Sevda Gheibi

Sökresultat

• 2023

  EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion

  Blanchi, B., Taurand, M., Colace, C., Thomaidou, S., Audeoud, C., Fantuzzi, F., Sawatani, T., Gheibi, S., Sabadell-Basallote, J., Boot, F. W. J., Chantier, T., Piet, A., Cavanihac, C., Pilette, M., Balguerie, A., Olleik, H., Carlotti, F., Ejarque, M., Fex, M. & Mulder, H. & 8 andra, Cnop, M., Eizirik, D. L., Jouannot, O., Gaffuri, A. L., Czernichow, P., Zaldumbide, A., Scharfmann, R. & Ravassard, P., 2023 okt., I: Molecular Metabolism. 76, 101772.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Insulin Release 100%
  • Cell Function 66%
  • Glucose 66%
  • Insulin 33%
  • Transfer Gene 33%

• Reduced Expression Level of Protein Phosphatase PPM1E Serves to Maintain Insulin Secretion in Type 2 Diabetes

  Gheibi, S., Cataldo, L. R., Hamilton, A., Huang, M., Kalamajski, S., Fex, M. & Mulder, H., 2023 apr. 1, I: Diabetes. 72, 4, s. 455-466 12 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Insulin Release 100%
  • Glucose 71%
  • Regulatory Mechanism 28%
  • AMP-activated Protein Kinase 28%
  • Insulin 14%

• Anti-oxidant effect of nitrite in the pancreatic islets of type 2 diabetic male rats

  Ghasemi, A., Gheibi, S., Kashfi, K. & Jeddi, S., 2023 apr., I: Iranian Journal of Basic Medical Sciences. 26, 4, s. 420-428 9 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Rat 100%
  • Antioxidant 100%
  • Nitrite 100%
  • Non Insulin Dependent Diabetes Mellitus 71%
  • Oxidative Stress 60%

• Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets

  Bacos, K., Perfilyev, A., Karagiannopoulos, A., Cowan, E., Ofori, J. K., Bertonnier-Brouty, L., Rönn, T., Lindqvist, A., Luan, C., Ruhrmann, S., Ngara, M., Nilsson, Å., Gheibi, S., Lyons, C. L., Lagerstedt, J. O., Barghouth, M., Esguerra, J. L., Volkov, P., Fex, M. & Mulder, H. & 7 andra, Wierup, N., Krus, U., Artner, I., Eliasson, L., Prasad, R. B., Cataldo, L. R. & Ling, C., 2023, I: The Journal of clinical investigation. 133, 4, e163612.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Gene 100%
  • Candidate Gene 100%
  • Insulin Release 100%
  • PAX5 100%
  • Knockout Mouse 25%
• 2022

  Hydrogen sulfide potentiates the protective effects of nitrite against myocardial ischemia-reperfusion injury in type 2 diabetic rats

  Jeddi, S., Gheibi, S., Afzali, H., Carlström, M., Kashfi, K. & Ghasemi, A., 2022, I: Nitric Oxide - Biology and Chemistry. 124, s. 15-23 9 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Myocardial Ischemia Reperfusion Injury 100%
  • Nitrite 100%
  • Non Insulin Dependent Diabetes Mellitus 64%
  • Sodium Hydrosulfide 47%
  • Intraperitoneal Injection 11%

• Ribosomal biogenesis regulator DIMT1 controls β-cell protein synthesis, mitochondrial function, and insulin secretion

  Verma, G., Bowen, A., Gheibi, S., Hamilton, A., Muthukumar, S., Cataldo, L. R., Asplund, O., Esguerra, J., Karagiannopoulos, A., Lyons, C., Cowan, E., Bellodi, C., Prasad, R., Fex, M. & Mulder, H., 2022, I: The Journal of biological chemistry. 298, 3, 101692.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Insulin Release 100%
  • Protein Biosynthesis 100%
  • Transferase 100%
  • Protein Synthesis 100%
  • Insulin 28%

• The human batokine EPDR1 regulates β-cell metabolism and function

  Cataldo, L. R., Gao, Q., Argemi-Muntadas, L., Hodek, O., Cowan, E., Hladkou, S., Gheibi, S., Spégel, P., Prasad, R. B., Eliasson, L., Scheele, C., Fex, M., Mulder, H. & Moritz, T., 2022, I: Molecular Metabolism. 66, 101629.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Cell Function 100%
  • Glucose 61%
  • Messenger RNA 23%
  • Mass Spectrometry 16%
  • Upregulation 16%
• 2021

  Discovery of thymosin β4 as a human exerkine and growth factor

  Gonzalez-Franquesa, A., Stocks, B., Borg, M. L., Kuefner, M., Dalbram, E., Nielsen, T. S., Agrawal, A., Pankratova, S., Chibalin, A. V., Karlsson, H. K. R., Gheibi, S., Björnholm, M., Jørgensen, N. R., Clemmensen, C., Hostrup, M., Treebak, J. T., Krook, A., Zierath, J. R. & Deshmukh, A. S., 2021 nov. 1, I: American Journal of Physiology - Cell Physiology. 321, 5, s. C770-C778

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Mouse 100%
  • Blood Plasma 100%
  • Mass Spectrometry 100%
  • Myotube 100%

• Sodium hydrosulfide has no additive effects on nitrite-inhibited renal gluconeogenesis in type 2 diabetic rats

  Jeddi, S., Gheibi, S., Kashfi, K. & Ghasemi, A., 2021 okt. 15, I: Life Sciences. 283, 119870.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Rat 100%
  • Nitrite 100%
  • Non Insulin Dependent Diabetes Mellitus 81%
  • Gene 44%
  • Messenger RNA 33%

• Long-term co-administration of sodium nitrite and sodium hydrosulfide inhibits hepatic gluconeogenesis in male type 2 diabetic rats: Role of PI3K-Akt-eNOS pathway

  Jeddi, S., Gheibi, S., Carlström, M., Kashfi, K. & Ghasemi, A., 2021 jan. 15, I: Life Sciences. 265, 118770.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Nitrite 100%
  • Sodium Hydrosulfide 100%
  • Glucose 6 Phosphatase 12%
• 2020

  Protective effect of intermediate doses of hydrogen sulfide against myocardial ischemia-reperfusion injury in obese type 2 diabetic rats

  Jeddi, S., Gheibi, S., Kashfi, K., Carlström, M. & Ghasemi, A., 2020, I: Life Sciences. 256, 117855.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Myocardial Ischemia Reperfusion Injury 100%
  • Non Insulin Dependent Diabetes Mellitus 85%
  • Lyase 28%
  • Fat 14%
  • Streptozotocin 14%