Characterization of Stimulus-Secretion Coupling in the Human Pancreatic EndoC-βH1 Beta Cell Line.

Lotta Andersson, Berengere Valtat, Annika Bagge, Vladimir Sharoyko, David Nicholls, Philippe Ravassard, Raphael Scharfmann, Peter Spégel, Hindrik Mulder

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

50 Citeringar (SciVal)
216 Nedladdningar (Pure)

Sammanfattning

Studies on beta cell metabolism are often conducted in rodent beta cell lines due to the lack of stable human beta cell lines. Recently, a human cell line, EndoC-βH1, was generated. Here we investigate stimulus-secretion coupling in this cell line, and compare it with that in the rat beta cell line, INS-1 832/13, and human islets.
Originalspråkengelska
Artikelnummere0120879
TidskriftPLoS ONE
Volym10
Utgåva3
DOI
StatusPublished - 2015

Ämnesklassifikation (UKÄ)

  • Endokrinologi och diabetes

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