Projektinformation
Beskrivning
The dissertation deals with identifying the mechanisms of dexamethasone resistance in B-ALL, and mechanisms of venetoclax resistance in T-ALL. We have also identified mono or combination therapies to overcome this resistance.
Populärvetenskaplig beskrivning
Acute lymphoblastic leukemia comprises both B-ALL and T-ALL. The dissertation deals with identifying the mechanisms of resistance to a glucocorticoid, dexamethasone in B-ALL and a BCL2 inhibitor, venetoclax in T-ALL. We have also identified mono or combination therapies to overcome this resistance.
| Status | Slutfört |
|---|---|
| Gällande start-/slutdatum | 2017/08/01 → 2021/10/31 |
Ämnesklassifikation (UKÄ)
- Cell- och molekylärbiologi
- Andra medicinska och farmaceutiska grundvetenskaper