A clinical distance measure for evaluating treatment plan quality difference with Pareto fronts in radiotherapy

Kristoffer Petersson, Archonteia Kyroudi, Jean Bourhis, Crister Ceberg, Tommy Knoos, Francois Bochud, Raphaël Möckli

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

Sammanfattning

We present a clinical distance measure for Pareto front evaluation studies in radiotherapy, which we show strongly correlates (r = 0.74 and 0.90) with clinical plan quality evaluation. For five prostate cases, sub-optimal treatment plans located at a clinical distance value of >0.32 (0.28–0.35) from fronts of Pareto optimal plans, were assessed to be of lower plan quality by our (12) observers (p < .05). In conclusion, the clinical distance measure can be used to determine if the difference between a front and a given plan (or between different fronts) corresponds to a clinically significant plan quality difference.
Originalspråkengelska
Sidor (från-till)53-56
TidskriftPhysics and imaging in radiation oncology
Volym3
DOI
StatusPublished - 2017 juli

Ämnesklassifikation (UKÄ)

  • Radiologi och bildbehandling
  • Annan fysik

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