Dynamic susceptibility contrast MRI with a prebolus contrast agent administration design for improved absolute quantification of perfusion.

Linda Knutsson; Emelie Lind; André Ahlgren; Matthias J P van Osch; Karin Markenroth Bloch; Yulia Surova; Freddy Ståhlberg; Danielle van Westen; Ronnie Wirestam

doi:10.1002/mrm.25006

Dynamic susceptibility contrast MRI with a prebolus contrast agent administration design for improved absolute quantification of perfusion.

Linda Knutsson, Emelie Lind, André Ahlgren, Matthias J P van Osch, Karin Markenroth Bloch, Yulia Surova, Freddy Ståhlberg, Danielle van Westen, Ronnie Wirestam

Leiden University Medical Centre

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

Sammanfattning

Arterial partial-volume effects (PVEs) often hamper reproducible absolute quantification of cerebral blood flow (CBF) and cerebral blood volume (CBV) obtained by dynamic susceptibility contrast MRI (DSC-MRI). The aim of this study was to examine whether arterial PVEs in DSC-MRI data can be minimized by rescaling the arterial input function (AIF) using a sagittal-sinus venous output function obtained following a prebolus administration of a low dose of contrast agent.

Originalspråk	engelska
Sidor (från-till)	996-1006
Tidskrift	Magnetic Resonance in Medicine
Volym	72
Nummer	4
DOI	https://doi.org/10.1002/mrm.25006
Status	Published - 2014

Ämnesklassifikation (UKÄ)

Radiologi och bildbehandling
Annan fysik

Tillgång till dokument

10.1002/mrm.25006

http://www.ncbi.nlm.nih.gov/pubmed/24285621?dopt=Abstract

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Link to publication in Scopus

1 Doktorsavhandling (sammanläggning)

MRI Perfusion Measurements using Magnetic Susceptibility Effects: Calibration Approaches and Contrast Agent Quantification
Lind, E., 2019 feb., Lund: Naturvetenskapliga fakulteten, Lunds universitet. 181 s.
Forskningsoutput: Avhandling › Doktorsavhandling (sammanläggning)

Öppen tillgång
Fil

1 Aktiva

Optimisation and Validation of Dynamic Susceptibility Contrast MRI
Knutsson, L. (PI) & Wirestam, R. (PI)
1997/01/01 → …
Projekt: Forskning

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title = "Dynamic susceptibility contrast MRI with a prebolus contrast agent administration design for improved absolute quantification of perfusion.",

abstract = "Arterial partial-volume effects (PVEs) often hamper reproducible absolute quantification of cerebral blood flow (CBF) and cerebral blood volume (CBV) obtained by dynamic susceptibility contrast MRI (DSC-MRI). The aim of this study was to examine whether arterial PVEs in DSC-MRI data can be minimized by rescaling the arterial input function (AIF) using a sagittal-sinus venous output function obtained following a prebolus administration of a low dose of contrast agent.",

author = "Linda Knutsson and Emelie Lind and Andr{\'e} Ahlgren and \{van Osch\}, \{Matthias J P\} and \{Markenroth Bloch\}, Karin and Yulia Surova and Freddy St{\aa}hlberg and \{van Westen\}, Danielle and Ronnie Wirestam",

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doi = "10.1002/mrm.25006",

language = "English",

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TY - JOUR

T1 - Dynamic susceptibility contrast MRI with a prebolus contrast agent administration design for improved absolute quantification of perfusion.

AU - Knutsson, Linda

AU - Lind, Emelie

AU - Ahlgren, André

AU - van Osch, Matthias J P

AU - Markenroth Bloch, Karin

AU - Surova, Yulia

AU - Ståhlberg, Freddy

AU - van Westen, Danielle

AU - Wirestam, Ronnie

PY - 2014

Y1 - 2014

N2 - Arterial partial-volume effects (PVEs) often hamper reproducible absolute quantification of cerebral blood flow (CBF) and cerebral blood volume (CBV) obtained by dynamic susceptibility contrast MRI (DSC-MRI). The aim of this study was to examine whether arterial PVEs in DSC-MRI data can be minimized by rescaling the arterial input function (AIF) using a sagittal-sinus venous output function obtained following a prebolus administration of a low dose of contrast agent.

AB - Arterial partial-volume effects (PVEs) often hamper reproducible absolute quantification of cerebral blood flow (CBF) and cerebral blood volume (CBV) obtained by dynamic susceptibility contrast MRI (DSC-MRI). The aim of this study was to examine whether arterial PVEs in DSC-MRI data can be minimized by rescaling the arterial input function (AIF) using a sagittal-sinus venous output function obtained following a prebolus administration of a low dose of contrast agent.

UR - https://www.scopus.com/pages/publications/84927691578

U2 - 10.1002/mrm.25006

DO - 10.1002/mrm.25006

M3 - Article

C2 - 24285621

SN - 1522-2594

VL - 72

SP - 996

EP - 1006

JO - Magnetic Resonance in Medicine

JF - Magnetic Resonance in Medicine

IS - 4

ER -

Dynamic susceptibility contrast MRI with a prebolus contrast agent administration design for improved absolute quantification of perfusion.

Sammanfattning

Ämnesklassifikation (UKÄ)

Tillgång till dokument

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Fingeravtryck

Forskningsoutput

MRI Perfusion Measurements using Magnetic Susceptibility Effects: Calibration Approaches and Contrast Agent Quantification

Projekt

Optimisation and Validation of Dynamic Susceptibility Contrast MRI

Citera det här