Glucose transport machinery reconstituted in cell models.

Jesper Söndergaard Hansen; Karin Elbing; James R Thompson; Noah Malmstadt; Karin Lindkvist

doi:10.1039/c4cc08838g

Glucose transport machinery reconstituted in cell models.

Jesper Söndergaard Hansen, Karin Elbing, James R Thompson, Noah Malmstadt, Karin Lindkvist

Medicinsk strukturbiologi

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

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Here we demonstrate the production of a functioning cell model by formation of giant vesicles reconstituted with the GLUT1 glucose transporter and a glucose oxidase and hydrogen peroxidase linked fluorescent reporter internally. Hence, a simplified artificial cell is formed that is able to take up glucose and process it.

Originalspråk	engelska
Sidor (från-till)	2316-2319
Tidskrift	Chemical Communications
Volym	51
Nummer	12
DOI	https://doi.org/10.1039/c4cc08838g
Status	Published - 2015

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10.1039/c4cc08838g

http://www.ncbi.nlm.nih.gov/pubmed/25562394?dopt=Abstract

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title = "Glucose transport machinery reconstituted in cell models.",

abstract = "Here we demonstrate the production of a functioning cell model by formation of giant vesicles reconstituted with the GLUT1 glucose transporter and a glucose oxidase and hydrogen peroxidase linked fluorescent reporter internally. Hence, a simplified artificial cell is formed that is able to take up glucose and process it.",

author = "{S{\"o}ndergaard Hansen}, Jesper and Karin Elbing and Thompson, {James R} and Noah Malmstadt and Karin Lindkvist",

year = "2015",

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T1 - Glucose transport machinery reconstituted in cell models.

AU - Söndergaard Hansen, Jesper

AU - Elbing, Karin

AU - Thompson, James R

AU - Malmstadt, Noah

AU - Lindkvist, Karin

PY - 2015

Y1 - 2015

N2 - Here we demonstrate the production of a functioning cell model by formation of giant vesicles reconstituted with the GLUT1 glucose transporter and a glucose oxidase and hydrogen peroxidase linked fluorescent reporter internally. Hence, a simplified artificial cell is formed that is able to take up glucose and process it.

AB - Here we demonstrate the production of a functioning cell model by formation of giant vesicles reconstituted with the GLUT1 glucose transporter and a glucose oxidase and hydrogen peroxidase linked fluorescent reporter internally. Hence, a simplified artificial cell is formed that is able to take up glucose and process it.

U2 - 10.1039/c4cc08838g

DO - 10.1039/c4cc08838g

M3 - Article

C2 - 25562394

SN - 1364-548X

VL - 51

SP - 2316

EP - 2319

JO - Chemical Communications

JF - Chemical Communications

IS - 12

ER -

Glucose transport machinery reconstituted in cell models.

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