Fallbeskrivning. Rosiglitazonbehandling gav kraftfull effekt, men fick ändå avbrytas

Martin Ridderstråle, Leif Groop

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

Sammanfattning

The thiazolidinediones were introduced as oral hypoglycemic drugs in Sweden during the fall of 2000. A case is reported in which a woman with insulin-dependent type-2 diabetes and both macro- and microangiopathy and pronounced insulin resistance was treated with rosiglitazone (Avandia). Within three months insulin doses could be reduced by 36% (from 176 to 112 units insulin daily) and concomitantly Ery-HbA1c was reduced from 8.4 to 5.3%. In spite of this dramatic effect on glucose homeostasis administration of the drug had to be discontinued due to critical congestive heart failure.
Bidragets översatta titel A case report. Rosiglitazone treatment was highly effective yet had to be terminated
Originalspråksvenska
Sidor (från-till)407-410
TidskriftLäkartidningen
Volym99
Nummer5
StatusPublished - 2002

Ämnesklassifikation (UKÄ)

  • Endokrinologi och diabetes
  • Näringslära och dietkunskap

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