Forskningsoutput per år
Forskningsoutput per år
Projektinformation
Beskrivning
RBCs are an important target in the life cycle of all human Plasmodium parasites, and blood group polymorphism distribution between different populations in endemic and non–endemic regions is often an indicator that a glycoprotein is a potential ligand on the RBC surface. This research will focus on blood group polymorphism in less well–studied regions in South East Asia, where malaria is endemic. We will investigate what RBC surface molecules are used by P.vivax and P. knowlesi other than those which have already been described (Duffy and Glycophorin A).
Aim 1: To investigate the blood group antigen polymorphism in individuals in Thailand.
Aim 2: To culture P. vivax and P. knowlesi and to test RBCs of different blood group phenotypes for their invasion susceptibility.
Aim 3: To investigate the RBC specificity of autoantibodies made in patients with, or recovering from, malaria.
Aim 1: To investigate the blood group antigen polymorphism in individuals in Thailand.
Aim 2: To culture P. vivax and P. knowlesi and to test RBCs of different blood group phenotypes for their invasion susceptibility.
Aim 3: To investigate the RBC specificity of autoantibodies made in patients with, or recovering from, malaria.
| Status | Slutfört |
|---|---|
| Gällande start-/slutdatum | 2016/05/01 → 2020/05/20 |
FN:s Globala mål
År 2015 godkände FN:s medlemsstater 17 Globala mål för en hållbar utveckling, utrota fattigdomen, skydda planeten och garantera välstånd för alla. Projektet relaterar till följande Globala mål:
Ämnesklassifikation (UKÄ)
- Hematologi
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Characterization of GYP*Mur and novel GYP*Bun-like hybrids in Thai blood donors reveals a qualitatively altered s antigen
Jongruamklang, P., Grimsley, S., Thornton, N., Robb, J., Olsson, M. L. & Storry, J. R., 2020 juli, I: Vox Sanguinis. 115, 5, s. 472-477 6 s.Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
Öppen tillgång -
Studies of Thai blood group and platelet polymorphism. Implications for malaria susceptibility.
Jongruamklang, P., 2020, Lund: Lund University, Faculty of Medicine. 97 s.Forskningsoutput: Avhandling › Doktorsavhandling (sammanläggning)
Öppen tillgångFil294 Nedladdningar (Pure) -
Multiple miscarriages in two sisters of Thai origin with the rare Pk phenotype caused by a novel nonsense mutation at the B3GALNT1 locus
Ricci Hagman, J., Hult, A. K., Westman, J. S., Hosseini-Maaf, B., Jongruamklang, P., Saipin, J., Bejrachandra, S. & Olsson, M. L., 2019, I: Transfusion Medicine. 29, 3, s. 202-208 7 s.Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review