Effect of nanoparticle size and magnetic field strength on the displacement signal in magnetomotive ultrasound imaging

Roger Andersson, Maria Evertsson, Hanna Toftevall, Magnus Cinthio, Sarah Fredriksson, Tomas Jansson

Forskningsoutput: Kapitel i bok/rapport/Conference proceedingKonferenspaper i proceedingPeer review

Sammanfattning

Magnetomotive ultrasound imaging is an emerging technique where superparamagnetic iron oxide nanoparticles can be used as an ultrasound contrast agent. A time-varying external magnetic field acts to move tissue embedded particles, and ultrasound is used to detect the resulting tissue movement. In this experimental phantom study we observed a variation in the magnetomotive response in respect to physical size of the embedded superparamagnetic iron oxide nanoparticles. Given the same Fe concentration a weaker response, by a factor of 2, was detected with the larger nanoparticles. However, approximately seven times larger response remains, given the volume ratio between particles, implying a seven times larger response per binding event. We hypothesize that this can have bearing in molecular imaging.

Originalspråkengelska
Titel på värdpublikation2016 IEEE International Ultrasonics Symposium, IUS 2016
FörlagIEEE Computer Society
Volym2016-November
ISBN (elektroniskt)9781467398978
DOI
StatusPublished - 2016 nov. 1
Evenemang2016 IEEE International Ultrasonics Symposium, IUS 2016 - Tours, Frankrike
Varaktighet: 2016 sep. 182016 sep. 21

Konferens

Konferens2016 IEEE International Ultrasonics Symposium, IUS 2016
Land/TerritoriumFrankrike
OrtTours
Period2016/09/182016/09/21

Ämnesklassifikation (UKÄ)

  • Radiologi och bildbehandling

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