Personlig profil
Forskning
Cancer Target Group– molecular and fuctional analysis in lymphoid proliferative disorders
Our research focus on finding biological answers to clinically important questions involving improved diagnosis, stratification and treatment of patients with lymphoma. The main problem with successfully treating cancer lies in the heterogeneity of the malignancy, and tools that may capture that heterogeneity and provide evidence for variations in tumor-related signaling pathways and/or interaction with surrounding immune microenvironment is a holy grail. To advance the field, we collaborate closely with clinicians to perform advanced molecular investigations of patient material derived from within and outside clinical trials, including sequencing, spatial omics technologies, serum protein profiling and functional screening.
Ämnesklassifikation (UKÄ)
- Cancer och onkologi
Expertis relaterad till FN:s globala mål
2015 godkände FN:s medlemsstater 17 Globala mål för en hållbar utveckling, för att utrota fattigdomen, skydda planeten och garantera välstånd för alla. Den här personens arbete relaterar till följande Globala mål:
-
SDG 3 – God hälsa och välbefinnande
Fingeravtryck
- 1 Liknande profiler
Samarbeten under de senaste fem åren
Forskningsoutput
-
From gene expression analysis to tissue microarrays - A rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies
Ek, S., Andreasson, U., Hober, S., Kampf, C., Ponten, F., Uhlen, M., Merz, H. & Borrebaeck, C., 2006, I: Molecular & Cellular Proteomics. 5, 6, s. 1072-1081Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
-
Nuclear expression of the Non-B Cell Lineage Sox11 Transcription Factor Identifies Mantle Cell Lymphoma
Ek, S., Dictor, M., Jerkeman, M., Jirström, K. & Borrebaeck, C., 2008, I: Blood. 111, 2, s. 800-805Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
Öppen tillgång -
Knock-down of SOX11 induces autotaxin-dependent increase in proliferation in vitro and more aggressive tumors in vivo
Conrotto, P., Andreasson, U., Kuci, V., Borrebaeck, C. & Ek, S., 2011, I: Molecular Oncology. 5, s. 527-537Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
-
Distinct immune microenvironments in ovarian cancer subtypes indicate potential for immunotherapies
Meldgaard Frank, A., Carlsson, E., Ouyang, H., Olsson, L. M., Mateiou, C., Ek, S., Sundfeldt, K. & Sandström Gerdtsson, A., 2026 feb. 21, I: Journal of Translational Medicine. 15 s.Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
Öppen tillgång -
The Progression of Mycosis Fungoides During Treatment with Mogamulizumab: A BIO-MUSE Case Study of the Tumor and Immune Response in Peripheral Blood and Tissue
Johansson, A., Kalliara, E., Belfrage, E., Alling, T., Pyl, P. T., Sandström Gerdtsson, A., Gullberg, U., Porwit, A., Drott, K. & Ek, S., 2025, I: Biomedicines. 13, s. 1-29 186.Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
Öppen tillgång
-
Targeted soluble proteomics, a non-invasive method to optimizing targeted treatment in the relapsed setting - translational studies connected to the Nordic mantle cell lymphoma (MCL) Group VALERIA and PHILEMON clinical trials
Ek, S. (PI)
Fru Berta Kamprads stiftelse för utforskning och bekämpning av cancersjukdomar
2026/01/01 → 2028/03/08
Projekt: Forskning
-
A cellular and molecular dissection of the lymphoma tumor immune microenvironment to understand and address treatment resistances
Ek, S. (PI)
2025/01/01 → 2028/12/31
Projekt: Forskning
-
MULTIPLY: MULITlayer Predictive models for relapsed MCL after ibrutinib as first line therapY
Ek, S. (PI)
The Leukemia & Lymphoma Society
2024/01/08 → 2027/12/08
Projekt: Forskning
-
Fluorescensmikroskop
Ek, S. (PI)
IngaBritt och Arne Lundbergs Forskningsstiftelse
2023/09/25 → 2026/09/21
Projekt: Forskning
Aktiviteter
- 3 Arrangerat workshop/ seminarium/ kurs
-
LUCC - Immunology, tumour microenvironment & metastasis: 5th Minisymposium - Applications of digital spatial profiling
Leandersson, K. (organisatör), Sandström Gerdtsson, A. (organisatör), Ek, S. (presentatör) & Christensson, G. (presentatör)
2024 feb. 9Aktivitet: Deltagit i eller arrangerat evenemang › Arrangerat workshop/ seminarium/ kurs
-
LUCC - Friday Cancer Centre Seminars: "Improved understanding of B-cell lymphomas through spatialomic technologies"
Jerkeman, M. (organisatör) & Ek, S. (presentatör)
2023 nov. 24Aktivitet: Deltagit i eller arrangerat evenemang › Arrangerat workshop/ seminarium/ kurs
-
LUCC - Breast: Seminar
Alkner, S. (organisatör), Saal, L. (organisatör), Ek, S. (presentatör), Pietras, K. (presentatör), Loman, N. (presentatör) & Saal, L. (presentatör)
2023 mars 16Aktivitet: Deltagit i eller arrangerat evenemang › Arrangerat workshop/ seminarium/ kurs