Characterization of Stimulus-Secretion Coupling in the Human Pancreatic EndoC-βH1 Beta Cell Line.

Lotta Andersson; Berengere Valtat; Annika Bagge; Vladimir Sharoyko; David Nicholls; Philippe Ravassard; Raphael Scharfmann; Peter Spégel; Hindrik Mulder

doi:10.1371/journal.pone.0120879

Characterization of Stimulus-Secretion Coupling in the Human Pancreatic EndoC-βH1 Beta Cell Line.

Lotta Andersson, Berengere Valtat, Annika Bagge, Vladimir Sharoyko, David Nicholls, Philippe Ravassard, Raphael Scharfmann, Peter Spégel, Hindrik Mulder

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

50 Citeringar (SciVal)

216 Nedladdningar (Pure)

Sammanfattning

Studies on beta cell metabolism are often conducted in rodent beta cell lines due to the lack of stable human beta cell lines. Recently, a human cell line, EndoC-βH1, was generated. Here we investigate stimulus-secretion coupling in this cell line, and compare it with that in the rat beta cell line, INS-1 832/13, and human islets.

Originalspråk	engelska
Artikelnummer	e0120879
Tidskrift	PLoS ONE
Volym	10
Utgåva	3
DOI	https://doi.org/10.1371/journal.pone.0120879
Status	Published - 2015

Ämnesklassifikation (UKÄ)

Endokrinologi och diabetes

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10.1371/journal.pone.0120879

Plos_Andersson_et_al

http://www.ncbi.nlm.nih.gov/pubmed/25803449?dopt=Abstract

50 Citeringar
1 Doktorsavhandling (sammanläggning)

Stimulus-Section Coupling in Endocrine Cell Models
Andersson, L., 2015, Department of Clinical Sciences, Lund University. 58 s.
Forskningsoutput: Avhandling › Doktorsavhandling (sammanläggning)

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title = "Characterization of Stimulus-Secretion Coupling in the Human Pancreatic EndoC-βH1 Beta Cell Line.",

abstract = "Studies on beta cell metabolism are often conducted in rodent beta cell lines due to the lack of stable human beta cell lines. Recently, a human cell line, EndoC-βH1, was generated. Here we investigate stimulus-secretion coupling in this cell line, and compare it with that in the rat beta cell line, INS-1 832/13, and human islets.",

author = "Lotta Andersson and Berengere Valtat and Annika Bagge and Vladimir Sharoyko and David Nicholls and Philippe Ravassard and Raphael Scharfmann and Peter Sp{\'e}gel and Hindrik Mulder",

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doi = "10.1371/journal.pone.0120879",

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volume = "10",

journal = "PLoS ONE",

issn = "1932-6203",

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Characterization of Stimulus-Secretion Coupling in the Human Pancreatic EndoC-βH1 Beta Cell Line. / Andersson, Lotta; Valtat, Berengere; Bagge, Annika; Sharoyko, Vladimir; Nicholls, David; Ravassard, Philippe; Scharfmann, Raphael; Spégel, Peter ; Mulder, Hindrik.

I: PLoS ONE, Vol. 10, Nr. 3, e0120879, 2015.

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

TY - JOUR

T1 - Characterization of Stimulus-Secretion Coupling in the Human Pancreatic EndoC-βH1 Beta Cell Line.

AU - Andersson, Lotta

AU - Valtat, Berengere

AU - Bagge, Annika

AU - Sharoyko, Vladimir

AU - Nicholls, David

AU - Ravassard, Philippe

AU - Scharfmann, Raphael

AU - Spégel, Peter

AU - Mulder, Hindrik

PY - 2015

Y1 - 2015

N2 - Studies on beta cell metabolism are often conducted in rodent beta cell lines due to the lack of stable human beta cell lines. Recently, a human cell line, EndoC-βH1, was generated. Here we investigate stimulus-secretion coupling in this cell line, and compare it with that in the rat beta cell line, INS-1 832/13, and human islets.

AB - Studies on beta cell metabolism are often conducted in rodent beta cell lines due to the lack of stable human beta cell lines. Recently, a human cell line, EndoC-βH1, was generated. Here we investigate stimulus-secretion coupling in this cell line, and compare it with that in the rat beta cell line, INS-1 832/13, and human islets.

U2 - 10.1371/journal.pone.0120879

DO - 10.1371/journal.pone.0120879

M3 - Article

C2 - 25803449

VL - 10

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 3

M1 - e0120879

ER -

Characterization of Stimulus-Secretion Coupling in the Human Pancreatic EndoC-βH1 Beta Cell Line.

Sammanfattning

Ämnesklassifikation (UKÄ)

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Forskningsoutput

Stimulus-Section Coupling in Endocrine Cell Models

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