Acoustic focusing of microparticles in two-phase systems - Towards cell enrichment or medium exchange in droplets

Anna Fornell; Håkan N. Jonsson; Johan Nilsson; Maria Tenje

Acoustic focusing of microparticles in two-phase systems - Towards cell enrichment or medium exchange in droplets

Anna Fornell, Håkan N. Jonsson, Johan Nilsson, Maria Tenje

Institutionen för biomedicinsk teknik

Forskningsoutput: Kapitel i bok/rapport/Conference proceeding › Konferenspaper i proceeding › Peer review

Sammanfattning

We present a method to first laterally position microparticles inside droplets by acoustic forces and then split the droplet into three daughter droplets to achieve a 2+fold enrichment of microparticles inside the center droplet. We show that acoustic forces can be applied to both manipulate polystyrene beads (5 μm) and red blood cells inside droplets. The presented technology opens up for development of droplet operations used for medium exchange and particle concentration in droplet-based cell assays.

Originalspråk	engelska
Titel på värdpublikation	MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Förlag	Chemical and Biological Microsystems Society
Sidor	1026-1028
Antal sidor	3
ISBN (elektroniskt)	9780979806483
Status	Published - 2015
Evenemang	19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Sydkorea, Republiken Korea Varaktighet: 2015 okt. 25 → 2015 okt. 29

Konferens

Konferens	19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
Land/Territorium	Sydkorea, Republiken Korea
Ort	Gyeongju
Period	2015/10/25 → 2015/10/29

Ämnesklassifikation (UKÄ)

Biomedicinsk laboratorievetenskap/teknologi

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Link to publication in Scopus

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title = "Acoustic focusing of microparticles in two-phase systems - Towards cell enrichment or medium exchange in droplets",

abstract = "We present a method to first laterally position microparticles inside droplets by acoustic forces and then split the droplet into three daughter droplets to achieve a 2+fold enrichment of microparticles inside the center droplet. We show that acoustic forces can be applied to both manipulate polystyrene beads (5 μm) and red blood cells inside droplets. The presented technology opens up for development of droplet operations used for medium exchange and particle concentration in droplet-based cell assays.",

keywords = "Droplet microfluidics, Integrated acoustics, Ultrasound",

author = "Anna Fornell and Jonsson, \{H{\aa}kan N.\} and Johan Nilsson and Maria Tenje",

year = "2015",

language = "English",

pages = "1026--1028",

booktitle = "MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

publisher = "Chemical and Biological Microsystems Society",

note = "19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 ; Conference date: 25-10-2015 Through 29-10-2015",

}

Fornell, A, Jonsson, HN, Nilsson, J & Tenje, M 2015, Acoustic focusing of microparticles in two-phase systems - Towards cell enrichment or medium exchange in droplets. i MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, s. 1026-1028, 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015, Gyeongju, Sydkorea, Republiken Korea, 2015/10/25.

Acoustic focusing of microparticles in two-phase systems - Towards cell enrichment or medium exchange in droplets. / Fornell, Anna; Jonsson, Håkan N.; Nilsson, Johan et al.
MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2015. s. 1026-1028.

Forskningsoutput: Kapitel i bok/rapport/Conference proceeding › Konferenspaper i proceeding › Peer review

TY - GEN

T1 - Acoustic focusing of microparticles in two-phase systems - Towards cell enrichment or medium exchange in droplets

AU - Fornell, Anna

AU - Jonsson, Håkan N.

AU - Nilsson, Johan

AU - Tenje, Maria

PY - 2015

Y1 - 2015

N2 - We present a method to first laterally position microparticles inside droplets by acoustic forces and then split the droplet into three daughter droplets to achieve a 2+fold enrichment of microparticles inside the center droplet. We show that acoustic forces can be applied to both manipulate polystyrene beads (5 μm) and red blood cells inside droplets. The presented technology opens up for development of droplet operations used for medium exchange and particle concentration in droplet-based cell assays.

AB - We present a method to first laterally position microparticles inside droplets by acoustic forces and then split the droplet into three daughter droplets to achieve a 2+fold enrichment of microparticles inside the center droplet. We show that acoustic forces can be applied to both manipulate polystyrene beads (5 μm) and red blood cells inside droplets. The presented technology opens up for development of droplet operations used for medium exchange and particle concentration in droplet-based cell assays.

KW - Droplet microfluidics

KW - Integrated acoustics

KW - Ultrasound

UR - https://www.scopus.com/pages/publications/84983266550

M3 - Paper in conference proceeding

AN - SCOPUS:84983266550

SP - 1026

EP - 1028

BT - MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences

PB - Chemical and Biological Microsystems Society

T2 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015

Y2 - 25 October 2015 through 29 October 2015

ER -

Acoustic focusing of microparticles in two-phase systems - Towards cell enrichment or medium exchange in droplets

Sammanfattning

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Ämnesklassifikation (UKÄ)

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