HLA‐DR3, DQ2 homozygosity in two patients with insulin‐dependent diabetes mellitus superimposed with ulcerative colitis and primary sclerosing cholangitis

S ‐A Ivarsson; S. ERIKSSON; I. KOCKUM; Å LERNMARK; S. LINDGREN; K. O. NILSSON; G. SUNDKVIST; R. WASSMUTH

doi:10.1111/j.1365-2796.1993.tb00988.x

HLA‐DR3, DQ2 homozygosity in two patients with insulin‐dependent diabetes mellitus superimposed with ulcerative colitis and primary sclerosing cholangitis

S ‐A Ivarsson, S. ERIKSSON, I. KOCKUM, Å LERNMARK, S. LINDGREN, K. O. NILSSON, G. SUNDKVIST, R. WASSMUTH

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

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Abstract. Two unrelated young males with the unusual simultaneous presence of insulin‐dependent diabetes mellitus, ulcerative colitis and primary sclerosing cholangitis are reported. Both patients manifested homozygosity for the DR3‐DQw2 (DQB*0201) HLA genotypes. We believe that homozygosity for this genotype may predispose for this type of multi‐organ autoimmune disease. 1993 Blackwell Publishing Ltd

Originalspråk	engelska
Sidor (från-till)	281-286
Tidskrift	Journal of Internal Medicine
Volym	233
Nummer	3
DOI	https://doi.org/10.1111/j.1365-2796.1993.tb00988.x
Status	Published - 1993 jan. 1

Ämnesklassifikation (UKÄ)

Endokrinologi och diabetes

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Ivarsson, S. A., ERIKSSON, S., KOCKUM, I., LERNMARK, Å., LINDGREN, S., NILSSON, K. O., SUNDKVIST, G., & WASSMUTH, R. (1993). HLA‐DR3, DQ2 homozygosity in two patients with insulin‐dependent diabetes mellitus superimposed with ulcerative colitis and primary sclerosing cholangitis. Journal of Internal Medicine, 233(3), 281-286. https://doi.org/10.1111/j.1365-2796.1993.tb00988.x

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title = "HLA‐DR3, DQ2 homozygosity in two patients with insulin‐dependent diabetes mellitus superimposed with ulcerative colitis and primary sclerosing cholangitis",

abstract = "Abstract. Two unrelated young males with the unusual simultaneous presence of insulin‐dependent diabetes mellitus, ulcerative colitis and primary sclerosing cholangitis are reported. Both patients manifested homozygosity for the DR3‐DQw2 (DQB*0201) HLA genotypes. We believe that homozygosity for this genotype may predispose for this type of multi‐organ autoimmune disease. 1993 Blackwell Publishing Ltd",

keywords = "diabetes mellitus type I, sclerosing cholangitis, ulcerative colitis",

author = "Ivarsson, {S ‐A} and S. ERIKSSON and I. KOCKUM and {\AA} LERNMARK and S. LINDGREN and NILSSON, {K. O.} and G. SUNDKVIST and R. WASSMUTH",

year = "1993",

month = jan,

day = "1",

doi = "10.1111/j.1365-2796.1993.tb00988.x",

language = "English",

volume = "233",

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journal = "Journal of Internal Medicine",

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Ivarsson, SA, ERIKSSON, S, KOCKUM, I, LERNMARK, Å, LINDGREN, S, NILSSON, KO, SUNDKVIST, G & WASSMUTH, R 1993, 'HLA‐DR3, DQ2 homozygosity in two patients with insulin‐dependent diabetes mellitus superimposed with ulcerative colitis and primary sclerosing cholangitis', Journal of Internal Medicine, vol. 233, nr. 3, s. 281-286. https://doi.org/10.1111/j.1365-2796.1993.tb00988.x

HLA‐DR3, DQ2 homozygosity in two patients with insulin‐dependent diabetes mellitus superimposed with ulcerative colitis and primary sclerosing cholangitis. / Ivarsson, S ‐A; ERIKSSON, S.; KOCKUM, I. et al.
I: Journal of Internal Medicine, Vol. 233, Nr. 3, 01.01.1993, s. 281-286.

Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift › Peer review

TY - JOUR

T1 - HLA‐DR3, DQ2 homozygosity in two patients with insulin‐dependent diabetes mellitus superimposed with ulcerative colitis and primary sclerosing cholangitis

AU - Ivarsson, S ‐A

AU - ERIKSSON, S.

AU - KOCKUM, I.

AU - LERNMARK, Å

AU - LINDGREN, S.

AU - NILSSON, K. O.

AU - SUNDKVIST, G.

AU - WASSMUTH, R.

PY - 1993/1/1

Y1 - 1993/1/1

N2 - Abstract. Two unrelated young males with the unusual simultaneous presence of insulin‐dependent diabetes mellitus, ulcerative colitis and primary sclerosing cholangitis are reported. Both patients manifested homozygosity for the DR3‐DQw2 (DQB*0201) HLA genotypes. We believe that homozygosity for this genotype may predispose for this type of multi‐organ autoimmune disease. 1993 Blackwell Publishing Ltd

AB - Abstract. Two unrelated young males with the unusual simultaneous presence of insulin‐dependent diabetes mellitus, ulcerative colitis and primary sclerosing cholangitis are reported. Both patients manifested homozygosity for the DR3‐DQw2 (DQB*0201) HLA genotypes. We believe that homozygosity for this genotype may predispose for this type of multi‐organ autoimmune disease. 1993 Blackwell Publishing Ltd

KW - diabetes mellitus type I

KW - sclerosing cholangitis

KW - ulcerative colitis

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U2 - 10.1111/j.1365-2796.1993.tb00988.x

DO - 10.1111/j.1365-2796.1993.tb00988.x

M3 - Article

C2 - 8450297

AN - SCOPUS:0027415112

SN - 0954-6820

VL - 233

SP - 281

EP - 286

JO - Journal of Internal Medicine

JF - Journal of Internal Medicine

IS - 3

ER -

HLA‐DR3, DQ2 homozygosity in two patients with insulin‐dependent diabetes mellitus superimposed with ulcerative colitis and primary sclerosing cholangitis

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