Forskningsoutput per år
Forskningsoutput per år
Projektinformation
Beskrivning
In order to achieve precise directed neural dierentiation in vitro
we need to understand the gene regulatory mechanisms behind in vivo neural tube
patterning. We implement a 3D computational model of brain patterning to simulate
this process. The mathematical model is set up by unifying two gene regulatory
network models for patterning of the dorsoventral and rostrocaudal axes on the basis
of WNT-signaling.
we need to understand the gene regulatory mechanisms behind in vivo neural tube
patterning. We implement a 3D computational model of brain patterning to simulate
this process. The mathematical model is set up by unifying two gene regulatory
network models for patterning of the dorsoventral and rostrocaudal axes on the basis
of WNT-signaling.
| Status | Pågående |
|---|---|
| Gällande start-/slutdatum | 2019/01/01 → … |
Forskningsoutput
- 1 Artikel i vetenskaplig tidskrift
-
Neural tube patterning: from a minimal model for rostrocaudal patterning toward an integrated 3D model
Brambach, M., Ernst, A., Nolbrant, S., Drouin-Ouellet, J., Kirkeby, A., Parmar, M. & Olariu, V., 2021 juni 25, I: iScience. 24, 6, 16 s., 102559.Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review
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