SAVE- sen avnavling vid behov av ventilation

More than one million neonates worldwide suffer from permanent brain damage or die as a result of oxygen deprivation during birth. To reduce the number of injuries and deaths, neonatal cardiopulmonary resuscitation (neonatal CPR) can be used. In Sweden, about 5% of full-term newborns, or 5,000 children, require active breathing assistance immediately after birth. Currently, when a child is born, the umbilical cord is cut and the neonate is taken to a separate location for neonatal CPR, which separates the child from the mother.
However, the SAVE study has developed a new method for neonatal CPR that can be performed near the mother with an intact umbilical cord. The SAVE randomized study is now recruiting patients. Children in need of neonatal CPR will be randomly assigned to either receive standard care, which involves immediate umbilical cord clamping and cutting, or to be placed in the mother's bed for the first three minutes with intact umbilical cord circulation using the SAVE method. A pilot study in Nepal has shown positive effects with improved vitality and oxygenation.
We will follow up with the children's initial care needs and future development, as well as the mother's attachment and breastfeeding. Additionally, in the multicenter SAVE study, we will evaluate the implementation outcomes of staff and parents' attitudes and experiences on neonatal CPR with an intact umbilical cord.
By using the SAVE method, the incidence of asphyxia-related injuries can be reduced, resulting in improved psychomotor development and overall health for the growing child. In low-income countries, the SAVE method could also lead to a reduction in newborn mortality.