High levels of the antimicrobial peptide, LL-37, are detected in gingival crevicular fluid from patients with chronic periodontitis. LL-37 not only shows antimicrobial activity but also affects host-cell viability. The objective of the present study was to identify endogenous mechanisms that antagonize the detrimental effects of LL-37 on osteoblast viability, focusing on the human peptide p33 expressed on the surface of various cell types.
The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Vascular Physiology (013212034), Mucosal biology (013212033), Division of Infection Medicine (BMC) (013024020)