Effects of oxygen therapy on wall-motion score index in patients with ST elevation myocardial infarction-the randomized SOCCER trial

Ardavan Khoshnood, Mahin Akbarzadeh Mameghanilar, Anders Roijer, Carl Meurling, Marcus Carlsson, Pallonji Bhiladvala, Peter Höglund, David Sparv, Lizbet Todorova, Arash Mokhtari, David Erlinge, Ulf Ekelund

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

8 Citeringar (SciVal)

Sammanfattning

Background: Although oxygen (O2) is routinely used in patients with acute myocardial infarction (AMI), it may have negative effects. In this substudy of the SOCCER trial, we aimed to evaluate the effects of O2-treatment on myocardial function in patients with ST elevation myocardial infarction (STEMI). Methods: Normoxic (≥94%) STEMI patients were randomized in the ambulance to either supplemental O2 or room air until the end of the percutaneous coronary intervention (PCI). The patients underwent echocardiography on day 2-3 after the PCI and once again after 6 months. The study endpoints were wall-motion score index (WMSI) and left ventricular ejection fraction (LVEF). Results: Forty-six patients in the O2 group and 41 in the air group were included in the analysis. The index echocardiography showed no significant differences between the groups in WMSI (1.32±0.27 for O2 group vs 1.28±0.28 for air group) or LVEF (47.0±8.5% vs 49.2±8.1%). Nor were there differences at 6 months in WMSI (1.16±0.25 vs 1.14±0.24) or LVEF (53.5±5.8% vs 53.5±6.9%). Conclusion: The present findings indicate no harm or benefit of supplemental O2 on myocardial function in STEMI patients. Our results support that it is safe to withhold supplemental O2 in normoxic STEMI patients.

Originalspråkengelska
Sidor (från-till)1130-1137
Antal sidor8
TidskriftEchocardiography
Volym34
Utgåva8
DOI
StatusPublished - 2017

Ämnesklassifikation (UKÄ)

  • Kardiologi
  • Fysiologi
  • Annan klinisk medicin

Nyckelord

  • Kardiologi
  • Akutsjukvård
  • Syrgasbehandling
  • STEMI
  • Ultraljud

Fingeravtryck

Utforska forskningsämnen för ”Effects of oxygen therapy on wall-motion score index in patients with ST elevation myocardial infarction-the randomized SOCCER trial”. Tillsammans bildar de ett unikt fingeravtryck.

Citera det här