Projekt per år
Bio-based 5-hydroxymethylfurfural (5-HMF) and its derivatives have attracted enormous attention due to their valuable market potential. Production of pure 5-HMF is challenging owing to the high reactivity of its functional groups and formation of by-products. In this study, an efficient continuous process for 5-HMF production in a biphasic system and its recovery at high yield and selectivity was developed. After an initial screening of different solvents, a water/dimethyl carbonate (DMC) system was selected for acid catalyzed fructose dehydration in a continuous mode using 0.23 M HCl as a catalyst. Effects of various reaction parameters on substrate conversion, product yield and selectivity, were determined. The process using 30% (w/v) fructose in water with three times the volume of DMC at 1 min residence time in a tube reactor at 200 °C provided 96.5% fructose conversion and 87.2% 5-HMF yield with a selectivity of 85.5% and 95.8% in aqueous and organic phases, respectively. Increasing the fructose concentration in the water phase to 52% gave 96.4% conversion and 74% 5-HMF yield. Using a fructose-glucose mixture as substrate had no effect on fructose conversion but affected slightly the selectivity of 5-HMF in the aqueous phase. Recovery of 5-HMF with ≥93% purity from DMC was achieved by solvent evaporation under vacuum, and improved by prior treatment with activated carbon, especially together with Na2CO3. Evaluation of the purified 5-HMF in a reaction with pentaerythritol showed comparable performance to the commercial 5-HMF in the production of a spirocyclic diol, a monomer for the production of polyesters and polyurethane.
FingeravtryckUtforska forskningsämnen för ”5-Hydroxymethylfurfural from fructose: An efficient continuous process in a water-dimethyl carbonate biphasic system with high yield product recovery”. Tillsammans bildar de ett unikt fingeravtryck.
Generosi, J., Hatti-Kaul, R., Pyo, S., Zhang, B., Turner, C., Rodriguez Meizoso, I., Wallberg, O., Hulteberg, C., Diegel, O., Ristinmaa, M., Nilsson, L. J., Palm, E., Ericsson, K., Hansen, T., Klintman, M., Stripple, J., Bauer, F., Madsen, S., Jannasch, P., Egan, N., Nielsen, T., Holmberg, K., Svantesson, A., Hall, S., Mahmoud, S., Englund Örn, O., Mankar, S., Warlin, N., Valsange, N., Sanku, M., Hasselbalch, J., Sjölin, M., Hansen, T., Chen, L., Nordin, A., Engqvist, J., Garcia Gonzalez, N., Newson, W. R., Johansson, E., Kuktaite, R., Muneer, F., Nilsson , E., Guo, Z., Ahlqvist, J. & Peric, S.
2016/09/01 → 2020/08/31