TY - JOUR
T1 - Different postprandial metabolic patterns after the consumption of fish oil and lard in healthy Chinese individuals
AU - Zhu, Ao Shuang
AU - Zhao, Jian Zhong
AU - Wang, Shi Zhong
AU - Ma, Ling Di
AU - Xia, Lei
AU - Nilsson-Ehle, Peter
AU - Xu, Ning
PY - 2017
Y1 - 2017
N2 - Aim: It is well known that nutritional intervention has positive effects on the secondary prevention of coronary heart disease. Different fat compositions of meals may alter postprandial plasma lipid patterns, which can further influence lipid metabolism in vivo. Methods: In the present study, we investigated postprandial plasma lipid parameters in twenty healthy volunteers after eating fat meals either with 80 gram lard or 80 gram fish oil. Blood samples were drawn at 0, 0.5, 1, 2, 3, 5 and 7. hours and plasma levels of total triglycerides (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were determined. Results: It demonstrated that postprandial plasma concentrations of TG, TC and LDL-C were significantly lower whereas HDL-C was higher after eating fish oil compared to the consumption of lard. Moreover, comparing the individuals with or without dyslipidemic family history, the healthy individuals without family history of dyslipidemia after eating fish oil had even lower postprandial plasma TG and LDL-C (P <. 0.05) than the subjects with the family history. It is concluded that postprandial response following fish oil could be as a result of reduced TG, TC and LDL-C, and increased HDL-C. Conclusions: Postprandial responses following fish oil consumption may reduce TG, TC and LDL-C plasma levels, and increase HDL-C level. Individuals with dyslipidemic family history may have enhanced postprandial response than the individuals without dyslipidemic family history.
AB - Aim: It is well known that nutritional intervention has positive effects on the secondary prevention of coronary heart disease. Different fat compositions of meals may alter postprandial plasma lipid patterns, which can further influence lipid metabolism in vivo. Methods: In the present study, we investigated postprandial plasma lipid parameters in twenty healthy volunteers after eating fat meals either with 80 gram lard or 80 gram fish oil. Blood samples were drawn at 0, 0.5, 1, 2, 3, 5 and 7. hours and plasma levels of total triglycerides (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were determined. Results: It demonstrated that postprandial plasma concentrations of TG, TC and LDL-C were significantly lower whereas HDL-C was higher after eating fish oil compared to the consumption of lard. Moreover, comparing the individuals with or without dyslipidemic family history, the healthy individuals without family history of dyslipidemia after eating fish oil had even lower postprandial plasma TG and LDL-C (P <. 0.05) than the subjects with the family history. It is concluded that postprandial response following fish oil could be as a result of reduced TG, TC and LDL-C, and increased HDL-C. Conclusions: Postprandial responses following fish oil consumption may reduce TG, TC and LDL-C plasma levels, and increase HDL-C level. Individuals with dyslipidemic family history may have enhanced postprandial response than the individuals without dyslipidemic family history.
KW - Fish oil
KW - Healthy individuals
KW - Lard
KW - Lipid metabolism
KW - Postprandial
UR - http://www.scopus.com/inward/record.url?scp=85011076379&partnerID=8YFLogxK
U2 - 10.1016/j.nupar.2016.12.002
DO - 10.1016/j.nupar.2016.12.002
M3 - Article
AN - SCOPUS:85011076379
SN - 0985-0562
VL - 31
SP - 134
EP - 139
JO - Nutrition Clinique et Metabolisme
JF - Nutrition Clinique et Metabolisme
IS - 2
ER -