Yutaka Sugihara

Sökresultat

• 2021

  An observational study on the molecular profiling of primary melanomas reveals a progression dependence on mitochondrial activation

  Gil, J., Rezeli, M., Lutz, E. G., Kim, Y., Sugihara, Y., Malm, J., Semenov, Y. R., Yu, K. H., Nguyen, N., Wan, G., Kemény, L. V., Kárpáti, S., Németh, I. B. & Marko‐varga, G., 2021 dec., I: Cancers. 13, 23, 6066.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Melanoma 100%
  • Observational Studies 93%
  • Antigen Presentation 32%
  • Post Translational Protein Processing 31%
  • RNA Transport 22%

• The Human Melanoma Proteome Atlas-Complementing the melanoma transcriptome

  Betancourt, L. H., Gil, J., Sanchez, A., Kuras, M., Velasquez, E., Kim, Y., Sugihara, Y., Parada, I. P., Appelqvist, R., Wieslander, E., Welinder, C., de Almeida, N. P., Woldmar, N., Marko-Varga, M., Eriksson, J., Baldetorp, B., Ingvar, C., Olsson, H., Lundgren, L., Lindberg, H., & 15 andraOskolas, H., Lee, B., Berge, E., Sjögren, M., Eriksson, C., Kim, D., Kwon, H. J., Rezeli, M., Malm, J., Horvath, P., Horvatovich, P., Miliotis, T., Ekedahl, H., Marko-Varga, G. & et al., 2021, I: Clinical and Translational Medicine. 11, 7, s. 1-25 e451.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Atlases 100%
  • Proteome 97%
  • Transcriptome 85%
  • Melanoma 77%
  • Proteomics 36%

• The human melanoma proteome atlas-Defining the molecular pathology

  Betancourt, L. H., Gil, J., Kim, Y., Doma, V., Çakır, U., Sanchez, A., Murillo, J. R., Kuras, M., Parada, I. P., Sugihara, Y., Appelqvist, R., Wieslander, E., Welinder, C., Velasquez, E., de Almeida, N. P., Woldmar, N., Marko-Varga, M., Pawłowski, K., Eriksson, J., Szeitz, B., & 37 andraBaldetorp, B., Ingvar, C., Olsson, H., Lundgren, L., Lindberg, H., Oskolas, H., Lee, B., Berge, E., Sjögren, M., Eriksson, C., Kim, D., Kwon, H. J., Knudsen, B., Rezeli, M., Hong, R., Horvatovich, P., Miliotis, T., Nishimura, T., Kato, H., Steinfelder, E., Oppermann, M., Miller, K., Florindi, F., Zhou, Q., Domont, G. B., Pizzatti, L., Nogueira, F. C. S., Horvath, P., Szadai, L., Timar, J., Karpati, S., Szasz, A. M., Malm, J., Fenyö, D., Ekedahl, H., Németh, I. B. & Marko-Varga, G., 2021, I: Clinical and Translational Medicine. 11, 7, s. 1-20 e473.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Molecular Pathology 100%
  • Atlases 93%
  • Proteome 91%
  • Melanoma 72%
  • Neoplasms 28%
• 2020

  Amyloid-specific extraction using organic solvents

  Kamiie, J., Aihara, N., Uchida, Y., Kobayashi, D., Yoshida, Y., Kuroda, T., Sakaue, M., Sugihara, Y., Rezeli, M. & Marko-Varga, G., 2020, I: MethodsX. 7, 100770.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Trifluoroethanol 100%
  • Dimethylformamide 69%
  • Amyloid 69%
  • Dimethyl Sulfoxide 69%
  • Formaldehyde 68%

• Identification and validation of VEGFR2 kinase as a target of voacangine by a systematic combination of DARTS and MSI

  Kim, Y., Sugihara, Y., Kim, T. Y., Cho, S. M., Kim, J. Y., Lee, J. Y., Yoo, J. S., Song, D., Han, G., Rezeli, M., Welinder, C., Appelqvist, R., Marko-Varga, G. & Kwon, H. J., 2020 mars 27, I: Biomolecules. 10, 4, 508.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • voacangine 100%
  • Imaging Mass Spectrometry 61%
  • Vascular Endothelial Growth Factor Receptor-2 58%
  • Drug Combinations 48%
  • Mass Spectrometry 42%

• Novel functional proteins coded by the human genome discovered in metastases of melanoma patients

  Sanchez, A., Kuras, M., Murillo, J. R., Pla, I., Pawlowski, K., Szasz, A. M., Gil, J., Nogueira, F. C. S., Perez-Riverol, Y., Eriksson, J., Appelqvist, R., Miliotis, T., Kim, Y., Baldetorp, B., Ingvar, C., Olsson, H., Lundgren, L., Ekedahl, H., Horvatovich, P., Sugihara, Y., & 8 andraWelinder, C., Wieslander, E., Kwon, H. J., Domont, G. B., Malm, J., Rezeli, M., Betancourt, L. H. & Marko-Varga, G., 2020 juni, I: Cell Biology and Toxicology. 36, 3, s. 261-272 12 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Human Genome 100%
  • Melanoma 79%
  • Neoplasm Metastasis 58%
  • Proteomics 43%
  • Protein 39%
• 2019

  Challenging the heterogeneity of disease presentation in malignant melanoma—impact on patient treatment

  Marcell Szasz, A., Malm, J., Rezeli, M., Sugihara, Y., Betancourt, L. H., Rivas, D., Gyorffy, B. & Marko-Varga, G., 2019, I: Cell Biology and Toxicology. 35, 1, s. 1-14

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Heterogeneity 100%
  • Mutation 45%
  • Time 38%
  • Neoplasms 34%
  • Modification 30%

• Clinical protein science in translational medicine targeting malignant melanoma

  Gil, J., Betancourt, L. H., Pla, I., Sanchez, A., Appelqvist, R., Miliotis, T., Kuras, M., Oskolas, H., Kim, Y., Horvath, Z., Eriksson, J., Berge, E., Burestedt, E., Jönsson, G., Baldetorp, B., Ingvar, C., Olsson, H., Lundgren, L., Horvatovich, P., Murillo, J. R., & 18 andraSugihara, Y., Welinder, C., Wieslander, E., Lee, B., Lindberg, H., Pawłowski, K., Kwon, H. J., Doma, V., Timar, J., Karpati, S., Szasz, A. M., Németh, I. B., Nishimura, T., Corthals, G., Rezeli, M., Knudsen, B., Malm, J. & Marko-Varga, G., 2019, I: Cell Biology and Toxicology. 35, 4, s. 293-332

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Translational Medical Research 100%
  • Melanoma 73%
  • Proteomics 50%
  • Protein 36%
  • Proteins 32%

• Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data

  Betancourt, L. H., Pawłowski, K., Eriksson, J., Szasz, A. M., Mitra, S., Pla, I., Welinder, C., Ekedahl, H., Broberg, P., Appelqvist, R., Yakovleva, M., Sugihara, Y., Miharada, K., Ingvar, C., Lundgren, L., Baldetorp, B., Olsson, H., Rezeli, M., Wieslander, E., Horvatovich, P., & 3 andraMalm, J., Jönsson, G. & Marko-Varga, G., 2019 mars 26, I: Scientific Reports. 9, 1, 5154.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Firearms 100%
  • Proteomics 80%
  • Melanoma 72%
  • Survival 48%
  • Proteins 25%

• Optimization of sample preparation for transporter protein quantification in tissues by LC–MS/MS

  Jankovskaja, S., Kamiie, J., Rezeli, M., Gustavsson, L., Sugihara, Y., Miliotis, T., Ruzgas, T. & Marko-Varga, G., 2019 feb. 5, I: Journal of Pharmaceutical and Biomedical Analysis. 164, s. 9-15 7 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Sample Preparation 100%
  • Cell Membrane 66%
  • Protein 49%
  • Proteins 43%
  • Plasma 36%

• The hidden story of heterogeneous B-raf V600E mutation quantitative protein expression in metastatic melanoma—association with clinical outcome and tumor phenotypes

  Betancourt, L. H., Szasz, A. M., Kuras, M., Murillo, J. R., Sugihara, Y., Pla, I., Horvath, Z., Pawłowski, K., Rezeli, M., Miharada, K., Gil, J., Eriksson, J., Appelqvist, R., Miliotis, T., Baldetorp, B., Ingvar, C., Olsson, H., Lundgren, L., Horvatovich, P., Welinder, C., & 8 andraWieslander, E., Kwon, H. J., Malm, J., Nemeth, I. B., Jönsson, G., Fenyö, D., Sanchez, A. & Marko-Varga, G., 2019, I: Cancers. 11, 12, 1981.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Phenotype 100%
  • Mutation 93%
  • Melanoma 86%
  • Proteins 61%
  • Neoplasms 53%
• 2018

  Endogenous expression mapping of malignant melanoma by mass spectrometry imaging

  Sugihara, Y., Rivas, D., Malm, J., Szasz, M., Kwon, H., Baldetorp, B., Olsson, H., Ingvar, C., Rezeli, M., Fehniger, T. E. & Marko-Varga, G., 2018 aug. 6, I: Clinical and Translational Medicine. 7, s. 1-9 22.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Mass Spectrometry 100%
  • Melanoma 92%
  • Neoplasms 35%
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry 29%
  • Disease Progression 19%

• Evaluation of Drug Exposure and Metabolism in Locust and Zebrafish Brains Using Mass Spectrometry Imaging

  Villacrez, M., Hellman, K., Ono, T., Sugihara, Y., Rezeli, M., Ek, F., Marko-Varga, G. & Olsson, R., 2018 aug. 15, I: ACS Chemical Neuroscience. 9, 8, s. 1994-2000 7 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  • Grasshoppers 100%
  • Imaging Mass Spectrometry 92%
  • Drug Evaluation 87%
  • Zebrafish 71%
  • Mass Spectrometry 63%
• 2017

  Correlation of histopathologic characteristics to protein expression and function in malignant melanoma

  Welinder, C., Pawlowski, K., Szász, M., Yakovleva, M., Sugihara, Y., Malm, J., Jönsson, G. B., Ingvar, C., Lundgren, L., Baldetorp, B., Olsson, H., Rezeli, M., Laurell, T., Wieslander, E. & Marko-Varga, G., 2017 apr. 1, I: PLoS ONE. 12, 4, e0176167.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Melanoma 100%
  • Proteomics 55%
  • Proteins 44%
  • Feasibility Studies 31%
  • Neoplasms 29%

• Limited tumor tissue drug penetration contributes to primary resistance against angiogenesis inhibitors

  Torok, S., Rezeli, M., Kelemen, O., Vegvari, A., Watanabe, K., Sugihara, Y., Tisza, A., Marton, T., Kovacs, I., Tovari, J., Laszlo, V., Helbich, T. H., Hegedus, B., Klikovits, T., Hoda, M. A., Klepetko, W., Paku, S., Marko-Varga, G. & Dome, B., 2017, I: Theranostics. 7, 2, s. 400-412 13 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  • Angiogenesis Inhibitors 100%
  • Sunitinib 53%
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry 49%
  • vatalanib 48%
  • Pharmaceutical Preparations 34%
• 2015

  A protein deep sequencing evaluation of metastatic melanoma tissues.

  Welinder, C., Pawlowski, K., Sugihara, Y., Yakovleva, M., Jönsson, G. B., Ingvar, C., Lundgren, L., Baldetorp, B., Olsson, H., Rezeli, M., Jansson, B., Laurell, T., Fehniger, T., Döme, B., Malm, J., Wieslander, E., Nishimura, T. & Marko-Varga, G., 2015, I: PLoS ONE. 10, 4, e0123661.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Protein Sequence Analysis 100%
  • High-Throughput Nucleotide Sequencing 79%
  • Melanoma 68%
  • Protein Databases 30%
  • Proteins 26%
  225 Nedladdningar (Pure)

• Localization of Sunitinib in in vivo Animal and in vitro Experimental Models by MALDI Mass Spectrometry Imaging

  James, C., Sugihara, Y., Török, S., Döme, B., Fehniger, T., Marko-Varga, G. & Végvári, Á., 2015, I: Analytical and Bioanalytical Chemistry. 407, 8, s. 2245-2253

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Fil

  • Sunitinib 100%
  • Imaging Mass Spectrometry 78%
  • Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry 71%
  • Mass Spectrometry 53%
  • Theoretical Models 48%
  213 Nedladdningar (Pure)
• 2014

  Clinical initiatives linking Japanese and Swedish healthcare resources on cancer studies utilizing Biobank Repositories.

  Nishimura, T., Kawamura, T., Sugihara, Y., Bando, Y., Sakamoto, S., Nomura, M., Ikeda, N., Ohira, T., Fujimoto, J., Tojo, H., Hamakubo, T., Kodama, T., Andersson, R., Fehniger, T. E., Kato, H. & Marko-Varga, G., 2014, I: Clinical and Translational Medicine. 3, 1, 61.

  Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

  Öppen tillgång

  Fil

  • Small Cell Lung Carcinoma 100%
  • Delivery of Health Care 91%
  • Lung Neoplasms 71%
  • Sweden 58%
  • Japan 49%
  315 Nedladdningar (Pure)