TY - GEN
T1 - A polymer neural probe with tunable flexibility
AU - Ejserholm, Fredrik
AU - Vastesson, A.
AU - Haraldsson, T.
AU - van der Wijngaart, W.
AU - Schouenborg, J.
AU - Wallman, Lars
AU - Bengtsson, Martin
PY - 2013
Y1 - 2013
N2 - A novel polymeric material, off-stoichiometry thiol-ene-epoxy (OSTE+), has been evaluated for the fabrication of neural implants. OSTE+ is easily photo-structurable and exhibits mechanical properties suitable for stable implantation of the probe into brain tissue, while being sufficiently soft at physiological temperatures to reduce living tissue damage. The facile processing of OSTE+ allows use in applications where SU-8 or polyimide currently are the materials of choice. Uniquely, OSTE+ has a Young's modulus of 1.9 GPa at 10 degrees C decreasing almost two orders of magnitude to 30 MPa at 40 degrees C, which can be compared to the Young's modulus of 2.1 GPa for SU-8. We show a probe, with nine gold electrode sites, implanted into 0.5% agar at 40 degrees C using active cooling during the implantation.
AB - A novel polymeric material, off-stoichiometry thiol-ene-epoxy (OSTE+), has been evaluated for the fabrication of neural implants. OSTE+ is easily photo-structurable and exhibits mechanical properties suitable for stable implantation of the probe into brain tissue, while being sufficiently soft at physiological temperatures to reduce living tissue damage. The facile processing of OSTE+ allows use in applications where SU-8 or polyimide currently are the materials of choice. Uniquely, OSTE+ has a Young's modulus of 1.9 GPa at 10 degrees C decreasing almost two orders of magnitude to 30 MPa at 40 degrees C, which can be compared to the Young's modulus of 2.1 GPa for SU-8. We show a probe, with nine gold electrode sites, implanted into 0.5% agar at 40 degrees C using active cooling during the implantation.
U2 - 10.1109/NER.2013.6696028
DO - 10.1109/NER.2013.6696028
M3 - Paper in conference proceeding
SP - 691
EP - 694
BT - 2013 6th International IEEE/Embs Conference on Neural Engineering (NER)
PB - IEEE - Institute of Electrical and Electronics Engineers Inc.
T2 - 6th International IEEE EMBS Conference on Neural Engineering (NER)
Y2 - 6 November 2013 through 8 November 2013
ER -