantibodies against basement membrane collagen type IV are associated with myocardial infarction

  McLeod, O., Dunér, P., Samnegård, A., Tornvall, P., Nilsson, J., Hamsten, A. & Bengtsson, E., 2015 mars 1, I: IJC Heart and Vasculature. 6, s. 42-47 6 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Basement Membrane 100%
  • Type IV Collagen 100%
  • Matrix Protein 50%
  • Autoimmune Disease 25%
  • Contrast 25%

• Dystrophin deficiency reduces atherosclerotic plaque development in ApoE-null mice.

  Shami, A., Knutsson, A., Dunér, P., Rauch, U., Bengtsson, E., Tengryd, C., Murugesan, V., Durbeej-Hjalt, M., Goncalves, I., Nilsson, J. & Hultgårdh, A., 2015, I: Scientific Reports. 5, 13904.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Development 100%
  • Shear Stress 57%
  • Plaque 42%
  • Smooth Muscle Cell 42%
  • Carotid Artery 28%

• Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes.

  Goncalves, I., Bengtsson, E., Colhoun, H. M., Shore, A. C., Palombo, C., Natali, A., Edsfeldt, A., Dunér, P., Nordin Fredrikson, G., Björkbacka, H., Östling, G., Aizawa, K., Casanova, F., Persson, M., Gooding, K., Strain, D., Kahn, F., Looker, H. C., Adams, F. & Belch, J. & 6 andra, Pinnoli, S., Venturi, E., Kozakova, M., Gan, L.-M., Schnecke, V. & Nilsson, J., 2015, I: Arteriosclerosis, Thrombosis and Vascular Biology. 35, 7, s. 1723-1731

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Cardiovascular Disease 100%
  • Atherosclerosis 100%
  • Maturity Onset Diabetes of the Young 100%
  • Non Insulin Dependent Diabetes Mellitus 100%
  • Plaque 50%

• High Plasma Levels of Heparin-Binding Epidermal Growth Factor Are Associated With a More Stable Plaque Phenotype and Reduced Incidence of Coronary Events.

  Rattik, S., Wigren, M., Björkbacka, H., Nordin Fredrikson, G., Hedblad, B., Siegbahn, A., Bengtsson, E., Schiopu, A., Edsfeldt, A., Dunér, P., Grufman, H., Goncalves, I. & Nilsson, J., 2015, I: Arteriosclerosis, Thrombosis and Vascular Biology. 35, 1, s. 222-228

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Blood Level 100%
  • Smooth Muscle Cell 100%
  • Plaque 100%
  • Tissue Repair 50%
  • Platelet Derived Growth Factor 50%

• IL-25 Inhibits Atherosclerosis Development in Apolipoprotein E Deficient Mice.

  Mantani, P., Dunér, P., Bengtsson, E., Alm, R., Ljungcrantz, I., Söderberg, I., Sundius, L., To, F., Nilsson, J., Björkbacka, H. & Nordin Fredrikson, G., 2015, I: PLoS ONE. 10, 1, e0117255.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Mouse 100%
  • Immunity 50%
  • Cell Population 50%
  • Inflammatory Disorder 50%
  292 Nedladdningar (Pure)

• Increased aldehyde-modification of collagen type IV in symptomatic plaques - A possible cause of endothelial dysfunction.

  Dunér, P., Goncalves, I., Grufman, H., Edsfeldt, A., To, F., Nitulescu, M., Nilsson, J. & Bengtsson, E., 2015, I: Atherosclerosis. 240, 1, s. 26-32

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Collagen 100%
  • Oxidation Reaction 100%
  • Alpha Oxidation 100%
  • Type IV Collagen 100%
  • Collagens 100%
  246 Nedladdningar (Pure)

• Low elastin content of carotid plaques is associated with increased risk of ipsilateral stroke.

  Asciutto, G., Dias, N., Edsfeldt, A., Nitulescu, M., Persson, A., Nilsson, M. M., Dunér, P., Nilsson, J. & Goncalves, I., 2015, I: PLoS ONE. 10, 3, e0121086.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Stroke 100%
  • Elastin 100%
  177 Nedladdningar (Pure)
• 2014

  Impaired Fibrous Repair: A Possible Contributor to Atherosclerotic Plaque Vulnerability in Patients With Type II Diabetes.

  Edsfeldt, A., Goncalves, I., Grufman, H., Nitulescu, M., Dunér, P., Bengtsson, E., Mollet, I., Persson, A., Nilsson, M. M., Orho-Melander, M., Melander, O., Björkbacka, H. & Nilsson, J., 2014, I: Arteriosclerosis, Thrombosis and Vascular Biology. 34, 9, s. 2143-2150

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Patient with Type 2 Diabetes 100%
  • Inflammation 100%
  • Disease 33%
  • Cardiovascular Disease 33%
  • Plaque 33%

• Plasma S100A8/A9 Correlates With Blood Neutrophil Counts, Traditional Risk Factors, and Cardiovascular Disease in Middle-Aged Healthy Individuals.

  Cotoi, O., Dunér, P., Ko, N., Hedblad, B., Nilsson, J., Björkbacka, H. & Schiopu, A., 2014, I: Arteriosclerosis, Thrombosis and Vascular Biology. 34, 1, s. 202

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Blood Plasma 100%
  • Macrophage 100%
  • Inflammatory Disorder 100%
  • Monocyte 100%
  • Neutrophil Count 100%
  304 Nedladdningar (Pure)
• 2013

  Inhibition of nuclear factor of activated T-cells (NFAT) suppresses accelerated atherosclerosis in diabetic mice.

  Zetterqvist, A., Berglund, L., Blanco, F., Garcia Vaz, E., Wigren, M., Dunér, P., Dutius Andersson, A.-M., To, F., Spégel, P., Nilsson, J., Bengtsson, E. & Gomez, M., 2013, I: PLoS ONE. 8, 6, e65020.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Atherosclerosis 100%
  • Patient 33%
  • Diabetes 33%
  • Protein 33%
  • Apoplexy 33%
  448 Nedladdningar (Pure)
• 2012

  Increased Inflammation in Atherosclerotic Lesions of Diabetic Akita-LDLr(-/-) Mice Compared to Nondiabetic LDLr(-/-) Mice.

  Engelbertsen, D., To, F., Dunér, P., Kotova, O., Söderberg, I., Alm, R., Gomez, M., Nilsson, J. & Bengtsson, E., 2012, I: Experimental Diabetes Research. 2012, Nov.,28, 176162.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Atherosclerosis 100%
  • Lesion 100%
  • Inflammation 100%
  • Diabetes 100%
  • Male 66%
  199 Nedladdningar (Pure)

• Plasma fibronectin deficiency impedes atherosclerosis progression and fibrous cap formation

  Rohwedder, I., Montanez, E., Beckmann, K., Bengtsson, E., Dunér, P., Nilsson, J., Soehnlein, O. & Faessler, R., 2012, I: EMBO Molecular Medicine. 4, 7, s. 564-576

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Capping Phenomenon 100%
  • Fibrous Cap 100%
  • Fibronectin 100%
  • Vascular Occlusion 60%
  • Scleroprotein 20%
• 2011

  Evidence for a role of regulatory T cells in mediating the atheroprotective effect of apolipoprotein B peptide vaccine.

  Wigren, M., Kolbus, D., Dunér, P., Ljungcrantz, I., Söderberg, I., Björkbacka, H., Nordin Fredrikson, G. & Nilsson, J., 2011, I: Journal of Internal Medicine. 269, s. 546-556

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Regulatory T Cell 100%
  • CD25 40%
  • Cells 25%
  • Immunization 25%
  • Antibodies 14%

• Immunization of apoE-/- mice with aldehyde-modified fibronectin inhibits the development of atherosclerosis.

  Dunér, P., To, F., Beckmann, K., Björkbacka, H., Nordin Fredrikson, G., Nilsson, J. & Bengtsson, E., 2011, I: Cardiovascular Research. 91, 3, s. 528-536

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Aldehyde 100%
  • Fibronectin 100%
  • Malonaldehyde 88%
  • Antibodies 33%
  • Matrix Protein 22%
  197 Nedladdningar (Pure)

• Pleiotropic Effects of GIP on Islet Function Involve Osteopontin

  Lyssenko, V., Eliasson, L., Kotova, O., Pilgaard, K., Wierup, N., Salehi, S. A., Wendt, A., Jonsson, A., De Marinis, Y. Z., Berglund, L., Taneera, J., Balhuizen, A., Hansson, O., Osmark, P., Dunér, P., Brons, C., Stancakova, A., Kuusisto, J., Bugliani, M. & Saxena, R. & 19 andra, Ahlqvist, E., Kieffer, T. J., Tuomi, T., Isomaa, B., Melander, O., Sonestedt, E., Orho-Melander, M., Nilsson, P., Bonetti, S., Bonadonna, R., Miccoli, R., DelPrato, S., Marchetti, P., Madsbad, S., Poulsen, P., Vaag, A., Laakso, M., Gomez, M. & Groop, L., 2011, I: Diabetes. 60, 9, s. 2424-2433

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Osteopontin 100%
  • Insulin Release 38%
  • Beta Cell 35%
  • Cell Proliferation 30%
  • Insulin 23%
• 2010

  Fc{gamma}RIIB Inhibits the Development of Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice.

  Zhao, M., Wigren, M., Dunér, P., Kolbus, D., Berg, K., Björkbacka, H., Nilsson, J. & Nordin Fredrikson, G., 2010, I: Journal of Immunology. 184, 5, s. 2253-2260

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Mouse 100%
  • Density 100%
  • Immune System 12%
  • Blood Plasma 12%
  • B Cell 12%

• Immune responses against aldehyde-modified laminin accelerate atherosclerosis in Apoe(-/-) mice.

  Dunér, P., To, F., Berg, K., Alm, R., Björkbacka, H., Engelbertsen, D., Nordin Fredrikson, G., Nilsson, J. & Bengtsson, E., 2010, I: Atherosclerosis. 212, 2, s. 457-465

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Immune Response 100%
  • Laminin 100%
  • Blood Plasma 15%
  • Human 7%
  • Autoimmunity 7%
  190 Nedladdningar (Pure)
• 2009

  Atheroprotective Effects of Alum Are Associated With Capture of Oxidized LDL Antigens and Activation of Regulatory T Cells.

  Wigren, M., Kolbus, D., Dunér, P., Berg, K., Björkbacka, H., Bengtsson, E., Nordin Fredrikson, G. & Nilsson, J., 2009, I: Circulation Research. 104, s. E62-E70

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Regulatory T Cell 100%
  • Apolipoprotein E Knockout Mouse 100%
  • Alum 100%
  • Vaccine 42%
  • C57BL/6 28%

• Evidence Of A Role Of T Regulatory Cells Mediating Atheroprotection By APO B 100 Peptide Immunization

  Wigren, M., Kolbus, D., Dunér, P., Björkbacka, H., Nordin Fredrikson, G. & Nilsson, J., 2009, I: Atherosclerosis Supplements. 10, 2, s. e885-e885

  Forskningsoutput: Tidskriftsbidrag › Publicerat konferensabstract › Peer review

• Immune responses against fibronectin modified by lipoprotein oxidation and their association with cardiovascular disease.

  Dunér, P., To, F., Alm, R., Goncalves, I., Nordin Fredrikson, G., Hedblad, B., Berglund, G., Nilsson, J. & Bengtsson, E., 2009, I: Journal of Internal Medicine. Feb 14., s. 593-603

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Cardiovascular Disease 100%
  • Lipoprotein 100%
  • Aldehyde 100%
  • Immune Response 100%
  • Alpha Oxidation 100%

• Immune Responses Aginst Aldehyde Modified Extracellular Matrix in Atherosclerosis

  Dunér, P., 2009, Department of Clinical Sciences, Lund University. 113 s.

  Forskningsoutput: Avhandling › Doktorsavhandling (sammanläggning)

  Fil

  • Matrix Protein 100%
  • Malonaldehyde 100%
  • Aldehyde 100%
  • Oxidation 80%
  • Fibronectin 60%
  383 Nedladdningar (Pure)
• 2007

  A constitutive endogenous osteopontin production is important for macrophage function and differentiation.

  Nyström, T., Dunér, P. & Hultgårdh, A., 2007, I: Experimental Cell Research. 313, 6, s. 1149-1160

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Macrophage Differentiation 100%
  • Starvation 100%
  • Macrophage 50%
  • Apoptosis 16%
  • Monocyte 8%