Association between the EAT-Lancet Diet, Incidence of Cardiovascular Events, and All-cause Mortality: Results from a Swiss Cohort

Laís Bhering Martins, Magda Gamba, Anna Stubbendorff, Nathalie Gasser, Laura Löbl, Florian Stern, Ulrika Ericson, Pedro Marques-Vidal, Séverine Vuilleumier, Angeline Chatelan

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

Sammanfattning

BACKGROUND: An unhealthy diet is a major contributor to several noncommunicable diseases, including cardiovascular diseases (CVD), the leading cause of death worldwide. Additionally, our food system has significant impacts on the environment. The EAT-Lancet Commission has recommended a healthy diet that preserves global environmental resources.

OBJECTIVE: This prospective study evaluated the associations between adherence to the EAT-Lancet diet and the incidence of cardiovascular events and all-cause mortality in a Swiss cohort.

METHODS: We analyzed data from the CoLaus|PsyCoLaus cohort study (n = 3,866). Dietary intake was assessed using a semiquantitative food frequency questionnaire. The EAT-Lancet adherence score was calculated based on the recommended intake and reference intervals of 12 food components, ranging from 0 to 39 points. Participants were categorized into low-, medium-, and high-adherence groups according to score tertiles. We used Cox Proportional Hazards regressions to assess the association between diet adherence, incident cardiovascular events and all-cause mortality.

RESULTS: During a mean follow-up of 7.9 years (SD, ±2.0), 294 individuals (7.6%) from our initial sample experienced a first cardiovascular event, and 264 (6.8%) died. Compared with the low-adherence group, the adjusted hazard ratios for all-cause mortality were 0.88 (95% CI: 0.66-1.17) and 0.70 (95% CI: 0.49-0.98) for the medium- and high-adherence groups, respectively (p for trend = 0.04). We observed no association between adherence groups and cardiovascular events.

CONCLUSIONS: In a Swiss cohort, high adherence to the EAT-Lancet diet was associated with a potential 30% lower risk of overall mortality. However, no association was found between the EAT-Lancet diet and cardiovascular events.

Originalspråkengelska
TidskriftThe Journal of nutrition
DOI
StatusE-pub ahead of print - 2024 dec. 30

Bibliografisk information

Copyright © 2024. Published by Elsevier Inc.

Ämnesklassifikation (UKÄ)

  • Endokrinologi och diabetes
  • Kardiologi

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