Projektinformation
Beskrivning
Around 700 patients are diagnosed with epithelial ovarian cancer (EOC) in Sweden each year, making OC the eighth most common female cancer. Due to the late-stage at first diagnose, secondary to vague symptoms, the prognosis of EOC is poor, with a five-year survival rate of 49%. Primary debulking surgery (PDS) followed by platinum-based postoperative chemotherapy is the standard of care for advanced ovarian cancer (AOC). In cases where surgery is not primarily possible, patients receive neoadjuvant chemotherapy followed by interval debulking surgery (IDS). The extent of surgery depends on the histopathological type and spread of the tumor. In cases where PDS is not the primary therapeutic choice, it is necessary to characterize the type of tumor in order to develop a plan for chemotherapy. The extent of the abdominal tumor must be well characterized preoperatively in order to plan surgery effectively and achieve maximal radicality. One way of characterizing the extent of the tumor involves the surgeon quantifying it numerically in the peritoneal cavity, using what is known as the peritoneal cancer index (PCI). The full therapy plan is a complex process involving a multidisciplinary approach which includes oncologists, radiologists, pathologists and gynecologists. The centralization of cancer care to tertiary centers has resulted in highly specialized pathology, radiology, oncology and surgical departments, and has improved outcomes and survival rates.
The overall aim of this thesis was to analyze preoperative and perioperative methods of diagnosis from a multidisciplinary perspective, in order to improve the therapy plan which is crucial for patients’ survival.
The overall aim of this thesis was to analyze preoperative and perioperative methods of diagnosis from a multidisciplinary perspective, in order to improve the therapy plan which is crucial for patients’ survival.
Status | Slutfört |
---|---|
Gällande start-/slutdatum | 2019/01/01 → 2022/12/02 |