Effects of dietary fibers on the tuft cell population in the mouse colon post radiation

Ulrikke Voss; Dilip Kumar Malipatlolla; Piyush Patel; Sravani Devarakonda; F. Sjöberg; R. Grandér; Ana Rascon; Margareta Nyman; G. Steineck; C. Bull

doi:10.1111/nmo.13671

Effects of dietary fibers on the tuft cell population in the mouse colon post radiation

Ulrikke Voss, Dilip Kumar Malipatlolla, Piyush Patel, Sravani Devarakonda, F. Sjöberg, R. Grandér, Ana Rascon, Margareta Nyman, G. Steineck, C. Bull

Göteborgs universitet

Forskningsoutput: Tidskriftsbidrag › Publicerat konferensabstract

Sammanfattning

Pelvic radiation therapy is often associated with gastrointestinal dysfunction. Intestinal tuft cell located within the mucosal epithelium have in the small intestine following full body radiation in mice been shown to be essential for epithelial regeneration. Dietary approaches during and after radiation therapy have also been suggested to aid epithelial health and function. Tuft cells are suggested to be important for translation of chemosensory signals in the lumen. This study investigated the effects of dietary fiber composition on tuft cell numbers in the colon at 1, 6 and 18 weeks post radiation.

Originalspråk	engelska
Sidor (från-till)	150
Tidskrift	Neurogastroenterology and Motility
Volym	31
Nummer	S4
DOI	https://doi.org/10.1111/nmo.13671
Status	Published - 2019
Evenemang	NeuroGastro 2019: Biennial Meeting of the European Society of Neurogastroenterology and Motility - Lisbon, Portugal Varaktighet: 2019 sep. 5 → 2019 sep. 7 http://www.neurogastro2019.org/

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10.1111/nmo.13671

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@article{ff6e7a7eee7c4246abd1670ae5cc288c,

title = "Effects of dietary fibers on the tuft cell population in the mouse colon post radiation",

abstract = "Pelvic radiation therapy is often associated with gastrointestinal dysfunction. Intestinal tuft cell located within the mucosal epithelium have in the small intestine following full body radiation in mice been shown to be essential for epithelial regeneration. Dietary approaches during and after radiation therapy have also been suggested to aid epithelial health and function. Tuft cells are suggested to be important for translation of chemosensory signals in the lumen. This study investigated the effects of dietary fiber composition on tuft cell numbers in the colon at 1, 6 and 18 weeks post radiation.",

author = "Ulrikke Voss and Malipatlolla, {Dilip Kumar} and Piyush Patel and Sravani Devarakonda and F. Sj{\"o}berg and R. Grand{\'e}r and Ana Rascon and Margareta Nyman and G. Steineck and C. Bull",

year = "2019",

doi = "10.1111/nmo.13671",

language = "English",

volume = "31",

pages = "150",

journal = "Neurogastroenterology and Motility",

issn = "1365-2982",

publisher = "Wiley-Blackwell",

number = "S4",

note = "NeuroGastro 2019 : Biennial Meeting of the European Society of Neurogastroenterology and Motility ; Conference date: 05-09-2019 Through 07-09-2019",

url = "http://www.neurogastro2019.org/",

}

TY - JOUR

T1 - Effects of dietary fibers on the tuft cell population in the mouse colon post radiation

AU - Voss, Ulrikke

AU - Malipatlolla, Dilip Kumar

AU - Patel, Piyush

AU - Devarakonda, Sravani

AU - Sjöberg, F.

AU - Grandér, R.

AU - Rascon, Ana

AU - Nyman, Margareta

AU - Steineck, G.

AU - Bull, C.

PY - 2019

Y1 - 2019

N2 - Pelvic radiation therapy is often associated with gastrointestinal dysfunction. Intestinal tuft cell located within the mucosal epithelium have in the small intestine following full body radiation in mice been shown to be essential for epithelial regeneration. Dietary approaches during and after radiation therapy have also been suggested to aid epithelial health and function. Tuft cells are suggested to be important for translation of chemosensory signals in the lumen. This study investigated the effects of dietary fiber composition on tuft cell numbers in the colon at 1, 6 and 18 weeks post radiation.

AB - Pelvic radiation therapy is often associated with gastrointestinal dysfunction. Intestinal tuft cell located within the mucosal epithelium have in the small intestine following full body radiation in mice been shown to be essential for epithelial regeneration. Dietary approaches during and after radiation therapy have also been suggested to aid epithelial health and function. Tuft cells are suggested to be important for translation of chemosensory signals in the lumen. This study investigated the effects of dietary fiber composition on tuft cell numbers in the colon at 1, 6 and 18 weeks post radiation.

U2 - 10.1111/nmo.13671

DO - 10.1111/nmo.13671

M3 - Published meeting abstract

SN - 1365-2982

VL - 31

SP - 150

JO - Neurogastroenterology and Motility

JF - Neurogastroenterology and Motility

IS - S4

T2 - NeuroGastro 2019

Y2 - 5 September 2019 through 7 September 2019

ER -

Effects of dietary fibers on the tuft cell population in the mouse colon post radiation

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