Antisense RNAs everywhere?

E.G.H. Wagner, Klas Flärdh

Forskningsoutput: TidskriftsbidragÖversiktsartikelPeer review

Sammanfattning

In recent years, systematic searches of both prokaryote and eukaryote genomes have identified a staggering number of small RNAs, the biological functions of which remain unknown. Small RNA-based regulators are well known from bacterial plasmids. They act on target RNAs by sequence complementarity; that is, they are antisense RNAs. Recent findings suggest that many of the novel orphan RNAs encoded by bacterial and eukaryotic chromosomes might also belong to a ubiquitous, heterogeneous class of antisense regulators of gene expression.
Originalspråkengelska
Sidor (från-till)223-226
TidskriftTrends in Genetics
Volym18
Nummer5
DOI
StatusPublished - 2002
Externt publiceradJa

Ämnesklassifikation (UKÄ)

  • Biologiska vetenskaper

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