Genome assembly, sex-biased gene expression and dosage compensation in the damselfly Ischnura elegans

Pallavi Chauhan, Janne Swaegers, Rosa A. Sánchez-Guillén, Erik I. Svensson, Maren Wellenreuther, Bengt Hansson

Forskningsoutput: TidskriftsbidragArtikel i vetenskaplig tidskriftPeer review

Sammanfattning

The evolution of sex chromosomes, and patterns of sex-biased gene expression and dosage compensation, are poorly known among early winged insects such as odonates. We assembled and annotated the genome of Ischnura elegans (blue-tailed damselfly), which, like other odonates, has a male-hemigametic sex-determining system (X0 males, XX females). By identifying X-linked genes in I. elegans and their orthologs in other insect genomes, we found homologies between the X chromosome in odonates and chromosomes of other orders, including the X chromosome in Coleoptera. Next, we showed balanced expression of X-linked genes between sexes in adult I. elegans, i.e. evidence of dosage compensation. Finally, among the genes in the sex-determining pathway only fruitless was found to be X-linked, while only doublesex showed sex-biased expression. This study reveals partly conserved sex chromosome synteny and independent evolution of dosage compensation among insect orders separated by several hundred million years of evolutionary history.

Originalspråkengelska
Sidor (från-till)1828-1837
Antal sidor10
TidskriftGenomics
Volym113
Nummer4
DOI
StatusPublished - 2021 juli 1

Ämnesklassifikation (UKÄ)

  • Genetik

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