TY - JOUR
T1 - Association between the EAT-Lancet Diet, Incidence of Cardiovascular Events, and All-cause Mortality
T2 - Results from a Swiss Cohort
AU - Martins, Laís Bhering
AU - Gamba, Magda
AU - Stubbendorff, Anna
AU - Gasser, Nathalie
AU - Löbl, Laura
AU - Stern, Florian
AU - Ericson, Ulrika
AU - Marques-Vidal, Pedro
AU - Vuilleumier, Séverine
AU - Chatelan, Angeline
N1 - Copyright © 2024. Published by Elsevier Inc.
PY - 2024/12/30
Y1 - 2024/12/30
N2 - BACKGROUND: An unhealthy diet is a major contributor to several noncommunicable diseases, including cardiovascular diseases (CVD), the leading cause of death worldwide. Additionally, our food system has significant impacts on the environment. The EAT-Lancet Commission has recommended a healthy diet that preserves global environmental resources.OBJECTIVE: This prospective study evaluated the associations between adherence to the EAT-Lancet diet and the incidence of cardiovascular events and all-cause mortality in a Swiss cohort.METHODS: We analyzed data from the CoLaus|PsyCoLaus cohort study (n = 3,866). Dietary intake was assessed using a semiquantitative food frequency questionnaire. The EAT-Lancet adherence score was calculated based on the recommended intake and reference intervals of 12 food components, ranging from 0 to 39 points. Participants were categorized into low-, medium-, and high-adherence groups according to score tertiles. We used Cox Proportional Hazards regressions to assess the association between diet adherence, incident cardiovascular events and all-cause mortality.RESULTS: During a mean follow-up of 7.9 years (SD, ±2.0), 294 individuals (7.6%) from our initial sample experienced a first cardiovascular event, and 264 (6.8%) died. Compared with the low-adherence group, the adjusted hazard ratios for all-cause mortality were 0.88 (95% CI: 0.66-1.17) and 0.70 (95% CI: 0.49-0.98) for the medium- and high-adherence groups, respectively (p for trend = 0.04). We observed no association between adherence groups and cardiovascular events.CONCLUSIONS: In a Swiss cohort, high adherence to the EAT-Lancet diet was associated with a potential 30% lower risk of overall mortality. However, no association was found between the EAT-Lancet diet and cardiovascular events.
AB - BACKGROUND: An unhealthy diet is a major contributor to several noncommunicable diseases, including cardiovascular diseases (CVD), the leading cause of death worldwide. Additionally, our food system has significant impacts on the environment. The EAT-Lancet Commission has recommended a healthy diet that preserves global environmental resources.OBJECTIVE: This prospective study evaluated the associations between adherence to the EAT-Lancet diet and the incidence of cardiovascular events and all-cause mortality in a Swiss cohort.METHODS: We analyzed data from the CoLaus|PsyCoLaus cohort study (n = 3,866). Dietary intake was assessed using a semiquantitative food frequency questionnaire. The EAT-Lancet adherence score was calculated based on the recommended intake and reference intervals of 12 food components, ranging from 0 to 39 points. Participants were categorized into low-, medium-, and high-adherence groups according to score tertiles. We used Cox Proportional Hazards regressions to assess the association between diet adherence, incident cardiovascular events and all-cause mortality.RESULTS: During a mean follow-up of 7.9 years (SD, ±2.0), 294 individuals (7.6%) from our initial sample experienced a first cardiovascular event, and 264 (6.8%) died. Compared with the low-adherence group, the adjusted hazard ratios for all-cause mortality were 0.88 (95% CI: 0.66-1.17) and 0.70 (95% CI: 0.49-0.98) for the medium- and high-adherence groups, respectively (p for trend = 0.04). We observed no association between adherence groups and cardiovascular events.CONCLUSIONS: In a Swiss cohort, high adherence to the EAT-Lancet diet was associated with a potential 30% lower risk of overall mortality. However, no association was found between the EAT-Lancet diet and cardiovascular events.
U2 - 10.1016/j.tjnut.2024.12.012
DO - 10.1016/j.tjnut.2024.12.012
M3 - Article
C2 - 39742968
SN - 1541-6100
JO - The Journal of nutrition
JF - The Journal of nutrition
ER -