TY - JOUR
T1 - Exercise, bone mass and bone size in prepubertal boys: one-year data from the pediatric osteoporosis prevention study.
AU - Lindén, Christian
AU - Alwis, Gayani
AU - Ahlborg, Henrik
AU - Gardsell, P
AU - Valdimarsson, Örnolfur
AU - Stenevi Lundgren, Susanna
AU - Besjakov, Jack
AU - Karlsson, M K
N1 - The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Reconstructive Surgery (013240300), Clinical and Molecular Osteoporosis Research Unit (013242930), Medical Radiology Unit (013241410)
PY - 2007
Y1 - 2007
N2 - This non-randomized prospective controlled study evaluates a daily school-based exercise intervention program of 40 min/school day for I year in a population-based cohort of 81 boys aged 7-9 years. Controls were 57 age-matched boys assigned to the general school curriculum of 60min/ week. Bone mineral content BMC; g) and areal bone mineral density (aBMD; g/cm(2)) were measured with dual X-ray absorptiometry (DXA) of the total body, the third lumbar vertebra (L3) and the femoral neck (FN). Bone width for L3 and FN was calculated from the lumbar spine and hip scan. No differences between the groups were found at baseline in age, anthropometrics or bone parameters. The mean annual gain in L3 BMC was 5.9 percentage points higher (P < 0.001), L3 aBMD a mean 2.1 percentage points higher (P = 0.01) and L3 width a mean 2.3 percentage points higher (P = 0.001) in the cases than in the controls. When all individuals were included in one cohort, the total duration of exercise including both school-based and spare-time training correlated with L3 BMC (r = 0.26, P = 0.003), L3 aBMD (r = 0.18, P = 0.04) and L3 width (r = 0.24, P = 0.006). The study suggests that exercise in pre-pubertal boys influences the accrual of bone mineral and bone width and that a 1-year school-based exercise program confers skeletal benefits, at least in the lumbar spine.
AB - This non-randomized prospective controlled study evaluates a daily school-based exercise intervention program of 40 min/school day for I year in a population-based cohort of 81 boys aged 7-9 years. Controls were 57 age-matched boys assigned to the general school curriculum of 60min/ week. Bone mineral content BMC; g) and areal bone mineral density (aBMD; g/cm(2)) were measured with dual X-ray absorptiometry (DXA) of the total body, the third lumbar vertebra (L3) and the femoral neck (FN). Bone width for L3 and FN was calculated from the lumbar spine and hip scan. No differences between the groups were found at baseline in age, anthropometrics or bone parameters. The mean annual gain in L3 BMC was 5.9 percentage points higher (P < 0.001), L3 aBMD a mean 2.1 percentage points higher (P = 0.01) and L3 width a mean 2.3 percentage points higher (P = 0.001) in the cases than in the controls. When all individuals were included in one cohort, the total duration of exercise including both school-based and spare-time training correlated with L3 BMC (r = 0.26, P = 0.003), L3 aBMD (r = 0.18, P = 0.04) and L3 width (r = 0.24, P = 0.006). The study suggests that exercise in pre-pubertal boys influences the accrual of bone mineral and bone width and that a 1-year school-based exercise program confers skeletal benefits, at least in the lumbar spine.
KW - bone mineral density
KW - bone width
KW - boys
KW - tanner I
KW - prepubertal
KW - physical activity
KW - bone mineral content
U2 - 10.1111/j.1600-0838.2006.00568.x
DO - 10.1111/j.1600-0838.2006.00568.x
M3 - Article
SN - 1600-0838
VL - 17
SP - 340
EP - 347
JO - Scandinavian Journal of Medicine & Science in Sports
JF - Scandinavian Journal of Medicine & Science in Sports
IS - 4
ER -