Forskningsoutput per år
Forskningsoutput per år
Projektinformation
Beskrivning
Mitochondrial dysfunction is implicated in several chronic neurodegenerative disorders, such as Parkinson’s disease (PD), Amyotrophic Lateral Sclerosis (ALS) and Alzheimer's Dementia (AD) and also in patients with certain muscular disorders.
The aim of the study is to determine if defects in mitochondrial function can be detected in peripheral blood cells (platelets and white blood cells) derived from patients with chronic neurodegenerative or muscular disorders using high-resolution respirometry.
Some degree of mitochondrial involvement in the pathogenesis of all these diseases have been suggested but the exact role of the mitochondria in neurodegeneration remains to be elucidated.
The aim of the study is to determine if defects in mitochondrial function can be detected in peripheral blood cells (platelets and white blood cells) derived from patients with chronic neurodegenerative or muscular disorders using high-resolution respirometry.
Some degree of mitochondrial involvement in the pathogenesis of all these diseases have been suggested but the exact role of the mitochondria in neurodegeneration remains to be elucidated.
| Akronym | MIND |
|---|---|
| Status | Pågående |
| Gällande start-/slutdatum | 2011/05/02 → … |
FN:s Globala mål
År 2015 godkände FN:s medlemsstater 17 Globala mål för en hållbar utveckling, utrota fattigdomen, skydda planeten och garantera välstånd för alla. Projektet relaterar till följande Globala mål:
Ämnesklassifikation (UKÄ)
- Neurologi
- Cell- och molekylärbiologi
- Biomedicinsk laboratorievetenskap/teknologi
Fria nyckelord
- mitochondria
- blood cells
- neurodegeneration
- Parkinson's disease
- high-resolution respirometry
- ALS
- muscular disorders
Forskningsoutput
- 2 Artikel i vetenskaplig tidskrift
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Mitochondrial Respiratory Function in Peripheral Blood Cells from Huntington's Disease Patients
EHINGER, J., Morota, S., Hansson, M., Paul-Visse, G. & Elmer, E., 2016 sep., I: Movement Disorders Clinical Practice. 3, 5, s. 472–482Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
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Mitochondrial dysfunction in blood cells from amyotrophic lateral sclerosis patients.
Ehinger, J., Morota, S., Hansson, M., Paul-Visse, G. & Elmer, E., 2015, I: Journal of Neurology. 262, 6, s. 1493-1503Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
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MitoAge: Mitochondrial function in human aging
Ehinger, J. (PI), Elmer, E. (CoI), Westerlund, E. (Forskare), Åsander Frostner, E. (Forskningsingenjör), Chamkha, I. (Forskare), Marelsson, S. (Forskare) & Sjövall, F. (Forskare)
2022/08/01 → …
Projekt: Forskning
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MITOEAGLE: EU FP Horizon 2020 COST Action CA15203 MITOEAGLE
Elmer, E. (PI), Åsander Frostner, E. (Forskningsingenjör), Hansson, M. (Forskare), Sjövall, F. (Forskare), Piel, S. (Forskarstuderande), Ehinger, J. (Forskarstuderande), Karlsson, M. (Forskarstuderande), Westerlund, E. (Forskarstuderande), Tavecchio, M. (Forskare) & Gnaiger, E. (PI)
2016/09/12 → 2020/09/11
Projekt: Nätverk