TY - JOUR
T1 - Coffee and tea consumption and the risk of ovarian cancer: a prospective cohort study and updated meta-analysis
AU - Braem, Marieke G. M.
AU - Onland-Moret, N. Charlotte
AU - Schouten, Leo J.
AU - Tjonneland, Anne
AU - Hansen, Louise
AU - Dahm, Christina C.
AU - Overvad, Kim
AU - Lukanova, Annekatrin
AU - Dossus, Laure
AU - Floegel, Anna
AU - Boeing, Heiner
AU - Clavel-Chapelon, Francoise
AU - Chabbert-Buffet, Nathalie
AU - Fagherazzi, Guy
AU - Trichopoulou, Antonia
AU - Benetou, Vassiliki
AU - Goufa, Ioulia
AU - Pala, Valeria
AU - Galasso, Rocco
AU - Mattiello, Amalia
AU - Sacerdote, Carlotta
AU - Palli, Domenico
AU - Tumino, Rosario
AU - Gram, Inger T.
AU - Lund, Eiliv
AU - Gavrilyuk, Oxana
AU - Sanchez, Maria-Jose
AU - Quiros, Ramon
AU - Gonzales, Carlos A.
AU - Dorronsoro, Miren
AU - Huerta Castano, Jose M.
AU - Barricarte Gurrea, Aurelio
AU - Idahl, Annika
AU - Ohlson, Nina
AU - Lundin, Eva
AU - Jirström, Karin
AU - Wirfält, Elisabet
AU - Allen, Naomi E.
AU - Tsilidis, Konstantinos K.
AU - Kaw, Kay-Tee
AU - Bueno-de-Mesquita, H. Bas
AU - Dik, Vincent K.
AU - Rinaldi, Sabina
AU - Fedirko, Veronika
AU - Norat, Teresa
AU - Riboli, Elio
AU - Kaaks, Rudolf
AU - Peeters, Petra H. M.
N1 - The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Research group of Nutrition Epidemiology (013242550), Pathology, (Lund) (013030000)
PY - 2012
Y1 - 2012
N2 - Background: In 2007 the World Cancer Research Fund Report concluded that there was limited and inconsistent evidence for an effect of coffee and tea consumption on the risk of epithelial ovarian cancer (EOC). Objective: In the European Prospective Investigation into Cancer and Nutrition (EPIC), we aimed to investigate whether coffee intakes, tea intakes, or both are associated with the risk of EOC. Design: All women participating in the EPIC (n = 330,849) were included in this study. Data on coffee and tea consumption were collected through validated food-frequency questionnaires at baseline. HRs and 95% CIs were estimated by using Cox proportional hazards models. Furthermore, we performed an updated meta-analysis of all previous prospective studies until April 2011 by comparing the highest and lowest coffee- and tea-consumption categories as well as by using dose-response random-effects meta-regression analyses. Results: During a median follow-up of 11.7 y, 1244 women developed EOC. No association was observed between the risk of EOC and coffee consumption [HR: 1.05 (95% CI: 0.75, 1.46) for the top quintile compared with no intake] or tea consumption [HR: 1.07 (95% Cl: 0.78, 1.45) for the top quintile compared with no intake]. This lack of association between coffee and tea intake and EOC risk was confirmed by the results of our meta-analysis. Conclusion: Epidemiologic studies do not provide sufficient evidence to support an association between coffee and tea consumption and risk of ovarian cancer. Am J Clin Nutr 2012;95:1172-81.
AB - Background: In 2007 the World Cancer Research Fund Report concluded that there was limited and inconsistent evidence for an effect of coffee and tea consumption on the risk of epithelial ovarian cancer (EOC). Objective: In the European Prospective Investigation into Cancer and Nutrition (EPIC), we aimed to investigate whether coffee intakes, tea intakes, or both are associated with the risk of EOC. Design: All women participating in the EPIC (n = 330,849) were included in this study. Data on coffee and tea consumption were collected through validated food-frequency questionnaires at baseline. HRs and 95% CIs were estimated by using Cox proportional hazards models. Furthermore, we performed an updated meta-analysis of all previous prospective studies until April 2011 by comparing the highest and lowest coffee- and tea-consumption categories as well as by using dose-response random-effects meta-regression analyses. Results: During a median follow-up of 11.7 y, 1244 women developed EOC. No association was observed between the risk of EOC and coffee consumption [HR: 1.05 (95% CI: 0.75, 1.46) for the top quintile compared with no intake] or tea consumption [HR: 1.07 (95% Cl: 0.78, 1.45) for the top quintile compared with no intake]. This lack of association between coffee and tea intake and EOC risk was confirmed by the results of our meta-analysis. Conclusion: Epidemiologic studies do not provide sufficient evidence to support an association between coffee and tea consumption and risk of ovarian cancer. Am J Clin Nutr 2012;95:1172-81.
U2 - 10.3945/ajcn.111.026393
DO - 10.3945/ajcn.111.026393
M3 - Article
C2 - 22440851
SN - 1938-3207
VL - 95
SP - 1172
EP - 1181
JO - American Journal of Clinical Nutrition
JF - American Journal of Clinical Nutrition
IS - 5
ER -
