Sammanfattning

Hepatocyte growth factor (HGF) is released by stressed human vascular cells and promotes vascular cell repair responses in both autocrine and paracrine ways. Subjects with a low capacity to express HGF in response to systemic stress have an increased cardiovascular risk. Human atherosclerotic plaques with a low content of HGF have a more unstable phenotype. The present study shows that subjects with a low ability to express HGF in response to metabolic stress have an increased risk to suffer myocardial infarction and stroke.
Originalspråkengelska
Sidor (från-till)747-762
TidskriftJACC: Basic to Translational Science
Volym7
Nummer8
Tidigt onlinedatum2022
DOI
StatusPublished - 2022

Ämnesklassifikation (UKÄ)

  • Kardiologi

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