Bases moleculares e importancia clínica de los excepcionales fenotipos de grupo sanguíneo P y PK

Daniel De La Vega Elena; Asa Hellberg; Mario Pivetta; Miguel Ángel Raillon; Sergio Chialina; E. Solis; Martin L Olsson

Bases moleculares e importancia clínica de los excepcionales fenotipos de grupo sanguíneo P y P^K

Daniel De La Vega Elena, Asa Hellberg, Mario Pivetta, Miguel Ángel Raillon, Sergio Chialina, E. Solis, Martin L Olsson

Forskningsoutput: Tidskriftsbidrag › Översiktsartikel › Peer review

Sammanfattning

All the cells of the individuals with phenotypes "p" y "Pk" lack the glucidic antigens of "public" blood groups. These subjects form natural and regular antibodies against the missing structures (anti-P, anti-PP1 y anti-PP1Pk) that agglutínate or hemolyze the red-blood cells of every individual, excepting those with the same phenotype. Due to the exceptional character of these pictures (a few individuals per million) and their association with severe transfusional hemolytic reactions and repeated miscarriages, these subjects should be identified and characterized.

Bidragets översatta titel	Molecular bases and clinical importance of the exceptional phenotypes of blood group P and PK
Originalspråk	spanska
Tidskrift	Revista Cubana de Hematologia, Inmunologia y Hemoterapia
Volym	24
Nummer	3
Status	Published - 2008 sep.

Bibliografisk information

Copyright:
Copyright 2009 Elsevier B.V., All rights reserved.

Ämnesklassifikation (UKÄ)

Hematologi
Immunologi inom det medicinska området

Tillgång till dokument

http://scielo.sld.cu/pdf/hih/v24n3/hih02308.pdf

Citera det här

@article{dfee3bf2666c4f0f88859e840765c84f,

title = "Bases moleculares e importancia cl{\'i}nica de los excepcionales fenotipos de grupo sangu{\'i}neo P y PK",

abstract = "All the cells of the individuals with phenotypes {"}p{"} y {"}Pk{"} lack the glucidic antigens of {"}public{"} blood groups. These subjects form natural and regular antibodies against the missing structures (anti-P, anti-PP1 y anti-PP1Pk) that agglut{\'i}nate or hemolyze the red-blood cells of every individual, excepting those with the same phenotype. Due to the exceptional character of these pictures (a few individuals per million) and their association with severe transfusional hemolytic reactions and repeated miscarriages, these subjects should be identified and characterized.",

keywords = "Alloimmunization, Blood group, Erythrocyte, Gestation, Glycosyltransferases, Transfusion",

author = "Elena, {Daniel De La Vega} and Asa Hellberg and Mario Pivetta and Raillon, {Miguel {\'A}ngel} and Sergio Chialina and E. Solis and Olsson, {Martin L}",

year = "2008",

month = sep,

language = "spanska",

volume = "24",

journal = "Revista Cubana de Hematologia, Inmunologia y Hemoterapia",

issn = "0864-0289",

publisher = "Editorial Ciencias Medicas",

number = "3",

}

TY - JOUR

T1 - Bases moleculares e importancia clínica de los excepcionales fenotipos de grupo sanguíneo P y PK

AU - Elena, Daniel De La Vega

AU - Hellberg, Asa

AU - Pivetta, Mario

AU - Raillon, Miguel Ángel

AU - Chialina, Sergio

AU - Solis, E.

AU - Olsson, Martin L

PY - 2008/9

Y1 - 2008/9

N2 - All the cells of the individuals with phenotypes "p" y "Pk" lack the glucidic antigens of "public" blood groups. These subjects form natural and regular antibodies against the missing structures (anti-P, anti-PP1 y anti-PP1Pk) that agglutínate or hemolyze the red-blood cells of every individual, excepting those with the same phenotype. Due to the exceptional character of these pictures (a few individuals per million) and their association with severe transfusional hemolytic reactions and repeated miscarriages, these subjects should be identified and characterized.

AB - All the cells of the individuals with phenotypes "p" y "Pk" lack the glucidic antigens of "public" blood groups. These subjects form natural and regular antibodies against the missing structures (anti-P, anti-PP1 y anti-PP1Pk) that agglutínate or hemolyze the red-blood cells of every individual, excepting those with the same phenotype. Due to the exceptional character of these pictures (a few individuals per million) and their association with severe transfusional hemolytic reactions and repeated miscarriages, these subjects should be identified and characterized.

KW - Alloimmunization

KW - Blood group

KW - Erythrocyte

KW - Gestation

KW - Glycosyltransferases

KW - Transfusion

M3 - Översiktsartikel

AN - SCOPUS:67649948944

SN - 0864-0289

VL - 24

JO - Revista Cubana de Hematologia, Inmunologia y Hemoterapia

JF - Revista Cubana de Hematologia, Inmunologia y Hemoterapia

IS - 3

ER -