Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.

Rasmus W Green; Sanna Engblom; Bo Baldetorp; Linda Werner Hartman; Anna Måsbäck; Maria Bjurberg

doi:10.1111/aogs.12704

Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.

Rasmus W Green, Sanna Engblom, Bo Baldetorp, Linda Werner Hartman, Anna Måsbäck, Maria Bjurberg

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

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Sammanfattning

In early-stage endometrial carcinoma, there is controversy regarding the prognostic value of the flow cytometric variables DNA ploidy (diploid vs. aneuploid) and S-phase fraction. In Sweden, the former is included in national guidelines despite poor scientific support and the latter is not used clinically. This study investigates the prognostic properties of these variables, together with classical histopathological variables, in multivariate analysis in a stringently stratified material.

Originalspråk	engelska
Sidor (från-till)	1064-1073
Tidskrift	Acta Obstetricia et Gynecologica Scandinavica
Volym	94
Nummer	10
DOI	https://doi.org/10.1111/aogs.12704
Status	Published - 2015

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SDG 3 – God hälsa och välbefinnande

Ämnesklassifikation (UKÄ)

Cancer och onkologi

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10.1111/aogs.12704

Wiley-Blackwell_Green_et_al

http://www.ncbi.nlm.nih.gov/pubmed/26123703?dopt=Abstract

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Green, R. W., Engblom, S., Baldetorp, B., Werner Hartman, L., Måsbäck, A., & Bjurberg, M. (2015). Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study. Acta Obstetricia et Gynecologica Scandinavica, 94(10), 1064-1073. https://doi.org/10.1111/aogs.12704

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title = "Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.",

abstract = "In early-stage endometrial carcinoma, there is controversy regarding the prognostic value of the flow cytometric variables DNA ploidy (diploid vs. aneuploid) and S-phase fraction. In Sweden, the former is included in national guidelines despite poor scientific support and the latter is not used clinically. This study investigates the prognostic properties of these variables, together with classical histopathological variables, in multivariate analysis in a stringently stratified material.",

author = "Green, \{Rasmus W\} and Sanna Engblom and Bo Baldetorp and \{Werner Hartman\}, Linda and Anna M{\aa}sb{\"a}ck and Maria Bjurberg",

year = "2015",

doi = "10.1111/aogs.12704",

language = "English",

volume = "94",

pages = "1064--1073",

journal = "Acta Obstetricia et Gynecologica Scandinavica",

issn = "1600-0412",

publisher = "Wiley-Blackwell",

number = "10",

}

Green, RW, Engblom, S, Baldetorp, B , Werner Hartman, L, Måsbäck, A & Bjurberg, M 2015, 'Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.', Acta Obstetricia et Gynecologica Scandinavica, vol. 94, nr. 10, s. 1064-1073. https://doi.org/10.1111/aogs.12704

Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study. / Green, Rasmus W; Engblom, Sanna; Baldetorp, Bo et al.
I: Acta Obstetricia et Gynecologica Scandinavica, Vol. 94, Nr. 10, 2015, s. 1064-1073.

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

TY - JOUR

T1 - Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.

AU - Green, Rasmus W

AU - Engblom, Sanna

AU - Baldetorp, Bo

AU - Werner Hartman, Linda

AU - Måsbäck, Anna

AU - Bjurberg, Maria

PY - 2015

Y1 - 2015

N2 - In early-stage endometrial carcinoma, there is controversy regarding the prognostic value of the flow cytometric variables DNA ploidy (diploid vs. aneuploid) and S-phase fraction. In Sweden, the former is included in national guidelines despite poor scientific support and the latter is not used clinically. This study investigates the prognostic properties of these variables, together with classical histopathological variables, in multivariate analysis in a stringently stratified material.

AB - In early-stage endometrial carcinoma, there is controversy regarding the prognostic value of the flow cytometric variables DNA ploidy (diploid vs. aneuploid) and S-phase fraction. In Sweden, the former is included in national guidelines despite poor scientific support and the latter is not used clinically. This study investigates the prognostic properties of these variables, together with classical histopathological variables, in multivariate analysis in a stringently stratified material.

UR - https://www.scopus.com/pages/publications/84941660184

U2 - 10.1111/aogs.12704

DO - 10.1111/aogs.12704

M3 - Article

C2 - 26123703

SN - 1600-0412

VL - 94

SP - 1064

EP - 1073

JO - Acta Obstetricia et Gynecologica Scandinavica

JF - Acta Obstetricia et Gynecologica Scandinavica

IS - 10

ER -

Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.

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