Blueberry husks and multi-strain probiotics affect colonic fermentation in rats.

Camilla Bränning; Åsa Håkansson; Siv Ahrné; Bengt Jeppsson; Göran Molin; Margareta Nyman

doi:10.1017/S0007114508047703

Blueberry husks and multi-strain probiotics affect colonic fermentation in rats.

Camilla Bränning, Åsa Håkansson, Siv Ahrné, Bengt Jeppsson, Göran Molin, Margareta Nyman

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

Sammanfattning

The aim was to investigate how blueberry husks and/or mixtures of probiotic strains (Lactobacillus crispatus DSM16743, L. gasseri DSM16737 and L. plantarum DSM15313 (LABmix), or Bifidobacterium infantis DSM15159 and DSM15161 (BIFmix)) affect colonic fermentation, caecal counts of lactobacilli, bifidobacteria and Enterobacteriaceae, body weight gain, and blood concentrations of carboxylic acids (CA) and ammonia in rats. Dietary fibres in blueberry husks were fermented to 61 % in colon, and the elevated faecal excretion of fibre and protein contributed to the high faecal bulking capacity (1.3). The caecal pool of CA was higher in rats fed blueberry husks than the fibre-free control (P < 0.05), and the propionic acid proportion was higher in the distal colon than in the control group (P < 0.05). Probiotics lowered the caecal amount of CA when added to blueberry husks (P < 0.001), while the propionic acid proportion was higher with LABmix (P < 0.01) than blueberry husks only. The propionic acid and butyric acid concentrations in blood were higher in rats fed blueberry husks and probiotics than those fed blueberry husks only (P < 0.01), implying that the absorption of these acids was facilitated by the bacteria. The caecal counts of lactobacilli, bifidobacteria and Enterobacteriaceae were lower in rats fed blueberry husks than the control diet (P < 0.05). The body weight gain was partly influenced by the caecal tissue and contents weights, and BIFmix decreased the ammonia concentration in blood (P < 0.05). We conclude that colonic fermentation is differentially affected by dietary fibre and probiotics, which may be of importance when developing foods with certain health effects.

Originalspråk	engelska
Sidor (från-till)	859-870
Tidskrift	British Journal of Nutrition
Volym	100
Nummer	1
DOI	https://doi.org/10.1017/S0007114508047703
Status	Published - 2009

Bibliografisk information

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Applied Nutrition and Food Chemistry (011001300), Surgery Research Unit (013242220)

Ämnesklassifikation (UKÄ)

Näringslära och dietkunskap

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10.1017/S0007114508047703

AFC: ANTIDIABETIC FOOD CENTRE
Adlercreutz, P. (PI), Ahrén, I. L. (PI), Ahrné, S. (Forskare), Alhamimi, S. (Forskarstuderande), Andersson, K. E. (Forskare), Andersson, K. E. (Forskarstuderande), Månberger, A. (Forskare), Axling, U. (Forskare), Axling, U. (Forskarstuderande), Bergenståhl, B. (Forskare), Berger, K. (PI), Björck, I. (PI), Bränning, C. (Forskarstuderande), Bäckhed, F. (PI), Zanzer, Y. C. (Forskarstuderande), Danielsson, A. (PI), Danielsson, B. (Forskningsassistent), Degerman, E. (PI), Dejmek, P. (Forskare), Dey, E. (PI), Dougkas, A. (Forskare), Ekström, L. (Forskarstuderande), Eliasson, A.-C. (PI), Fahlgren, C. (Forskningsingenjör), Falck, P. (PI), Falck, P. (Forskarstuderande), Ghaffarzadegan, T. (Forskarstuderande), Granfeldt, Y. (Forskare), Grey, C. (Forskare), Gunnerud, U. (Forskarstuderande), Håkansson, Å. (Forskare), Håkansson, Å. (Forskarstuderande), Hållenius, F. (Forskare), Hållenius, F. (PI), Haskå, L. (PI), Haskå, L. (Forskarstuderande), Heimann, E. (Forskarstuderande), Hellstrand, P. (Forskare), Heyman, L. (Forskarstuderande), Holm Wallenberg, C. (PI), Holmén-Pålbrink, A.-K. (Forskningsassistent), Holst, O. (Forskare), Immerstrand, T. (Forskarstuderande), Immerzeel, P. (Forskare), Jakobsdottir, G. (Forskarstuderande), Jeppsson, B. (Forskare), Johansson, E. (Forskarstuderande), Johansson, M. (Projektkoordinator), Johansson, M. (Forskare), Johansson, M. (Forskningsassistent), Johansson, U. (Forskare), Jones, H. (Forskare), Nordberg Karlsson, E. (Forskare), Kovatcheva-Datchary, P. (Forskare), Kulcinskaja, E. (Forskarstuderande), Landin-Olsson, M. (Forskare), Linninge, C. (Forskare), Marefati, A. (Forskarstuderande), Marungruang, N. (Forskarstuderande), Molin, G. (PI), Nilsson, A. (PI), Nilsson, E. (Forskningsingenjör), Nilsson, U. (PI), Nyman, M. (PI), Ohlson, E. (Forskningsassistent), Olsson, C. (Forskare), Öste, R. (PI), Östman, E. (PI), Persson, L. (Forskningsingenjör), Persson, S. (Forskare), Plaza, M. (Forskare), Prykhodko, O. (Forskare), Radeborg, K. (Forskare), Rayner, M. (PI), Rosén, L. (Forskarstuderande), Sandahl, M. (Forskare), Sandberg, J. (Forskarstuderande), Sjöö, M. (PI), Skog, K. (Forskare), Spégel, P. (PI), Stålbrand, H. (Forskare), Sterner, O. (PI), Svensson, J. (Forskarstuderande), Tareke, E. (PI), Tovar, J. (PI), Turner, C. (PI), Weström, B. (Forskare), Xu, J. (Forskarstuderande) & Zhong, Y. (Forskarstuderande)
2007/07/01 → 2018/01/31
Projekt: Forskning

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@article{4ac480467f4e4c5eabd34f7248eb4851,

title = "Blueberry husks and multi-strain probiotics affect colonic fermentation in rats.",

abstract = "The aim was to investigate how blueberry husks and/or mixtures of probiotic strains (Lactobacillus crispatus DSM16743, L. gasseri DSM16737 and L. plantarum DSM15313 (LABmix), or Bifidobacterium infantis DSM15159 and DSM15161 (BIFmix)) affect colonic fermentation, caecal counts of lactobacilli, bifidobacteria and Enterobacteriaceae, body weight gain, and blood concentrations of carboxylic acids (CA) and ammonia in rats. Dietary fibres in blueberry husks were fermented to 61 % in colon, and the elevated faecal excretion of fibre and protein contributed to the high faecal bulking capacity (1.3). The caecal pool of CA was higher in rats fed blueberry husks than the fibre-free control (P < 0.05), and the propionic acid proportion was higher in the distal colon than in the control group (P < 0.05). Probiotics lowered the caecal amount of CA when added to blueberry husks (P < 0.001), while the propionic acid proportion was higher with LABmix (P < 0.01) than blueberry husks only. The propionic acid and butyric acid concentrations in blood were higher in rats fed blueberry husks and probiotics than those fed blueberry husks only (P < 0.01), implying that the absorption of these acids was facilitated by the bacteria. The caecal counts of lactobacilli, bifidobacteria and Enterobacteriaceae were lower in rats fed blueberry husks than the control diet (P < 0.05). The body weight gain was partly influenced by the caecal tissue and contents weights, and BIFmix decreased the ammonia concentration in blood (P < 0.05). We conclude that colonic fermentation is differentially affected by dietary fibre and probiotics, which may be of importance when developing foods with certain health effects.",

keywords = "Weight gain, Carboxylic acids, Ammonia, Short-chain fatty acids, Lactobacillus gasseri, Lactobacillus plantarum, Lactobacillus crispatus, Bifidobacterium infantis, Probiotics, Dietary fibre, Blueberry husks",

author = "Camilla Br{\"a}nning and {\AA}sa H{\aa}kansson and Siv Ahrn{\'e} and Bengt Jeppsson and G{\"o}ran Molin and Margareta Nyman",

note = "The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Applied Nutrition and Food Chemistry (011001300), Surgery Research Unit (013242220)",

year = "2009",

doi = "10.1017/S0007114508047703",

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volume = "100",

pages = "859--870",

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T1 - Blueberry husks and multi-strain probiotics affect colonic fermentation in rats.

AU - Bränning, Camilla

AU - Håkansson, Åsa

AU - Ahrné, Siv

AU - Jeppsson, Bengt

AU - Molin, Göran

AU - Nyman, Margareta

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Applied Nutrition and Food Chemistry (011001300), Surgery Research Unit (013242220)

PY - 2009

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N2 - The aim was to investigate how blueberry husks and/or mixtures of probiotic strains (Lactobacillus crispatus DSM16743, L. gasseri DSM16737 and L. plantarum DSM15313 (LABmix), or Bifidobacterium infantis DSM15159 and DSM15161 (BIFmix)) affect colonic fermentation, caecal counts of lactobacilli, bifidobacteria and Enterobacteriaceae, body weight gain, and blood concentrations of carboxylic acids (CA) and ammonia in rats. Dietary fibres in blueberry husks were fermented to 61 % in colon, and the elevated faecal excretion of fibre and protein contributed to the high faecal bulking capacity (1.3). The caecal pool of CA was higher in rats fed blueberry husks than the fibre-free control (P < 0.05), and the propionic acid proportion was higher in the distal colon than in the control group (P < 0.05). Probiotics lowered the caecal amount of CA when added to blueberry husks (P < 0.001), while the propionic acid proportion was higher with LABmix (P < 0.01) than blueberry husks only. The propionic acid and butyric acid concentrations in blood were higher in rats fed blueberry husks and probiotics than those fed blueberry husks only (P < 0.01), implying that the absorption of these acids was facilitated by the bacteria. The caecal counts of lactobacilli, bifidobacteria and Enterobacteriaceae were lower in rats fed blueberry husks than the control diet (P < 0.05). The body weight gain was partly influenced by the caecal tissue and contents weights, and BIFmix decreased the ammonia concentration in blood (P < 0.05). We conclude that colonic fermentation is differentially affected by dietary fibre and probiotics, which may be of importance when developing foods with certain health effects.

AB - The aim was to investigate how blueberry husks and/or mixtures of probiotic strains (Lactobacillus crispatus DSM16743, L. gasseri DSM16737 and L. plantarum DSM15313 (LABmix), or Bifidobacterium infantis DSM15159 and DSM15161 (BIFmix)) affect colonic fermentation, caecal counts of lactobacilli, bifidobacteria and Enterobacteriaceae, body weight gain, and blood concentrations of carboxylic acids (CA) and ammonia in rats. Dietary fibres in blueberry husks were fermented to 61 % in colon, and the elevated faecal excretion of fibre and protein contributed to the high faecal bulking capacity (1.3). The caecal pool of CA was higher in rats fed blueberry husks than the fibre-free control (P < 0.05), and the propionic acid proportion was higher in the distal colon than in the control group (P < 0.05). Probiotics lowered the caecal amount of CA when added to blueberry husks (P < 0.001), while the propionic acid proportion was higher with LABmix (P < 0.01) than blueberry husks only. The propionic acid and butyric acid concentrations in blood were higher in rats fed blueberry husks and probiotics than those fed blueberry husks only (P < 0.01), implying that the absorption of these acids was facilitated by the bacteria. The caecal counts of lactobacilli, bifidobacteria and Enterobacteriaceae were lower in rats fed blueberry husks than the control diet (P < 0.05). The body weight gain was partly influenced by the caecal tissue and contents weights, and BIFmix decreased the ammonia concentration in blood (P < 0.05). We conclude that colonic fermentation is differentially affected by dietary fibre and probiotics, which may be of importance when developing foods with certain health effects.

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KW - Carboxylic acids

KW - Ammonia

KW - Short-chain fatty acids

KW - Lactobacillus gasseri

KW - Lactobacillus plantarum

KW - Lactobacillus crispatus

KW - Bifidobacterium infantis

KW - Probiotics

KW - Dietary fibre

KW - Blueberry husks

U2 - 10.1017/S0007114508047703

DO - 10.1017/S0007114508047703

M3 - Article

C2 - 18680631

SN - 1475-2662

VL - 100

SP - 859

EP - 870

JO - British Journal of Nutrition

JF - British Journal of Nutrition

IS - 1

ER -

Blueberry husks and multi-strain probiotics affect colonic fermentation in rats.

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