An improved probing controller for substrate feeding in fed-batch culteres of E. coli: simulations and experiments

Mats Åkesson; Per Hagander; Jan Peter Axelsson

An improved probing controller for substrate feeding in fed-batch culteres of E. coli: simulations and experiments

Mats Åkesson, Per Hagander, Jan Peter Axelsson

Institutionen för reglerteknik

Forskningsoutput: Kapitel i bok/rapport/Conference proceeding › Konferenspaper i proceeding

Sammanfattning

A strategy for feedback control of the glucose feed rate in cultivations of E.coli is discussed. By making probing pulses in the feedrate it is possible to detect and avoid undesirable by-productformation using a standard dissolved oxygen sensor. The feasibility of an improved and simplified probing algorithm is demonstrated by simulations as well as laboratory-scale experiments.

Originalspråk	engelska
Titel på värdpublikation	Computer Applications in Biotechnology 2001
Förlag	Elsevier
Sidor	213-218
ISBN (tryckt)	0080436811
Status	Published - 2002
Evenemang	8th IFAC International Conference on Computer Applications in Biotechnology (CAB8) - Quebeq City, Kanada Varaktighet: 2001 juni 24 → 2001 juni 27

Konferens

Konferens	8th IFAC International Conference on Computer Applications in Biotechnology (CAB8)
Land/Territorium	Kanada
Ort	Quebeq City
Period	2001/06/24 → 2001/06/27

Ämnesklassifikation (UKÄ)

Reglerteknik

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@inproceedings{4edaf96b3832485f9cec60f80a23645c,

title = "An improved probing controller for substrate feeding in fed-batch culteres of E. coli: simulations and experiments",

abstract = "A strategy for feedback control of the glucose feed rate in cultivations of E.coli is discussed. By making probing pulses in the feedrate it is possible to detect and avoid undesirable by-productformation using a standard dissolved oxygen sensor. The feasibility of an improved and simplified probing algorithm is demonstrated by simulations as well as laboratory-scale experiments.",

keywords = "Fermentation process, probing, extremum control, process control",

author = "Mats {\AA}kesson and Per Hagander and Axelsson, \{Jan Peter\}",

year = "2002",

language = "English",

isbn = "0080436811",

pages = "213--218",

booktitle = "Computer Applications in Biotechnology 2001",

publisher = "Elsevier",

address = "United States",

note = "8th IFAC International Conference on Computer Applications in Biotechnology (CAB8) ; Conference date: 24-06-2001 Through 27-06-2001",

}

TY - GEN

T1 - An improved probing controller for substrate feeding in fed-batch culteres of E. coli: simulations and experiments

AU - Åkesson, Mats

AU - Hagander, Per

AU - Axelsson, Jan Peter

PY - 2002

Y1 - 2002

N2 - A strategy for feedback control of the glucose feed rate in cultivations of E.coli is discussed. By making probing pulses in the feedrate it is possible to detect and avoid undesirable by-productformation using a standard dissolved oxygen sensor. The feasibility of an improved and simplified probing algorithm is demonstrated by simulations as well as laboratory-scale experiments.

AB - A strategy for feedback control of the glucose feed rate in cultivations of E.coli is discussed. By making probing pulses in the feedrate it is possible to detect and avoid undesirable by-productformation using a standard dissolved oxygen sensor. The feasibility of an improved and simplified probing algorithm is demonstrated by simulations as well as laboratory-scale experiments.

KW - Fermentation process

KW - probing

KW - extremum control

KW - process control

M3 - Paper in conference proceeding

SN - 0080436811

SP - 213

EP - 218

BT - Computer Applications in Biotechnology 2001

PB - Elsevier

T2 - 8th IFAC International Conference on Computer Applications in Biotechnology (CAB8)

Y2 - 24 June 2001 through 27 June 2001

ER -

An improved probing controller for substrate feeding in fed-batch culteres of E. coli: simulations and experiments

Sammanfattning

Konferens

Ämnesklassifikation (UKÄ)

Fingeravtryck

Citera det här